ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 Proteine (ADAMTS8)

ADAMTS8 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Zusätzlich bieten wir Ihnen ADAMTS8 Antikörper (64) und ADAMTS8 Kits (24) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ADAMTS8 30806 P57110
ADAMTS8 11095 Q9UP79
Ratte ADAMTS8 ADAMTS8 300475  
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
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ADAMTS8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
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Weitere Proteine zu ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 (ADAMTS8) Interaktionspartnern

Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 (ADAMTS8) Interaktionspartner

  1. This study demonstrated that Cortical fast-spiking parvalbumin (zeige PVALB Proteine) interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8 in mice.

  2. ADAMTS-4 (zeige ADAMTS4 Proteine) expression was upregulated during the development of atherosclerosis in LDLR(-/-)ApoB(100/100) mice.

Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 (ADAMTS8) Interaktionspartner

  1. This study showed that ADAMTS1 (zeige ADAMTS1 Proteine), 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer)

  2. ADAMTS8 hypermethylation is associated with decreased expression in gastric cancer.

  3. Study uncovers the tumor suppressive function of ADAMTS8 and its frequent methylation in certain tumors could be developed as a potential biomarker.

  4. ADAMTS 8, CCL23 (zeige CCL23 Proteine), and TNFSF15 (zeige TNFSF15 Proteine) are implicated in anti-angiogenic activities

  5. Ability of ADAMTS-8 to cleave aggrecan (zeige ACAN Proteine) at aggrecanase (zeige ADAMTS4 Proteine)-susceptible Glu373-Ala374 peptide bond. Presence of ADAMTS-8 mRNA transcripts in normal and osteoarthritic human cartilage. (ADAMTS-8)

  6. Downdownregulation of METH-2 expression in primary NSCLC, often associated with promoter hypermethylation, is a frequent event, which may be related to the development of the disease.

  7. ADAMTS8 and ADAMTS15 (zeige ADAMTS15 Proteine) have emerged as novel predictors of survival in patients with breast carcinoma

  8. Immunohistochemistry and Western analysis indicated downregulation of ADAMTS-8 protein in >77% brain tumours. A role for ADAMTS-8 in brain tumorigenesis, warranting further investigation into its role in regulation of tumour angiogenesis.

  9. ADAMTS-4 (zeige ADAMTS4 Proteine) and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of atherosclerotic plaques

ADAMTS8 Protein Überblick

Protein Überblick

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

Genbezeichner und Symbole assoziert mit ADAMTS8

  • ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8)
  • ADAM metallopeptidase with thrombospondin type 1 motif 8 (adamts8)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 (Adamts8)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 8 (Adamts8)
  • ADAM-TS8 Protein
  • ADAMTS8 Protein
  • METH-2 Protein
  • METH2 Protein

Bezeichner auf Proteinebene für ADAMTS8

ADAM metallopeptidase with thrombospondin type 1 motif, 8 , A disintegrin and metalloproteinase with thrombospondin motifs 8 , ADAM-TS 8 , ADAM-TS8 , ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 , ADAMTS-8 , METH-2 , METH-8 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8

GENE ID SPEZIES
466852 Pan troglodytes
718962 Macaca mulatta
100076383 Ornithorhynchus anatinus
100387160 Callithrix jacchus
100456851 Pongo abelii
100469807 Ailuropoda melanoleuca
100497759 Xenopus (Silurana) tropicalis
100557571 Anolis carolinensis
30806 Mus musculus
11095 Homo sapiens
512544 Bos taurus
769222 Gallus gallus
100684302 Canis lupus familiaris
300475 Rattus norvegicus
101120031 Ovis aries
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