anti-Rind (Kuh) FZD4 Antikörper für Western Blotting

Recommended FZD4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Frizzled Family Receptor 4 (FZD4) Antikörper
  • CG4626
  • DFz4
  • Dfz4
  • Dm Fz4
  • Dmel\\CG4626
  • Fz4
  • anon-WO0170980.10
  • anon-WO0170980.11
  • fz1
  • zg01
  • CD344
  • EVR1
  • FEVR
  • FZD4S
  • Fz-4
  • FzE4
  • GPCR
  • hFz4
  • frizzled4
  • fz4
  • FZ-4
  • frizzled 4
  • frizzled homolog 4
  • frizzled-4
  • frizzled family receptor 4
  • frizzled homolog 4 (Drosophila)
  • fz4
  • fzd4
  • Tsp_10376
  • FZD4
  • Fzd4
Epitop
Middle Region
27
22
18
15
13
10
9
8
4
4
4
3
3
3
2
2
1
1
1
Reaktivität
Rind (Kuh), Meerschweinchen, Pferd, Human, Maus, Ratte (Rattus)
141
107
52
7
7
7
7
5
5
5
5
4
2
2
2
1
Wirt
Kaninchen
99
35
25
8
Klonalität
Polyklonal
Konjugat
Dieser FZD4 Antikörper ist unkonjugiert
10
8
5
5
5
4
4
4
4
4
4
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
95
52
38
15
13
12
12
9
4
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2776715
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN768861 IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN303859 ELISA WB Goat AA 39-51 Anmelden zum Anzeigen Polyclonal
1 ABIN1836957 WB Rabbit AA 280-329 Anmelden zum Anzeigen Polyclonal

General

Antigen Frizzled Family Receptor 4 (FZD4) Antikörper
Epitop Middle Region
(27), (22), (18), (15), (13), (10), (9), (8), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1)
Reaktivität Rind (Kuh), Meerschweinchen, Pferd, Human, Maus, Ratte (Rattus)
(141), (107), (52), (7), (7), (7), (7), (5), (5), (5), (5), (4), (2), (2), (2), (1)
Wirt Kaninchen
(99), (35), (25), (8)
Klonalität
Polyklonal
Konjugat Dieser FZD4 Antikörper ist unkonjugiert
(10), (8), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(95), (52), (38), (15), (13), (12), (12), (9), (4), (2), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FZD4 Antikörper

Target Details FZD4 Anwendungsinformationen Handhabung Referenzen für anti-FZD4 Antikörper (ABIN2776715) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977169.
Sequenz GITSGMWIWS AKTLHTWQKC SNRLVNSGKV KREKRGNGWV KPGKGSETVV
Homologie Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against FZD4. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FZD4

Target Details FZD4

Produktdetails anti-FZD4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FZD4 Antikörper (ABIN2776715) Bilder zurück nach oben
Antigen
Andere Bezeichnung FZD4 (FZD4 Antibody Abstract)
Hintergrund FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, CD344
Protein Interaction Partner: UBC, NDP, ZNRF3, BAG6, MAGI3, DLG2, DLG4, DVL2, DLG1, ARRB2,
Protein Size: 537
Molekulargewicht 60 kDa
Gen-ID 8322
NCBI Accession NM_012193, NP_036325
UniProt Q9ULV1
Pathways WNT Signalweg, Hormone Transport, Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Handhabung Referenzen für anti-FZD4 Antikörper (ABIN2776715) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 537 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Anwendungsinformationen Referenzen für anti-FZD4 Antikörper (ABIN2776715) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FZD4 Antikörper (ABIN2776715)

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Wang, Pawlak, Johnson, Belknap, Eades, Stack, Cousin, Black: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, 2013

McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, 2012

Gonzalez, Fernandez-Martos, Gonzalez-Fernandez, Arenas, Rodriguez: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." in: PLoS ONE, Vol. 7, Issue 12, pp. e50793, 2012

Allgemeine Veröffentlichungen

Dufourcq, Leroux, Ezan, Descamps, Lamazière, Costet, Basoni, Moreau, Deutsch, Couffinhal, Duplàa: "Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation." in: The American journal of pathology, Vol. 172, Issue 1, pp. 37-49, 2008

Bilder

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Anwendungsinformationen Handhabung Referenzen für anti-FZD4 Antikörper (ABIN2776715) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Frizzled Family Receptor 4 (FZD4) (Middle Region) antibody (ABIN2776715) anti-Frizzled Family Receptor 4 (FZD4) (Middle Region) antibody