anti-BTRC (BTRC) Antikörper

Bezeichnung:
anti-beta-Transducin Repeat Containing Antikörper (BTRC)
Auf www.antikoerper-online.de finden Sie aktuell 49 beta-Transducin Repeat Containing (BTRC) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BTRC Kits (14) und BTRC Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 69 BTRC Produkte verfügbar.
Synonyme:
b-TrCP, BETA-TRCP, Beta-Trcp1, betaTrCP, btrc, btrc-a, bTrCP, bTrCP1, Fbw1a, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, Slimb

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anti-Human BTRC Antikörper:

anti-Rat (Rattus) BTRC Antikörper:

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Am meisten referenzierte anti-BTRC Antikörper

  1. Human Polyclonal BTRC Primary Antibody für EIA, IF - ABIN952275 : Popov, Schülein, Jaenicke, Eilers: Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover. in Nature cell biology 2010 (PubMed)
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Weitere Antikörper gegen BTRC Interaktionspartner

Xenopus laevis beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. Strong ERK (zeige MAPK1 Antikörper) activation can target Cdc25A (zeige CDC25A Antikörper) for degradation in a manner similar to, but independent of, Chk1 (zeige CHEK1 Antikörper) for cell cycle arrest.

Human beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. It demonstrates that degradation of Lipin-1 (zeige LPIN1 Antikörper) is regulated by BTRC in the cytoplasm and on membranes

  2. we identified two independent SNPs (i.e., WNT2B (zeige WNT2B Antikörper) rs1175649 G>T and BTRC rs61873997 G>A) that showed a predictive role in CM-specific survival, with an effect-allele-attributed hazards ratio (adjusted hazards ratio) of 1.99 (95% confidence interval = 1.41-2.81, P = 8.10 x 10(-5)) and 0.61 (0.46-0.80, 3.12x10(-4)), respectively.

  3. It has been proposed that CENP-W (zeige CENPW Antikörper) may function as a booster of beta-TrCP1 nuclear import to increase the oncogenicity of beta-TrCP1.

  4. oncogenic effect of miR (zeige MLXIP Antikörper)-182 and its reversal by beta-TrCP2 were confirmed in vivo This study suggests that beta-TrCP and miR (zeige MLXIP Antikörper)-182 may be possible biomarkers and targets for early detection and treatment of pancreatic cancer

  5. Beta-TrCP controls ubiquitination and degradation of liver-enriched transcription factor CREB-H (zeige CREB3L3 Antikörper).

  6. Phosphorylated VEGFR-2 (zeige KDR Antikörper) was reduced by hyperglycemia while total VEGFR-2 (zeige KDR Antikörper) was almost unaltered. However, VEGFR-2 (zeige KDR Antikörper) was reduced when directly exposed to reactive oxygen species, with resultant co-location of beta-TrCP and VEGFR-2 (zeige KDR Antikörper).

  7. Low GAS7C increases cancer cell motility by promoting N-WASP (zeige WASL Antikörper)/FAK (zeige PTK2 Antikörper)/F-actin cytoskeleton dynamics. It also enhances beta-catenin (zeige CTNNB1 Antikörper) stability via hnRNP U (zeige HNRNPU Antikörper)/beta-TrCP complex formation.

  8. EBV-miR (zeige MLXIP Antikörper)-BART10-3p facilitated epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC.

  9. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  10. This study showed SCF (zeige KITLG Antikörper)(beta-TRCP) earmarks Set8 (zeige SETD8 Antikörper) for ubiquitination and degradation in a casein kinase I (zeige CSNK1D Antikörper)-dependent manner, which is activated by DNA-damaging agents.

Mouse (Murine) beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. betaTrCP levels are correlated with imiquimod-induced skin lesion.

  2. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  3. Erbin (zeige ERBB2IP Antikörper) as a novel substrate of SAG (zeige RNF7 Antikörper)-betaTrCP E3 ligase.

  4. these results clearly suggest that both beta-TrCP- and Hrd1 (zeige SYVN1 Antikörper)-dependent degradation mechanisms regulate the transcriptional activity of Nrf1 (zeige NRF1 Antikörper) to maintain cellular homeostasis.

  5. beta-TrCP may be an essential player in UVB induced responses in skin

  6. Glycogen synthase kinase 3 (zeige GSK3a Antikörper) phosphorylates a group of Ser (zeige SIGLEC1 Antikörper) residues in the Neh6 domain of mouse Nrf2 (zeige NFE2L2 Antikörper) that overlap with an SCF (zeige KITLG Antikörper)/beta-TrCP destruction motif (DSGIS, residues 334 to 338) and promotes its degradation in a Keap1 (zeige KEAP1 Antikörper)-independent manner.

  7. LPS (zeige TLR4 Antikörper) appears to destabilize the LPCAT1 (zeige LPCAT1 Antikörper) protein by GSK-3beta (zeige GSK3b Antikörper)-mediated phosphorylation within a canonical phosphodegron for beta-TrCP docking and site-specific ubiquitination.

  8. the two beta-TrCP paralogs have a nonredundant role in spermatogenesis

  9. anti-inflammatory effects of H(2)O(2) may result from its ability to decrease ubiquitination as well as subsequent degradation of I kappaB alpha through inhibiting the association between I kappaB alpha and SCF (zeige KITLG Antikörper)(beta-TrCP)

  10. BMP-2 (zeige BMP2 Antikörper) modulates beta-catenin (zeige CTNNB1 Antikörper) signaling through stimulation of Lrp5 (zeige LRP5 Antikörper) expression and inhibition of beta-TrCP expression in osteoblasts

BTRC Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class\; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

Alternative names and synonyms associated with BTRC

  • beta-transducin repeat containing (BTRC) Antikörper
  • beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) Antikörper
  • beta-transducin repeat containing E3 ubiquitin protein ligase (btrc) Antikörper
  • beta-transducin repeat containing (btrc) Antikörper
  • beta-transducin repeat containing E3 ubiquitin protein ligase (Btrc) Antikörper
  • beta-transducin repeat containing protein (Btrc) Antikörper
  • b-TrCP Antikörper
  • BETA-TRCP Antikörper
  • Beta-Trcp1 Antikörper
  • betaTrCP Antikörper
  • btrc Antikörper
  • btrc-a Antikörper
  • bTrCP Antikörper
  • bTrCP1 Antikörper
  • Fbw1a Antikörper
  • FBXW1 Antikörper
  • FBXW1A Antikörper
  • FWD1 Antikörper
  • HOS Antikörper
  • mKIAA4123 Antikörper
  • Slimb Antikörper

Bezeichner auf Proteinebene für BTRC

beta-transducin repeat containing , beta-transducin repeat containing protein , F-box/WD repeat-containing protein 1A , f-box/WD repeat-containing protein 1A-like , E3RSIkappaB , F-box and WD repeats protein beta-TrCP , F-box and WD-repeat protein 1B , beta-TrCP1 , epididymis tissue protein Li 2a , pIkappaBalpha-E3 receptor subunit , beta-TrCP , beta-transducin repeat-containing protein , SCF b-TRCP , beta-TrCP protein E3RS-IkappaB , mE3RS-IkappaB , pIkappaB-E3 receptor subunit , ubiquitin ligase FWD1

GENE ID SPEZIES
423854 Gallus gallus
450685 Pan troglodytes
486851 Canis lupus familiaris
534072 Bos taurus
549140 Xenopus (Silurana) tropicalis
100171847 Pongo abelii
100337561 Xenopus laevis
100470916 Ailuropoda melanoleuca
100157842 Sus scrofa
100634006 Amphimedon queenslandica
8945 Homo sapiens
361765 Rattus norvegicus
394362 Xenopus laevis
100350519 Oryctolagus cuniculus
100730107 Cavia porcellus
101101939 Ovis aries
12234 Mus musculus
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