anti-Maus Phospholipase C beta 1 Antikörper für Immunofluorescence

Recommended Phospholipase C beta 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) Antikörper
  • PLCB1
  • 3110043I21Rik
  • AI132408
  • Plcb
  • mKIAA0581
  • EIEE12
  • PI-PLC
  • PLC-154
  • PLC-I
  • PLC154
  • PLCB1A
  • PLCB1B
  • PLC'1
  • PLCbeta1
  • Phosphb
  • RATPHOSPHB
  • phospholipase C, beta 1 (phosphoinositide-specific)
  • phospholipase C, beta 1
  • PLCB1
  • plcb1
  • Plcb1
Epitop
AA 4-159
16
4
3
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
54
39
37
6
4
4
4
3
2
2
1
1
Wirt
Maus
52
3
1
Klonalität
Monoklonal
Konjugat
Dieser Phospholipase C beta 1 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
33
16
13
11
7
4
3
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN968253
146,73 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.326117 ABIN1874160 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
12.326117 ABIN2404874 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2880009 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

anti-Phospholipase C beta 1 Antikörper für Immunofluorescence mit den meisten Publikationen

Ähnliche anti-Phospholipase C beta 1 Antikörper

Applikation / Reaktivität Human Maus Ratte (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antikörper 1 Antikörper 1 Antikörper
Western Blotting (WB) 32 Antikörper 22 Antikörper 20 Antikörper
Immunoprecipitation (IP) 2 Antikörper 1 Antikörper 1 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antikörper 7 Antikörper 7 Antikörper
Immunohistochemistry (IHC) 12 Antikörper 12 Antikörper 16 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper 13 Antikörper 13 Antikörper
Immunofluorescence (IF) 5 Antikörper 4 Antikörper

General

Antigen phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) Antikörper
Epitop AA 4-159
(16), (4), (3), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(54), (39), (37), (6), (4), (4), (4), (3), (2), (2), (1), (1)
Wirt Maus
(52), (3), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Phospholipase C beta 1 Antikörper ist unkonjugiert
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(33), (16), (13), (11), (7), (4), (3), (2), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Phospholipase C beta 1 Antikörper

Target Details Phospholipase C beta 1 Anwendungsinformationen Handhabung ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253) Bilder
Kreuzreaktivität Human, Maus
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Rat Phospholipase Cbeta1 aa. 4-159
Klon 16-Phospholipase Cbeta1
Isotyp IgG1

Target Details Phospholipase C beta 1

Produktdetails anti-Phospholipase C beta 1 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253) Bilder zurück nach oben
Antigen
Andere Bezeichnung Phospholipase C beta 1 (PLCB1 Antibody Abstract)
Hintergrund Phospholipase C (PLC) hydrolyzes inositol phospholipids into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). The former causes release of Ca2+ from intracellular stores, while the latter is an activator of PKC. At least three isozymes are known: PLCbeta, PLCgamma, and PLCdelta. They recognize phosphatidylinositol (PI), phosphatidylinositol 4-phosphate (PIP2), and phospatidylinositol 4,5 bisphosphate (PIP2) and carry out the Ca2+-dependent hydrolysis of these inositol phospholipids. All three classes contain two highly conserved regions, designated X” and Y”, whose structural integrity is essential for a functional catalytic core. The PLCbeta subfamily has been reported to contain at least four members: beta1, beta2, beta3 and beta4. PLCbeta1 has been reported to have been identified and cloned from brain tissue where the PLCbeta1 gene encodes for two different mRNAs. The resulting protein products, PLCbeta1a (121 aa) and PLCbeta1b (1173 aa) differ only at their C-termini. Although PLCgamma activity is induced by receptor tyrosine kinase phosphorylation, PLCbeta is regulated by G protein alpha subunits or betagamma subunits. In particular, Galphaq has been reported to activate PLCbeta1. This antibody is routinely tested by western blot analysis.
Synonyms: PLCbeta1
Molekulargewicht 150 kDa
Pathways WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events

Anwendungsinformationen

Produktdetails anti-Phospholipase C beta 1 Antikörper Target Details Phospholipase C beta 1 Handhabung ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253) Bilder zurück nach oben
Kommentare

Related Products: ABIN968545, ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Phospholipase C beta 1 Antikörper Target Details Phospholipase C beta 1 Anwendungsinformationen ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20° C.

ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253)

Produktdetails anti-Phospholipase C beta 1 Antikörper Target Details Phospholipase C beta 1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Avazeri, Courtot, Pesty, Duquenne, Lefèvre: "Cytoplasmic and nuclear phospholipase C-beta 1 relocation: role in resumption of meiosis in the mouse oocyte." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4369-80, 2000

Bahk, Lee, Lee, Seo, Ryu, Suh: "Two forms of phospholipase C-beta 1 generated by alternative splicing." in: The Journal of biological chemistry, Vol. 269, Issue 11, pp. 8240-5, 1994

Rhee, Choi: "Regulation of inositol phospholipid-specific phospholipase C isozymes." in: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 12393-6, 1992

Suh, Ryu, Moon, Suh, Rhee: "Cloning and sequence of multiple forms of phospholipase C." in: Cell, Vol. 54, Issue 2, pp. 161-9, 1988

Bilder

Produktdetails anti-Phospholipase C beta 1 Antikörper Target Details Phospholipase C beta 1 Anwendungsinformationen Handhabung ProductDetails: References for anti-Phospholipase C beta 1 antibody (ABIN968253) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Phospholipase C beta 1 Antikörper (phospholipase C, beta 1 (phosphoinositide-Specific)) (AA 4-159) (ABIN968253) Western blot analysis of Phospholipase Cbeta1 on a rat cerebrum lysate. Lane 1: 1: 10...
Immunofluorescence (IF) image for anti-Phospholipase C beta 1 Antikörper (phospholipase C, beta 1 (phosphoinositide-Specific)) (AA 4-159) (ABIN968253) Immunofluorescence staining of human intestinal smooth muscle cells (HISM).
 image for anti-Phospholipase C beta 1 Antikörper (phospholipase C, beta 1 (phosphoinositide-Specific)) (AA 4-159) (ABIN968253) anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) (AA 4-159) antibody (Image 3)
Western Blotting (WB) image for anti-Phospholipase C beta 1 Antikörper (phospholipase C, beta 1 (phosphoinositide-Specific)) (AA 4-159) (ABIN968253) anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) (AA 4-159) antibody (Image 4)