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there was a strong inverse correlation between nuclear immunostaining scores for beta-catenin (zeige CTNNB1 ELISA Kits) expression and expression patterns of FZD10
FZD10 transactivation causes the activation of the Dvl (zeige DVL2 ELISA Kits)-Rac1-JNK (zeige MAPK8 ELISA Kits) pathway and is associated with the development/progression of synovial sarcomas
Data demonstrate that Wnt7b (zeige WNT7B ELISA Kits) signals through Fzd1 (zeige Fzd1 ELISA Kits) and -10 and LRP5 (zeige LRP5 ELISA Kits) and implicate these Wnt (zeige WNT2 ELISA Kits) coreceptors in the regulation of lung airway and vascular development.
Interprets Wnt (zeige WNT2 ELISA Kits) signals during embryonic mesoderm and neural induction.
Frizzled10 expression is very strong during embryonic development of the CNS and may play an essential role in spatial and temporal regulation during neural development.
Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development.
Results suggest that Frizzed 10 mediates Wnt1 (zeige WNT1 ELISA Kits) signalling to determine sensory neural differentiation in Xenopus in vivo and in mouse cell culture.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
, frizzled homolog 3
, frizzled homolog 10
, frizzled 10, seven transmembrane spanning receptor
, seven transmembrane spanning receptor
, frizzled homolog 4
, frizzled homolog B