anti-Human CAMK2G Antikörper für Immunohistochemistry

Recommended CAMK2G Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) Antikörper
  • cam2
  • camk2
  • camk2g
  • camkII
  • camkb
  • CaMKII
  • R74975
  • mKIAA0968
  • CAMK
  • CAMK-II
  • CAMKG
  • 5930429P18Rik
  • Camkg
  • calcium/calmodulin-dependent protein kinase II gamma
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II beta
  • calcium/calmodulin-dependent protein kinase II alpha
  • CAMK2G
  • camk2b
  • Camk2a
  • Camk2g
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
107
75
73
20
3
3
3
2
2
2
1
1
1
1
Wirt
Maus
70
47
Klonalität
Monoklonal
Konjugat
Dieser CAMK2G Antikörper ist konjugiert mit PE-Atto 594
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Radioimmunoassay (RIA), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
112
64
62
52
40
39
17
7
3
3
1
1
1
1
1
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Bilder

Produktnummer ABIN2484562
$ 420.20
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
8.868737 ABIN2484913 ICC IF IP IHC ELISA WB Atto 633 Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484549 ICC IF IP RIA IHC ELISA WB Atto 390 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484550 ICC IF IP RIA IHC ELISA WB Atto 488 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484551 ICC IF IP RIA IHC ELISA WB Atto 565 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484553 ICC IF IP RIA IHC ELISA WB Atto 633 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484556 ICC IF IP RIA IHC ELISA WB Atto 700 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484555 ICC IF IP RIA IHC ELISA WB Atto 680 Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484557 ICC IF IP RIA IHC ELISA WB Alkaline Phosphatase (AP) Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484559 ICC IF IP RIA IHC ELISA WB Biotin Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484560 ICC IF IP RIA IHC ELISA WB FITC Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484563 ICC IF IP RIA IHC ELISA WB PerCP Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484561 ICC IF IP RIA IHC ELISA WB HRP Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484564 ICC IF IP RIA IHC ELISA WB PE Mouse IgG1 Anmelden zum Anzeigen 6G9 2
8.868737 ABIN2484915 ICC IF IP IHC ELISA WB Atto 680 Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484914 ICC IF IP IHC ELISA WB Atto 655 Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484916 ICC IF IP IHC ELISA WB Atto 700 Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484920 ICC IF IP IHC ELISA WB FITC Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484919 ICC IF IP IHC ELISA WB Biotin Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484921 ICC IF IP IHC ELISA WB HRP Mouse IgG1 Anmelden zum Anzeigen 22B1 2
8.868737 ABIN2484922 ICC IF IP IHC ELISA WB PE-Atto 594 Mouse IgG1 Anmelden zum Anzeigen 22B1 2

General

Antigen Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) Antikörper
Reaktivität Rind (Kuh), Human, Maus, Ratte (Rattus)
(107), (75), (73), (20), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Wirt Maus
(70), (47)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CAMK2G Antikörper ist konjugiert mit PE-Atto 594
(3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Radioimmunoassay (RIA), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(112), (64), (62), (52), (40), (39), (17), (7), (3), (3), (1), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CAMK2G Antikörper

Target Details CAMK2G Anwendungsinformationen Handhabung Referenzen für anti-CAMK2G Antikörper (ABIN2484562) Bilder
Spezifität Detects ~50-60 kDa. Recognizes both phosphorylated and non-phosphorylated forms.
Reinigung Protein G Purified
Immunogen Partially purified rat CaMKII
Klon 6G9
Isotyp IgG1

Target Details CAMK2G

Produktdetails anti-CAMK2G Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CAMK2G Antikörper (ABIN2484562) Bilder zurück nach oben
Antigen
Andere Bezeichnung CaMKII (CAMK2G Antibody Abstract)
Hintergrund CaMKII is an important member of the calcium/calmodulin-activated protein kinase family, functioning in neural synaptic stimulation and T-cell receptor signaling (1, 2). CaMKII is expressed in many different tissues but is specifically found in the neurons of the forebrain and its mRNA is found within the dendrites and the soma of the neuron. The CaMKII that is found in the neurons consist of two subunits of 52 (termed alpha genes) and 60 kDa (beta genes). CaMKII has catalytic and regulatory domains, as well as an ATP-binding domain, and a consensus phosphorylation site (3-7). The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase (8). This kinase activation results in autophosphorylation at threonine 286 (8). The threonine phosphorylation state of CaMKII can be regulated through PP1/PKA. Whereas PP1 (protein phosphatase 1) dephosphorylates phospho-CaMKII at Thr286, PKA (protein kinase A) prevents this dephosphorylation (9). Autophosphorylation also enables CaMKII to attain an enhanced affinity for NMDA receptors in postsynaptic densities (10-12).
Gen-ID 12322
NCBI Accession NP_033922
UniProt P11798
Forschungsgebiet Cancer, Hypertrophy, Kinases/Phosphatases
Pathways WNT Signalweg, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity

Anwendungsinformationen

Produktdetails anti-CAMK2G Antikörper Target Details CAMK2G Handhabung Referenzen für anti-CAMK2G Antikörper (ABIN2484562) Bilder zurück nach oben
Applikationshinweise
  • WB (1:10000)
  • IHC (1:2000)
  • ICC/IF (1:50)
  • optimal dilutions for assays should be determined by the user.
Kommentare

0.1 μg/ml was sufficient for detection of CamKII in 20 μg rat brain tissue extract by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:AP as the secondary.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CAMK2G Antikörper Target Details CAMK2G Anwendungsinformationen Referenzen für anti-CAMK2G Antikörper (ABIN2484562) Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C

Referenzen für anti-CAMK2G Antikörper (ABIN2484562)

Produktdetails anti-CAMK2G Antikörper Target Details CAMK2G Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Shen, Meyer: "Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation." in: Science (New York, N.Y.), Vol. 284, Issue 5411, pp. 162-6, 1999

Tombes, Krystal: "Identification of novel human tumor cell-specific CaMK-II variants." in: Biochimica et biophysica acta, Vol. 1355, Issue 3, pp. 281-92, 1997

Bilder

Produktdetails anti-CAMK2G Antikörper Target Details CAMK2G Anwendungsinformationen Handhabung Referenzen für anti-CAMK2G Antikörper (ABIN2484562) zurück nach oben
Bilder des Herstellers
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (PE-Atto 594) (ABIN2484562) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-CaMKII Monoclonal An...
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (PE-Atto 594) (ABIN2484562) Western Blot analysis of Rat brain membrane lysate showing detection of CaMKII protei...
Immunohistochemistry (IHC) image for anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (PE-Atto 594) (ABIN2484562) Immunohistochemistry analysis using Mouse Anti-CaMKII Monoclonal Antibody, Clone 6G9 ...
Immunohistochemistry (IHC) image for anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (PE-Atto 594) (ABIN2484562) Immunohistochemistry analysis using Mouse Anti-CaMKII Monoclonal Antibody, Clone 6G9 ...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (PE-Atto 594) (ABIN2484562) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-CaMKII Monoclonal An...