anti-HAND1 (HAND1) Antikörper

Bezeichnung:
anti-Heart and Neural Crest Derivatives Expressed 1 Antikörper (HAND1)
Auf www.antikoerper-online.de finden Sie aktuell 86 Heart and Neural Crest Derivatives Expressed 1 (HAND1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HAND1 Proteine (13) und HAND1 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 110 HAND1 Produkte verfügbar.
Synonyme:
bHLHa27, eHAND, Ehand1, hand-1, Hand1, hand1-A, HXT, Th1, Thing1

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anti-Human HAND1 Antikörper:

anti-Rat (Rattus) HAND1 Antikörper:

anti-Mouse (Murine) HAND1 Antikörper:

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Am meisten referenzierte anti-HAND1 Antikörper

  1. Human Polyclonal HAND1 Primary Antibody für WB - ABIN658328 : Reamon-Buettner, Ciribilli, Traverso, Kuhls, Inga, Borlak: A functional genetic study identifies HAND1 mutations in septation defects of the human heart. in Human molecular genetics 2009 (PubMed)
    Zeige alle 4 Referenzen für 658328

  2. Human Monoclonal HAND1 Primary Antibody für ELISA, WB - ABIN969184 : Dai, Cserjesi: The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 2 Referenzen für 969184

  3. Human Monoclonal HAND1 Primary Antibody für ELISA, WB - ABIN4316554 : Lu, Du, Shan, Wang, Ma, Dong: Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture. in Biochemical and biophysical research communications 2016 (PubMed)

  4. Human Polyclonal HAND1 Primary Antibody für IHC, ELISA - ABIN1532673 : Knöfler, Meinhardt, Vasicek, Husslein, Egarter: Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart. in Gene 1999 (PubMed)

  5. Human Polyclonal HAND1 Primary Antibody für ICC, IF - ABIN4316555 : Zhang, Chen, Ye, Wang, Wang, Yuan, Lin, Wu, Zhang, Lin: Wnt signaling promotes hindgut fate commitment through regulating multi-lineage genes during hESC differentiation. in Cellular signalling 2016 (PubMed)

Weitere Antikörper gegen HAND1 Interaktionspartner

Human Heart and Neural Crest Derivatives Expressed 1 (HAND1) Interaktionspartner

  1. Strikingly, human pluripotent stem cell antibody array showed that Hand1 overexpression resulted in substantial decrease in pluripotency markers (Nanog (zeige NANOG Antikörper), Oct3/4 (zeige POU5F1 Antikörper), Otx2 (zeige OTX2 Antikörper), Flk1 (zeige KDR Antikörper)) suggesting that Hand1 expression may be essential to attenuate the EMT (zeige ITK Antikörper) and our findings underscore a novel role for Hand1 in medulloblastoma metastasis.

  2. association of HAND1 loss-of-function mutation with increased susceptibility to Tetralogy of Fallot

  3. These findings expand the phenotypic spectrum linked to HAND1 mutations, suggesting potential implications for the development of novelo prophylactic and therapeutic strategies for DORV.

  4. HAND1 loss-of-function mutation is associated with familial dilated cardiomyopathy.

  5. Combined expression of NKX2-5 (zeige NKX2-5 Antikörper), HAND1, and NOTCH1 (zeige NOTCH1 Antikörper) coordinately contribute to cardiac malformations in Hhypoplastic left heart syndrome.

  6. These data show that miR (zeige MLXIP Antikörper)-363 negatively regulates the expression of HAND1

  7. Nuclear translocation of Hand-1 acts as a molecular switch to regulate vascular radiosensitivity in medulloblastoma tumors.

  8. DNA methylation (zeige HELLS Antikörper) status of NKX2-5 (zeige NKX2-5 Antikörper), GATA4 (zeige GATA4 Antikörper) and HAND1 in patients with tetralogy of fallot

  9. Increased methylation levels of HAND1 is associated with highly active Helicobacter pylori-related gastritis.

  10. This is the first report of mutations in the HAND1 gene in Chinese patients with VSD and provides new insight into the etiology of VSD

Xenopus laevis Heart and Neural Crest Derivatives Expressed 1 (HAND1) Interaktionspartner

  1. a single nucleotide substitution in the hand1.S promoter was responsible for the reduced expression in the heart.

  2. increased vascular endothelial growth factor(170) levels disturb Hand-1 expression in the region required for normal heart morphogenesis

Mouse (Murine) Heart and Neural Crest Derivatives Expressed 1 (HAND1) Interaktionspartner

  1. Surviving Hand1;Hand2 (zeige HAND2 Antikörper) mutants display diminished cardiac function that is rescued by concurrent ablation of Hand-null cardiomyocytes. Collectively, we conclude that, within a mixed cardiomyocyte population, removal of defective myocardium and replacement with healthy endogenous cardiomyocytes may provide an effective strategy for cardiac repair.

  2. Within the pharyngeal arches, the distal-most of the proximo-distally oriented subdomains of cranial neural crest cells, the distal cap, is marked by expression of the transcription factor Hand1 and gives rise to the ectomesenchymal derivatives of the lower incisors.

  3. Data suggest the protection role of haploinsufficiency of heart and neural crest derivatives expressed transcript 1 protein (Hand1) after acute myocardial infarction (AMI (zeige CFD Antikörper)).

  4. Hand1 is involved in proper osteogenesis of the bone collar via its control of Ihh (zeige IHH Antikörper). Hand1 overexpression in the osteochondral progenitors caused defective prenatal diaphysis ossification. Hand1 inhibited Runx2 (zeige RUNX2 Antikörper) transactivation of the Ihh (zeige IHH Antikörper) proximal promoter.

  5. Re-expression of HAND1 in colon cancer cells induces terminal differentiation.

  6. Hand1 phosphoregulation in the distal arch neural crest has a critical role in craniofacial morphogenesis

  7. Suggest that prenatal alcohol exposure causes the over-expression of DHAND (zeige HAND2 Antikörper) and EHAND by increasing H3K14ac in the fetal heart.

  8. Hand1 is part of a novel regulatory pathway linking cardiac oxygen levels with oxygen consumption.

  9. that Hand1 homodimer plays a dominant role during development and its expression dosage is critical for survival, whereas Hand1 heterodimers can be either dispensable or play a regulatory role to modulate the activity of Hand1 homodimer in vivo.

  10. Data suggest that stress-induced MAPK8/9 and PRKAA1/2 regulate transcription factors Eomes/HAND1 and ID2, respectively. Together this network mediates induction of CSH1 by stress.

HAND1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Alternative names and synonyms associated with HAND1

  • heart and neural crest derivatives expressed 1 (HAND1) Antikörper
  • heart and neural crest derivatives expressed 1 (hand1) Antikörper
  • eHAND basic helix-loop-helix transcription factor (EHAND) Antikörper
  • heart and neural crest derivatives expressed 1 (Hand1) Antikörper
  • heart and neural crest derivatives expressed transcript 1 (Hand1) Antikörper
  • bHLHa27 Antikörper
  • eHAND Antikörper
  • Ehand1 Antikörper
  • hand-1 Antikörper
  • Hand1 Antikörper
  • hand1-A Antikörper
  • HXT Antikörper
  • Th1 Antikörper
  • Thing1 Antikörper

Bezeichner auf Proteinebene für HAND1

heart- and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed 1 , basic helix-loop-helix transcription factor HAND1 , eHAND basic helix-loop-helix transcription factor , Heart- and neural crest derivatives-expressed protein 1 , class A basic helix-loop-helix protein 27 , extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed transcript 1 , heart and neural crest derivatives-expressed protein 1 , eHAND , helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast , thing-1

GENE ID SPEZIES
489164 Canis lupus familiaris
541594 Sus scrofa
462209 Pan troglodytes
549497 Xenopus (Silurana) tropicalis
714450 Macaca mulatta
100009575 Oryctolagus cuniculus
9421 Homo sapiens
59112 Rattus norvegicus
517952 Bos taurus
395812 Gallus gallus
443353 Ovis aries
373663 Xenopus laevis
15110 Mus musculus
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