Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
This locus encodes an AT-rich DNA interacting domain-containing protein. Zusätzlich bieten wir Ihnen ARID1B Antikörper (43) und und viele weitere Produktgruppen zu diesem Protein an.
Showing 1 out of 1 products:
In the brain, Arid1b haploinsufficiency resulted in changes in the expression of SWI/SNF (zeige SNRPA ELISA Kits)-regulated genes implicated in neuropsychiatric disorders.
STAT3 (zeige STAT3 ELISA Kits)/Arid1b/beta-catenin (zeige CTNNB1 ELISA Kits) pathway is driving neurofibroma initiation.
The patterns of expression of ARID1A (zeige ARID1A ELISA Kits) and ARID1B genes through various mouse embryonic stages, was examined.
These data suggest that the BAF250B-associated SWI/SNF (zeige SNRPA ELISA Kits) is essential for mouse embryonic stem cells to maintain their normal proliferation and pluripotency.
A subset of mammalian SWI/SNF (zeige SNRPA ELISA Kits) complexes, specifically containing ARID1B, is required for efficient cell cycle re-entry and for association of activation factors with the c-myc (zeige MYC ELISA Kits) promoter.
we identified a subgroup of neuroblastoma with ARID1B mutation shows an aggressive behavior. These findings may provide a new biomarker to identify another subgroup of neuroblastoma with high-risk features.
these results highlighted the significant genetic contribution of the ARID1B variant, rs73013281, to susceptibility for HCC, especially in interaction with physical activity.
we identified concurrent ARID1A (zeige ARID1A ELISA Kits) and ARID1B inactivating mutations with consequent loss of protein expression in the undifferentiated component of approximately one-quarter of dedifferentiated endometrial and ovarian carcinomas
Of the 34 undifferentiated endometrial carcinomas examined, 17 (50%) exhibited SWI/SNF (zeige SNRPA ELISA Kits) complex inactivation, with 11 tumors showing complete loss of both ARID1A (zeige ARID1A ELISA Kits) and ARID1B, 5 showing complete loss of BRG1 (zeige SMARCA4 ELISA Kits) and 1 showing complete loss of INI1 (zeige SMARCB1 ELISA Kits). Ten of the remaining 17 undifferentiated carcinomas showed the following alterations: 5 tumors (15%) showed loss of ARID1A (zeige ARID1A ELISA Kits) only with intact ARID1B, BRG1 (zeige SMARCA4 ELISA Kits), and INI1 (zeige SMARCB1 ELISA Kits) expression.
We report here the clinical, genetic, and proteomic phenotypes of an individual with a unique apparent de novo mutation of ARID1B due to an intragenic duplication
HSCR was observed in a patient with a truncating mutation in ARID1B, further expanding the phenotypic spectrum of Coffin-Siris syndrome. This suggests that the BAF complex does not only play a role in the enteric system of Drosophila, but also in humans.
Case Report: Melanotic Xp11 renal cell carcinoma with ARID1B-TFE3 (zeige TFE3 ELISA Kits) gene fusion.
The clinical features of both patients are felt to be consistent with an ARID1B-related disorder. To our knowledge, this is the first report of a pathogenic mutation in ARID1B being passed from an affected parent to their offspring.
We report two teenagers with ID whose molecular diagnosis of a SMARC2A or ARID1B mutation, respectively, was established through clinical exome analysis.
The ARID1B gene, commonly mutated in multiple types of cancer, was identified as an additional ZNF384 gene fusion partner.
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described.
AT rich interactive domain 1B (Swi1 like)
, AT-rich interactive domain-containing protein 1B
, transcription factor 1
, ARID domain-containing protein 1B
, BRG1-associated factor 250b
, BRG1-binding protein ELD/OSA1
, ELD (eyelid)/OSA protein