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anti-Human RHOC Antikörper:
anti-Rat (Rattus) RHOC Antikörper:
anti-Mouse (Murine) RHOC Antikörper:
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Human Monoclonal RHOC Primary Antibody für ELISA, WB - ABIN513475
Han, Li, Hu, Yu, Zheng, Guo, Zheng, Yi, Zhou: Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation. in Endocrinology 2010
Human Monoclonal RHOC Primary Antibody für IF, ELISA - ABIN513476
Saito, Ohmasa, Shomori, Dimitriadis, Ohiwa, Shimizu, Tsounapi, Kinoshita, Satoh: Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions. in Molecular and cellular biochemistry 2011
Human Polyclonal RHOC Primary Antibody für ELISA, WB - ABIN559936
Han, Yang, Li, Li, Zheng, Yu, Zhang, Zheng, Yi, Li, Guo, Zhou: RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia. in Cell and tissue research 2016
Cow (Bovine) Polyclonal RHOC Primary Antibody für IHC, WB - ABIN2786344
Sousa, Espreafico: Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets. in BMC cancer 2008
Human Polyclonal RHOC Primary Antibody für IF (p), IHC (p) - ABIN687157
He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells. in Cellular signalling 2017
E2F transcription factor 1 (E2F1 (zeige E2F1 Antikörper)) downregulated micrRNA miR (zeige MLXIP Antikörper)-519d directly and miR (zeige MLXIP Antikörper)-519d downregulated Ras homolog gene family member C (RhoC) directly.
These results reveal a previously unidentified pathway downstream of RHO that regulates the polarity of migrating cells through Golgi reorientation in a FAM65A-, CCM3 (zeige PDCD10 Antikörper)- and MST3 (zeige STK24 Antikörper)- and MST4 (zeige MST4 Antikörper)-dependent manner.
During the process of epithelial-mesenchymal transition in A549 cells induced by TGF-beta1 (zeige TGFB1 Antikörper), upregulated RhoC protein and RhoC activity were detected, which was associated with the enhanced invasive capability of the cells in vitro.
RhoC downregulation may inhibit the proliferation, drug resistance, invasion and migration of ovarian cancer stem cells.
Downregulation of RHOC inhibited cholangiocellular carcinoma cells invasion and migration partially via inhibition of matrix metalloproteinase 2 (zeige MMP2 Antikörper), 3 and 9 expression. RHOC also modulated the expression of several epithelial-mesenchymal transition (EMT (zeige ITK Antikörper))-associated proteins
RT-PCR and Western blot assays demonstrated that miR (zeige MLXIP Antikörper)-372 transfection reduced the expression of RhoC.
Significant associations between ROCK1 (zeige ROCK1 Antikörper), ROCK2 (zeige ROCK2 Antikörper), RhoA (zeige RHOA Antikörper) and RhoC gene polymorphisms and systemic sclerosis were demonstrated.
study has identified several new proteins like RHOC, DLG5 (zeige DLG5 Antikörper), UGDH (zeige UGDH Antikörper), TMOD3 (zeige TMOD3 Antikörper) in addition to known chemoresistance associated proteins in non-small cell lung carcinoma.
the oncogene (zeige RAB1A Antikörper) RhoC, a driver of metastatic potential, modulates glutamine (zeige GFPT1 Antikörper) and N-acetylaspartate metabolism in Inflammatory Breast Cancer cells in vitro, revealing a novel role for RhoC as a regulator of tumor cell metabolism that extends beyond its well known role in cytoskeletal rearrangement.
The knockdown of RhoC protein decreased the proliferation rate of the parental and the IE1-expressing glioblastoma cells.
Inhibition of ovarian epithelial carcinoma tumorigenesis and progression by miR106b proceeds through the RhoC pathway.
RHOC and RAB38 (zeige RAB38 Antikörper) are dispensable for osteoclast function.
A p27(kip1 (zeige CDKN1B Antikörper))-binding protein, p27RF-Rho (zeige LAMTOR1 Antikörper), promotes cancer metastasis via activation of RhoA (zeige RHOA Antikörper) and RhoC.
We found that both RhoA and RhoC, but not RhoB, were required for initiation of centrosome duplication, and overactivation of RhoA, as well as RhoC, but not RhoB, promoted centrosome duplication and centrosome amplification.
RhoC has a role in metastasis of lung cancer in mice
loss of RhoC does not affect tumor development but decreases tumor cell motility and metastatic cell survival leading to a drastic inhibition of metastasis
RhoC promotes melanoma progression via separate mechanisms that regulate the PI3K/Akt (zeige AKT1 Antikörper) pathway and the ROCK signaling pathway.
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
ras homolog gene family, member C
, rho-related GTP-binding protein RhoC
, RAS-related homolog 9
, oncogene RHO H9
, rho cDNA clone 9
, rhoC GTPase
, small GTP binding protein RhoC
, aplysia ras-related homolog 9 (RhoC)
, ras homolog 9 (RhoC)
, silica-induced gene 61 protein
, GTP-binding protein
, GTPase cRhoC