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ARFRP1 encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. Zusätzlich bieten wir Ihnen ARFRP1 Antikörper (38) und ARFRP1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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NR2F2 loss-of-function mutation is associated with increased susceptibility to double outlet right ventricle and ventricular septal defect .
The results of the present study suggest that COUPTFII functions as a significant regulatory suppressor of gastric cancer growth and metastasis, and suggests that COUPTFII may serve as a novel diagnostic and prognostic biomarker for gastric cancer metastasis.
COUP-TFII is a critical factor controlling metastatic gene networks to promote prostate cancer metastasis.
fifth of COUP-TFI cells also co-expressed COUP-TFII, and cells expressing either transcription factor followed posterior or anterio-lateral pathways into the cortex
Results provide evidence that ARFRP1 is required for HCV propagation through its interaction with NS5A protein. Also, ARFRP1 is involved in the regulation of lipid droplet (LD) growth in HCV-infected cells and, recruits SNAP23 to sites in close proximity to LDs.
Dividing COUP-TFII+ progenitor cells were localized to ventral CGE
We showed that the orphan receptor COUP-TFII is an important player in hepatic neoangiogenesis. COUP-TFII expression in hepatic stellate cells (HSC) controls the crosstalk between hepatic HSC and endothelial cells coordinating vascular remodelling during liver injury.
Low COUPTFII expression is associated with prostate cancer.
ARFRP1 shifted from a predominantly cis-Golgi and endosome-to-trans-Golgi network localization to localizing both Golgi and non-Golgi vesicular structures in hNaa30-depleted cells.
We conclude that COUP-TFII mutations can cause diaphragmatic hernias, and should be included in the differential diagnosis of CDH (zeige CHDH ELISA Kits) patients, particularly those with comorbid congenital heart defects.
ARFRP1 and the Golgi apparatus play an important role in lipoprotein maturation in the liver.
The GTPase (zeige RACGAP1 ELISA Kits) ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium.
data indicate that ARFRP1 in the liver is involved in the regulation of IGF1 (zeige IGF1 ELISA Kits) secretion and GLUT2 (zeige SLC2A2 ELISA Kits) sorting and is thereby essential for normal growth and glycogen (zeige GYS1 ELISA Kits) storage
Arfrp1 appears to be involved in sorting of GLUT4 (zeige SLC2A4 ELISA Kits).
Lipid droplets of adipocytes of Arfrp1(-/-) mice were smaller and exhibited ultrastructural alterations, such as a disturbed interaction of small lipid particles with larger droplets.
ADP-ribosylation factor-like GTPase (zeige RACGAP1 ELISA Kits) ARFRP1 is required for trans-Golgi to plasma membrane trafficking of E-cadherin (zeige CDH1 ELISA Kits).
This study provides the first detailed analysis of the regional distribution of ARFRP1 in the mouse brain and a quantitative view of its changes following sleep deprivation.
These data suggest that lethality of Arfrp1 knockout embryos is due to a specific disruption of protein targeting, e.g., of ARL1 and Golgin-245, to the Golgi.
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified.
ADP-ribosylation factor-related protein 1
, ARF-related protein 1
, SCG10 like-protein
, helicase-like protein NHL
, ADP-ribosylation factor related protein 1
, putative ADP-ribosylation factor related protein 1 variant 1