CITED2 Proteine (CITED2)

Bezeichnung:
Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 Proteine (CITED2)
Auf www.antikoerper-online.de finden Sie aktuell 15 Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CITED2 Antikörper (60) und CITED2 Kits (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 96 CITED2 Produkte verfügbar.
Synonyme:
AI835299, ASD8, cite2, CITED2, ER154-like, MRG-1, Mrg1, Msg2, P35SRJ, VSD2, zgc:103418
alle Proteine anzeigen Gen GeneID UniProt
CITED2 10370 Q99967
CITED2 17684 O35740
Ratte CITED2 CITED2 114490  

Weitere Synonyme anzeigen

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Am meisten referenzierte CITED2 Proteine

  1. Human CITED2 Protein expressed in Escherichia coli (E. coli) - ABIN666771 : Bijl, Thompson, Ramirez-Solis, Krosl, Grier, Lawrence, Sauvageau: Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. in Blood 2006 (PubMed)
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Weitere Proteine zu CITED2 Interaktionspartnern

Human Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) Interaktionspartner

  1. The results suggest that CITED2 mutations in conserved regions lead to disease-causing biological and functional changes and may contribute to the occurrence of conotruncal heart defects in Chinese children.

  2. CITED2 gene mutation may play a significant role in the development of pediatric congenital heart disease.

  3. CITED2 supports gastric cancer cell colony formation and proliferation while inhibiting apoptosis making it a potential gene therapy target for gastric cancer.

  4. Through allosteric enhancement of HIF-1alpha (zeige HIF1A Proteine) release, CITED2 activates a highly responsive negative feedback circuit that rapidly and efficiently attenuates the hypoxic response, even at modest CITED2 concentrations.

  5. down-regulation of Cited2 was associated with high glucose-induced apoptosis in cardiomyocytes in vitro

  6. High Cited2 level in cumulus cells was associated with low embryo quality and pregnancy outcome in in vitro fertilization patients.

  7. the downregulation of CITED2 contributes to TGFbeta (zeige TGFB1 Proteine)-mediated senescence.

  8. CITED2 plays important roles in the progression and chemoresistance of breast carcinoma and that CITED2 status is a potent prognostic factor in breast cancer patients.

  9. Intrinsic protein disorder plays a prominent role in the function and interactions of the transcriptional co-activators CBP (zeige CREBBP Proteine) and p300 (zeige EP300 Proteine). (Review)

  10. FBXL5 (zeige FBXL5 Proteine)-mediated degradation of CITED2 leads to the activation of HIF-1 alpha (zeige HIF1A Proteine).

Mouse (Murine) Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) Interaktionspartner

  1. This study demonstrated that Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity in mice.

  2. Study showed a novel function of miR (zeige MLXIP Proteine)-200b and CITED2 in high glucose-induced unfolded protein response and ER stress, suggesting that miR (zeige MLXIP Proteine)-200b and CITED2 are critical for ER homeostasis and neural tube defect formation in the developing embryo.

  3. MicroRNAs in the Myocyte Enhancer Factor 2 (MEF2 (zeige MEF2C Proteine))-regulated Gtl2-Dio3 (zeige DIO3 Proteine) Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2.

  4. Cited2 is required for and enhances reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells.

  5. Cited2 is required for the maintenance of adult hematopoietic stem cell glycolytic metabolism likely through regulating Pdk2 (zeige PDK2 Proteine), Pdk4 (zeige PDK4 Proteine), lactate dehydrogenases B and D, and Akt (zeige AKT1 Proteine) activity.

  6. Cited2 in sinusoidal trophoblast giant cells and syncytiotrophoblasts is likely to have a non-cell autonomous role in patterning of the pericytes associated with the embryonic capillaries.

  7. a deletion of Cited2 in mESCs results in abnormal mitochondrial morphology and impaired glucose metabolism, which correlates with a defective cell fate decision.

  8. CITED2 is phosphorylated by MAPK1 (zeige MAPK1 Proteine) in vitro at T166, and that MAPK1 (zeige MAPK1 Proteine) activation enhances the coactivation function of CITED2 but not of CITED2-T166N.

  9. Cited2 controls ESC pluripotency and differentiation via direct regulation of Oct4 (zeige POU5F1 Proteine) gene expression.

  10. This study demonistrated that loss of hepatic CITED2 function suppresses gluconeogenesis in diabetic mice, suggesting it as a therapeutic target for hyperglycemia

CITED2 Protein Überblick

Protein Überblick

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with CITED2

  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (cited2)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2)
  • similar to Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal (CITED2)
  • Cbp/p300-interacting transactivator 2 (cite2)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (LOC100232815)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Cited2)
  • AI835299 Protein
  • ASD8 Protein
  • cite2 Protein
  • CITED2 Protein
  • ER154-like Protein
  • MRG-1 Protein
  • Mrg1 Protein
  • Msg2 Protein
  • P35SRJ Protein
  • VSD2 Protein
  • zgc:103418 Protein

Bezeichner auf Proteinebene für CITED2

TNeu124g09.1 , cbp/p300-interacting transactivator 2 , Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 , similar to Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal , Cbp/p300-interacting transactivator 2 , MSG-related protein 1 , MSG1-related gene 1 , melanocyte-specific gene 1-related gene 1 , melanocyte specific gene 2 , cited2/melanocyte specific gene-related gene 1 MRG1

GENE ID SPEZIES
407853 Xenopus (Silurana) tropicalis
450024 Danio rerio
463032 Pan troglodytes
707729 Macaca mulatta
100135454 Ovis aries
100196689 Salmo salar
100232815 Taeniopygia guttata
10370 Homo sapiens
484010 Canis lupus familiaris
521378 Bos taurus
17684 Mus musculus
114490 Rattus norvegicus
495124 Xenopus laevis
395399 Gallus gallus
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