anti-Schwein Retinoblastoma Binding Protein 8 Antikörper für Western Blotting

Recommended Retinoblastoma Binding Protein 8 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Retinoblastoma Binding Protein 8 (RBBP8) Antikörper
  • COM1
  • CTIP
  • JWDS
  • RIM
  • SAE2
  • SCKL2
  • 9930104E21Rik
  • CtIP
  • RBBP-8
  • RGD1308872
  • RBBP8
  • DKFZp469K0714
  • RB binding protein 8, endonuclease
  • retinoblastoma binding protein 8, endonuclease
  • retinoblastoma binding protein 8 L homeolog
  • retinoblastoma binding protein 8
  • RBBP8
  • Rbbp8
  • rbbp8.L
  • rbbp8
Epitop
C-Term
12
9
8
8
5
5
5
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Schwein, Kaninchen
106
51
16
6
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
85
21
Klonalität
Polyklonal
Konjugat
Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
86
39
24
23
22
21
15
13
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2784374
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1929516 IP PLA WB Rabbit IgG AA 850-897, C-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Retinoblastoma Binding Protein 8 (RBBP8) Antikörper
Epitop C-Term
(12), (9), (8), (8), (5), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Schwein, Kaninchen
(106), (51), (16), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(85), (21)
Klonalität
Polyklonal
Konjugat Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert
(3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(86), (39), (24), (23), (22), (21), (15), (13), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Target Details Retinoblastoma Binding Protein 8 Anwendungsinformationen Handhabung Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982713.
Sequenz ETVDMDCTLV SETVLLKMKK QEQKGEKSSN EERKMNDSLE DMFDRTTHEE
Homologie Cow: 79%, Dog: 86%, Guinea Pig: 83%, Horse: 79%, Human: 100%, Pig: 100%, Rabbit: 100%
Produktmerkmale This is a rabbit polyclonal antibody against RBBP8. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human RBBP8

Target Details Retinoblastoma Binding Protein 8

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374) Bilder zurück nach oben
Antigen
Andere Bezeichnung RBBP8 (RBBP8 Antibody Abstract)
Hintergrund RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Alias Symbols: CTIP, RIM, JWDS, SAE2, SCKL2
Protein Interaction Partner: LMO4, PIN1, LMO1, MDM2, BRCA1, RBL1, TMEM54, PRRG4, RGS17, IKBKG, IGFBP7, EEF1A1, CTBP2, CLU, MAP2K4, RAF1, RBL2, PCNA, ZNF350, NBN, UIMC1, PALB2, BARD1, SPEN, RAD50, CTBP1, RB1, UBC, FXR2, RBBP8, IKZF1, LIMS1, SIAH2, SIAH1, LMO2, WDYHV1, ATM, TGIF2, IKZF
Protein Size: 867
Molekulargewicht 98 kDa
Gen-ID 5932
NCBI Accession NM_203292, NP_976037
UniProt A6NKN2
Pathways Zellzyklus, DNA Reparatur

Anwendungsinformationen

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper Target Details Retinoblastoma Binding Protein 8 Handhabung Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 867 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper Target Details Retinoblastoma Binding Protein 8 Anwendungsinformationen Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374)

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper Target Details Retinoblastoma Binding Protein 8 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Chen, Nievera, Lee, Wu: "Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7713-20, 2008

Bilder

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper Target Details Retinoblastoma Binding Protein 8 Anwendungsinformationen Handhabung Referenzen für anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN2784374) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Retinoblastoma Binding Protein 8 (RBBP8) (C-Term) antibody (ABIN2784374) WB Suggested Anti-RBBP8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Retinoblastoma Binding Protein 8 (RBBP8) (C-Term) antibody (ABIN2784374) Sample type: 1. HCT116 lysate (50ug)
2. MCF7 lysate (50ug)
3. rCtIP (30n...
Western Blotting (WB) image for anti-Retinoblastoma Binding Protein 8 (RBBP8) (C-Term) antibody (ABIN2784374) Host: Rabbit
Target Name: RBBP8
Sample Tissue: Human Fetal Heart
...