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ADAM33 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Zusätzlich bieten wir Ihnen ADAM33 Kits (27) und ADAM33 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal ADAM33 Primary Antibody für ELISA, WB - ABIN250494
Powell, Wicks, Holloway, Holgate, Davies: The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. in American journal of respiratory cell and molecular biology 2004
Show all 2 Pubmed References
Identification and preliminary characterization of mouse Adam33.
ADAM33 is not essential for growth or reproduction in the mouse and does not modulate baseline or allergen-induced airway responsiveness.
Adam33/Adam33 shows 2 significant increments in expression during lung morphogenesis, suggesting important developmental regulation.
Increased ADAM13 cleavage of cadherin 11produces the EC1-3 fragment which increases cranial neural crest cell invasiveness in vitro and blocks the repulsive contact inhibition of locomotion response in colliding cells.
Novel roles for Plk (zeige PLK1 Antikörper) and GSK3 regulation of ADAM13 function in cranial neural crest cell migration.
Data show that ADAM13 function is autonomous to cranial neural crest (CNC) tissue.
The cytoplasmic domain of ADAM13 regulates the expression of multiple genes in cranial neural crest, including the protease Calpain8-a.
Collectively, our findings suggest that 1,25(OH)2D3 inhibits VEGF (zeige VEGFA Antikörper)-induced ASM (zeige SMPD1 Antikörper) cell proliferation by suppressing VEGFR2 (zeige KDR Antikörper) and ERK1/2 activation and downregulating ADAM33. Further studies of these mechanisms are needed to facilitate the development of treatments for smooth muscle hyperplasia-associated diseases of the airway such as asthma.
meta-analysis suggested that ADAM33 polymorphisms rs2280091, rs2280090, rs2787094, rs44707 and rs528557 were significantly associated with a high risk of childhood asthma
There was a significant difference in the frequency of ADAM33 V4 polymorphism in both, asthmatic and COPD (zeige ARCN1 Antikörper) patients groups. No significant differences were found for T1 polymorphism. However, there were significant differences when haplotypes and diplotypes of ADAM33 V4/T1 were compared in all three groups. It can be concluded that the polymorphism V4 of ADAM33 is associated with asthma or COPD (zeige ARCN1 Antikörper) in Venezuelan patients.
Evidence from this meta-analysis demonstrates that ADAM33 T1 polymorphism might be associated with increased susceptibility to asthma among Asian children and that ADAM33 F + 1, T2, S2, or V4 polymorphism may be unrelated to susceptibility of childhood asthma.
enhances ADAM-33 expression and airway smooth muscle cell proliferation
An association between ADAM33 gene polymorphism and impaired lung functions was detected in wood dust-exposed workers.
This meta-analysis demonstrates that the ADAM33 gene polymorphisms confer susceptibility to allergic rhinitis
findings suggest that genetic variants of ADAM33 gene may play important roles in asthma susceptibility in the Punjabi population of Pakistan
We investigated the influence of ADAM33 polymorphisms on the serum levels of ADAM33 and the susceptibility to pediatric asthma in the Chinese Han population
ADAM33 and ADAM12 (zeige ADAM12 Antikörper) genetic polymorphisms and their expression in Egyptian children with asthma
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
a disintegrin and metalloprotease 13
, disintegrin and metalloproteinase domain-containing protein 33
, ADAM metallopeptidase domain 33
, disintegrin and metalloproteinase domain-containing protein 33-like
, ADAM 33
, a disintegrin and metalloprotease domain 33
, a disintegrin and metalloprotease domain 13
, x-adam 13
, a disintegrin and metalloprotease 33
, a disintegrin and metalloproteinase domain 33
, disintegrin and reprolysin metalloproteinase family protein
, a disintegrin and metallopeptidase domain 33