anti-2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) Antikörper

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).. Zusätzlich bieten wir Ihnen Cnpase Kits (13) und Cnpase Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CNP 1267 P09543
CNP 12799 P16330
CNP 25275 P13233
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Top anti-Cnpase Antikörper auf antikoerper-online.de

Showing 10 out of 142 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-CNP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Fetal Muscle Immunohistochemistry with Brain, cortex tissue at an antibody concentration of 5µg/ml using anti-CNP antibody (ARP33879_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CNPase expression in rat  brain extract ( Lane 1), mouse brain extract ( Lane 2) and HELA whole cell lysates ( Lane 3). CNPase at 47KD was detected using rabbit anti- CNPase Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, WB WB Suggested Anti-CNP Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate CNP is supported by BioGPS gene expression data to be expressed in Jurkat Lanes:   1. Human NT-2 cells (60ug) lysate 2. Rat brain extract (80ug)  Primary Antibody Dilution:   2ug/ml  Secondary Antibody:   IRDye 800CW goat anti-rabbit from Li-COR Bioscience  Secondary Antibody Dilution:   1: 20,000  Gene Name:   CNP  Submitted by:   Dr. Yuzhi Chen, University of Arkansas for Medical Science 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of CNPase expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry: CNPase Antibody (2871) [NBP2-46635] - Analysis of rat hippocampus shows moderate immunoreactivity in single oligodendrocytes. Western Blot: CNPase Antibody (2871) [NBP2-46635] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Mouse Cerebral Cortex tissue 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-CNP/CNPase Polyclonal Antibody (ABIN730738), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$329.45
Details
Human Maus Unkonjugiert ICC, IF, WB Western Blot: CNPase Antibody (1H10) [NBP2-50031] - Analysis of rat brain tissue homogenates probed with NBP2-50031 at 1:5,000 (lane 1) and 1:20,000 (lane 2). The antibody binds strongly and cleanly to a band at ~48kDa. Immunocytochemistry/Immunofluorescence: CNPase Antibody (1H10) [NBP2-50031] - Mixed neuron-glial cell cultures stained with NBP2-50031 (red) and polyclonal antibody against GFAP (green, ABIN4299369). NBP2-50031 stains strongly in oligodendrocytes, whereas GFAP labels only the intermediate filaments in astrocytes. Blue is DNA staining. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$418.10
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using CNPase Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Pferd Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$493.17
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Anti-CNP antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958964 concentration 5 ug/ml. Anti-CNP antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Othe ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details

Am meisten referenzierte anti-Cnpase Antikörper

  1. Human Polyclonal Cnpase Primary Antibody für IF (p), IHC (p) - ABIN730738 : Li, Tang, Cai, Qiu, Lin, Zhu, Owusu, Guo: CNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan. in World journal of gastroenterology : WJG 2015 (PubMed)

  2. Human Polyclonal Cnpase Primary Antibody für WB - ABIN4886542 : Cai, Ma, Li, Tian, Li: Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway. in International journal of biological sciences 2017 (PubMed)

  3. Human Polyclonal Cnpase Primary Antibody für WB - ABIN6678410 : Hu, Xia, Wu, Li, Qi, Hu, Wei, Li, Tian, Wei, Shen, Yin, Jiang, Yuan, Qiang, Han, Peng: NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma. in Oncogene 2017 (PubMed)

Weitere Antikörper gegen Cnpase Interaktionspartner

Human 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) Interaktionspartner

  1. This study showed that the expression of CNPase protein was significantly decreased but increase expression mrna in ventral prefrontal white matter in major depressive disorder.

  2. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

  3. 2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.

  4. No Alzheimer disease-associated differences in CNP and DPYSL2 promoter DNA methylation were observed.

  5. CNP binds to the structural protein Gag and blocks HIV-1 particle assembly after Gag and viral RNA have associated with the plasma membrane.

  6. Bipolar I disorder and schizophrenia ahare a number of common genetic risk loci and susceptibility genes including the genes coding for 2',3'-cyclic nucleotide 3' phosphodiesterase enzyme.

  7. Differential CNP expression correlated with mouse model survival, and CNP immunoassay of a large GBM tissue microarray also showed significant differential patient survival

  8. The characteristic features in both humans and mice with their partial CNP 'loss-of-function' genotype are best described as 'catatonia-depression' syndrome.

  9. verified the molecular interaction of Nogo-A with 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which could act as a conformational stabilizer for the intrinsically unstructured large segment of Amino-Nogo

  10. crystal structure of 2',3'-cyclic nucleotide 3'-phosphohydrolase

  11. crystal structure of the catalytic fragment

  12. reduced CNP expression in the schizophrenic brain is relevant to disease etiology and therefore provide support for the general hypothesis that altered oligodendrocyte function is an etiological factor in schizophrenia.

  13. The crystal structure of the catalytic fragment of human CNP (hCNP-CF) at 1.3 A resolution, is determined.

  14. study did not find an association between genetic variations in the CNP gene and schizophrenia in the Han Chinese population

  15. MOBP and CNP protein in the white matter was not altered.

  16. The effect of rs2070106 genotype on the CNP expression was transcript specific, and that the genotype was not associated with the expression of other oligodendrocyte-related genes.

  17. This finding provides support for potential association of the CNP gene but not the MAG gene in schizophrenia in a Caucasian population.

  18. Almost all multiple sclerosis patients had cerebrospinal fluid IgG directed to isoforms of one of the oligodendroglial molecules, transketolase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, collapsin response mediator protein 2, and tubulin beta4.

  19. The results suggest that the CNP gene may not be involved in the etiology and pathology of schizophrenia in the Chinese population

  20. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia

Mouse (Murine) 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) Interaktionspartner

  1. The results of this study suggested that with an appropriate reporter system Cnp activity can be used to define a proliferative subpopulation of NG2 cells committed to generate oligodendrocytes.

  2. CNP directly associates with and organizes the actin cytoskeleton, thereby providing an intracellular strut that counteracts membrane compaction by myelin basic protein (MBP).

  3. Data show atomic-resolution details of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain active site.

  4. These data provide detailed novel insight into the complex effects of natriuretic peptides and their receptors on electrical conduction in the heart.

  5. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

  6. The data of this study reveal that CNPase is a critically important enzyme in the 2',3'-cAMP-adenosine pathway and participates in the production of adenosine, a protective neuromodulator.

  7. Low levels of Cnp1 seen in major depressive disorder (MDD) may cause unsustainable and maladaptive molecular compensations. contributing to the disease pathophysiology.

  8. The results indicate a role for the N-terminal domain of CNPase in mediating multiple molecular interactions and provide a starting point for detailed structure-function studies on CNPase and its N-terminal domain.

  9. analysis of myelin 2',3'-cyclic nucleotide 3'-phosphodiesterase active-site ligand binding and molecular conformation

  10. The downregulation of CNPase expression in the brain may be a possible consequence of Mecp2 gene mutation

  11. while OECs do not normally form myelin on olfactory nerve axons, their expression of CNPase is commensurate with their potential to form myelin when transplanted into injured peripheral nerve

  12. The results of this study showed that CNP::EGFP mice were significantly more susceptible to CPZ-induced demyelination, as evaluated by MBP immunostaining, oligodendroglial progenitor cell recruitment and astroglial, microglial and nestin response.

  13. Regulation of the Cnp gene, along with the relative amount of expressed Cnp enzyme, suggests that the immortalized cell lines containing them are representative of immature oligodendrocytes.

  14. Cnp1, which encodes 2',3'-cyclic nucleotide phosphodiesterase in oligodendrocytes, is essential for axonal survival but not for myelin assembly

  15. We suggest that CNP is a glial protein required for maintaining the integrity of paranodes and that disrupted axoglial signaling at this site underlies progressive axonal degeneration, observed later in the CNS of Cnp1-null mice.

  16. CNP is an important component of the cytoskeletal machinery that directs process outgrowth in Oligodendrocytes.

  17. Cyclic nucleotide phosphodiesterase 1 (PDE1)is involved in the regulation of duodenal HCO(3)(-) secretion and the response to pde(2) is associated with both PDE1 and PDE3, while the response to nitric oxide is mainly modulated by PDE1.

  18. We show that CNP is necessary for the formation of a normal inner tongue process of oligodendrocytes that myelinate small diameter axons. We also show that axonal degeneration in Cnp1 null mice is present very early in postnatal life.

Zebrafish 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) Interaktionspartner

  1. mutant versions of zebrafish RICH proteins were generated to study the roles of the domains of the protein at biochemical and cellular levels.

Cnpase (CNP) Antigen-Profil

Protein Überblick

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).

Genbezeichner und Symbole assoziert mit CNP

  • 2',3'-cyclic nucleotide 3' phosphodiesterase (CNP) Antikörper
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (Cnp) Antikörper
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (cnp) Antikörper
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (cnp.L) Antikörper
  • cnp Antikörper
  • Cnp-1 Antikörper
  • Cnp1 Antikörper
  • CNPase Antikörper
  • CNPF Antikörper
  • CNPI Antikörper
  • CNPII Antikörper
  • cnpl Antikörper
  • DKFZp469F1421 Antikörper
  • fd21d08 Antikörper
  • fi37a10 Antikörper
  • rich Antikörper
  • sb:cb662 Antikörper
  • si:ch73-158e11.4 Antikörper
  • wu:fd21d08 Antikörper
  • wu:fd44a05 Antikörper
  • wu:fi35d08 Antikörper
  • wu:fi37a10 Antikörper

Bezeichner auf Proteinebene für CNP

2', 3' cyclic nucleotide 3' phosphohydrolase , 2',3'-cyclic-nucleotide 3'-phosphodiesterase , CNPase , cyclic nucleotide phosphodiesterase 1 , CNP2 , 2',3'-cyclic nucleotide 3' phosphodiesterase , cyclic-CMP phosphodiesterase , 2', 3'-cyclic nucleotide phosphodiesterase , 2',3'-cyclic-nucleotide 3'-phosphodiesterase-like

GENE ID SPEZIES
1267 Homo sapiens
12799 Mus musculus
25275 Rattus norvegicus
280752 Bos taurus
395921 Gallus gallus
454673 Pan troglodytes
607694 Canis lupus familiaris
641337 Macaca mulatta
100171506 Pongo abelii
325896 Danio rerio
100467749 Ailuropoda melanoleuca
100595130 Nomascus leucogenys
101120423 Ovis aries
444056 Xenopus laevis
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