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Human Polyclonal ZEB2 Primary Antibody für IHC, IHC (p) - ABIN4366808
Cai, Luo, Chen, Pei, Lu, Hou, Yun: Overexpression of ZEB2 in peritumoral liver tissue correlates with favorable survival after curative resection of hepatocellular carcinoma. in PLoS ONE 2012
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Cow (Bovine) Polyclonal ZEB2 Primary Antibody für IHC, WB - ABIN2780948
Verstappen, van Grunsven, Michiels, Van de Putte, Souopgui, Van Damme, Bellefroid, Vandekerckhove, Huylebroeck: Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex. in Human molecular genetics 2008
Show all 4 Pubmed References
Human Polyclonal ZEB2 Primary Antibody für IHC (p), WB - ABIN317804
He, Xiao, Zhang, Ma, Li, Yang: Detection and functional annotation of misregulated microRNAs in the brain of the Ts65Dn mouse model of Down syndrome. in Chinese medical journal 2013
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Human Polyclonal ZEB2 Primary Antibody für IHC, ELISA - ABIN1533518
Harada, Miyake, Kusuda, Fujisawa: Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy. in BJU international 2012
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Human Monoclonal ZEB2 Primary Antibody für IF, ELISA - ABIN523264
Pogribny, Muskhelishvili, Tryndyak, Beland: The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation. in Toxicology and applied pharmacology 2009
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Human Monoclonal ZEB2 Primary Antibody für IF, WB - ABIN395497
Minn, Lee, Hyung, Kim, Choi, Yang, Song, Lim, Kim: MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma. in International journal of oncology 2014
Human Polyclonal ZEB2 Primary Antibody für WB - ABIN523261
Kumar, Kotlyarevska, Dejkhmaron, Reddy, Lu, Bhojani, Menon et al.: Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for ... in The Journal of biological chemistry 2010
Human Polyclonal ZEB2 Primary Antibody für ELISA, ICC - ABIN4366807
Xu, Zhu, Zhao, Chen, Zhang, Yuan, Deng, Dou, Wang, Huang, Chen, Jiang, Yu: Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. in Oncotarget 2015
The Ppa (zeige FBXL14 Antikörper) could also target the third core EMT (zeige ITK Antikörper) regulatory factor Sip1 (zeige GEMIN2 Antikörper) for proteasomal degradation.
Simultaneous knockdown of both ZEB1 (zeige ZEB1 Antikörper) and ZEB2 expression establishes ZEB1 (zeige ZEB1 Antikörper) as a transcriptional repressor of E-cadherin (zeige CDH1 Antikörper) and a driver of docetaxel resistance in docetaxel-resistant prostate cancer cells.
Study demonstrate that CdGAP (zeige ARHGAP31 Antikörper) acts as a novel co-transcriptional repressor with Zeb2 to suppress E-cadherin (zeige CDH1 Antikörper) expression in breast cancer cells.
siRNAs targeting Ets1 (zeige ETS1 Antikörper) repressed expression of ZEB1 (zeige ZEB1 Antikörper)/ZEB2.
overexpression of miR (zeige MLXIP Antikörper)-218 in H1299 increased chemosensitivity of cells to cisplatin treatment through suppression of Slug (zeige SNAI2 Antikörper) and ZEB2. These findings highlight an important role of miR (zeige MLXIP Antikörper)-218 in the regulation of EMT (zeige ITK Antikörper)-related traits and metastasis of lung cancer in part by modulation of Slug (zeige SNAI2 Antikörper)/ZEB2 signaling, and provide a potential therapeutic strategy by targeting miR (zeige MLXIP Antikörper)-218 in lung cancer.
results revealed the critical regulatory role of miR (zeige MLXIP Antikörper)-145 in hepatic stellates cells activation and implied miR (zeige MLXIP Antikörper)-145 as a potential candidate for therapy of hepatic fibrosis by regulation of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) through targeting ZEB2
Results show that inhibition of miR (zeige MLXIP Antikörper)-141 enhanced colorectal cancer (CRC (zeige CALR Antikörper)) cell proliferation and migration through significant increase of its target's expression, ZEB2 and phosphorylation of HGFR.
This Gene-based tests suggest evidence of association with related genes, ZEB2, RND3 (zeige RND3 Antikörper), MCTP1, CTBP2 (zeige CTBP2 Antikörper), and beta EEG.
Collectively, the results demonstrate that Zeb2 controls adult hematopoietic differentiation and lineage fidelity through widespread modulation of dominant signaling pathways that may contribute to blood disorders.
ZEB2 transcriptionally represses genes that regulate myeloid differentiation, including genes involved in cell adhesion and migration; epigenetic silencing of the miR (zeige MLXIP Antikörper)-200 family microRNAs affects ZEB2 expression.
This study identified the lysine-specific demethylase (zeige MBD2 Antikörper) KDM1A (zeige KDM1A Antikörper) as a novel interaction partner of ZEB2 and demonstrated that mouse and human T-cell acute lymphoblastic leukemia cells with increased ZEB2 levels critically depend on KDM1A (zeige KDM1A Antikörper) activity for survival.
The pathogenicity of ZEB2 loss of heterozygosity in bovine is described.
characterization of differentiation dynamics reveals that Sip1 has a role in promoting the timely differentiation of retinal interneurons, assuring generation of the proper number of the diverse neuronal and glial cell subtypes that constitute the functional retina in mammals.
Zeb2 controls Schwann cell maturation by recruiting HDAC1 (zeige HDAC1 Antikörper)/2-NuRD complexes and inhibiting a Notch (zeige NOTCH1 Antikörper)-Hey2 (zeige HEY2 Antikörper) signaling axis
that Zeb2, although undetectable in adult Schwann cells, has a latent function throughout life
Zeb2 regulates commitment to both the cDC2 and pDC lineages through repression of Id2.
Control of differentiation of mouse enteric nervous system progenitor cells by EDN3 (zeige EDN3 Antikörper) requires regulation of Ednrb (zeige EDNRB Antikörper) expression by SOX10 (zeige SOX10 Antikörper) and ZEB2.
TFAP2A (zeige TFAP2A Antikörper) is a conserved component of the core network that regulates EMT (zeige ITK Antikörper), acting as a repressor of many genes, including ZEB2.
SIP1 plays an essential role in lipid metabolism during the liver regeneration process and might be a regulator of liver regeneration following liver injury.
Authors systematically generated de novo Zeb2 Deltaex7/+ mice by inducing the Zeb2 mutation in the germ cells
Data show that zebrafish sip1a and sip1b are essential for normal axial and neural patterning.
Knockdown of ChCh (zeige CHURC1 Antikörper) or Sip1a results in misshapen somites that are short and narrow.
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
zinc finger homeobox 1b
, zinc finger E-box binding homeobox 2
, zinc finger homeobox protein
, Smad-interacting protein 1
, smad interaction protein 1
, SMAD interacting protein 1
, zinc finger E-box-binding homeobox 2
, smad-interacting protein 1
, zinc finger homeobox protein 1b
, Smad-interacting protein-1a
, transcription factor SIP1a
, Smad-interacting protein-1b
, transcription factor SIP1b