Coq7 Proteine (Coq7)

Bezeichnung:
Coenzyme Q Biosynthesis Protein 7 Proteine (Coq7)
Auf www.antikoerper-online.de finden Sie aktuell 9 Coenzyme Q Biosynthesis Protein 7 (Coq7) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Coq7 Antikörper (42) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 56 Coq7 Produkte verfügbar.
Synonyme:
CAT5, clk-1, CLK1
alle Proteine anzeigen Gen GeneID UniProt
Coq7 10229 Q99807
Ratte Coq7 Coq7 25249  
Coq7 12850 P97478

Weitere Synonyme anzeigen

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Am meisten referenzierte Coq7 Proteine

  1. Human Coq7 Protein expressed in Human Cells - ABIN2005107 : Ewbank, Barnes, Lakowski, Lussier, Bussey, Hekimi: Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. in Science (New York, N.Y.) 1997 (PubMed)
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Weitere Proteine zu Coq7 Interaktionspartnern

Human Coenzyme Q Biosynthesis Protein 7 (Coq7) Interaktionspartner

  1. Mitochondrial COQ9 (zeige COQ9 Proteine) is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

  2. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1 (zeige CDK11B Proteine).

  3. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1 (zeige SOD1 Proteine)) mRNA levels and activity

Mouse (Murine) Coenzyme Q Biosynthesis Protein 7 (Coq7) Interaktionspartner

  1. Mitochondrial COQ9 (zeige COQ9 Proteine) is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

  2. These findings indicate that MCLK1 (also known as Coq7) regulates both coenzyme Q synthesis and distribution within mitochondrial membranes.

  3. CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA.

  4. clk-1 deficiency induces apoptosis associated with mitochondrial dysfunction in mouse embryos.

  5. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1.

  6. Reduction in COQ7 levels gradually prevents the deterioration of mitochondrial function and associated increase of global oxidative stress that is normally observed in Sod2 (zeige SOD2 Proteine)(+/-) mutants.

Caenorhabditis elegans (C. elegans) Coenzyme Q Biosynthesis Protein 7 (Coq7) Interaktionspartner

  1. Nuclear CLK-1 mediates a retrograde signalling pathway that is conserved from Caenorhabditis elegans to humans and is responsive to mitochondrial reactive oxygen species, thus acting as a barometer of oxidative metabolism.

  2. no measurable intrinsic ETC defect exists in clk-1 mitochondria. The data indicate that DMQ(9) specifically inhibits electron transfer from complex I to ubiquinone.

  3. Prolonged life span of Clk mutants cannot be attributed to reduced metabolic rate or an increased activity of the major antioxidant enzymes catalase and SOD.

  4. Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1.

  5. Caenorhabditis elegans clk-1 mutants are sensitive to ubiquinone side-chain length

  6. in maternally resqued animals, the effect of clk-1 mutations on adult lifespan in uncoupled from their effects on development and reproduction

  7. differential fertility of clk-1 mutant nematodes fed Q isoforms may result from changes in Q localization, altered recognition by Q-binding proteins, and/or potential defects in mitochondrial function resulting from the mutant CLK-1 polypeptide itself.

  8. Suppressors of the missense mutation of clk-1 were identified; each mutant suppresses a different subset of phenotypes.

  9. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1.

Coq7 Protein Überblick

Protein Überblick

The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Coq7

  • coenzyme Q7 homolog, ubiquinone (yeast) (COQ7)
  • coenzyme Q7 homolog, ubiquinone (yeast) (Coq7)
  • demethyl-Q 7 (Coq7)
  • Protein CLK-1 (clk-1)
  • CAT5 Protein
  • clk-1 Protein
  • CLK1 Protein

Bezeichner auf Proteinebene für Coq7

COQ7 coenzyme Q, 7 homolog ubiquinone , coenzyme Q biosynthesis protein 7 homolog , placental protein KG-20 , timing protein clk-1 homolog , ubiquinone biosynthesis protein COQ7 homolog , Coenzyme q (ubiquinone) biosynthetic enzyme (DHPB methyltransferase) 7 , demethyl-Q 7

GENE ID SPEZIES
10229 Homo sapiens
25249 Rattus norvegicus
504771 Bos taurus
12850 Mus musculus
175729 Caenorhabditis elegans
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