S100A8 Proteine (S100A8)

Bezeichnung:
S100 Calcium Binding Protein A8 Proteine (S100A8)
Auf www.antikoerper-online.de finden Sie aktuell 43 S100 Calcium Binding Protein A8 (S100A8) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen S100A8 Antikörper (254) und S100A8 Kits (60) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 373 S100A8 Produkte verfügbar.
Synonyme:
60B8Ag, AI323541, B8Ag, Caga, CFAg, CGLA, CP-10, EWWD, L1Ag, MA387, MIF, Mrp8, NIF, p8, S100A8, WW
alle Proteine anzeigen Gen GeneID UniProt
S100A8 85320 Q96J66
S100A8 116547 P50115
S100A8 20201 P27005

Weitere Synonyme anzeigen

S100A8 Proteine (S100A8) nach Spezies

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Am meisten referenzierte S100A8 Proteine

  1. Human S100A8 Protein expressed in Wheat germ - ABIN1319072 : Maiseyeu, Badgeley, Kampfrath, Mihai, Deiuliis, Liu, Sun, Parthasarathy, Simon, Croce, Rajagopalan: In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. in Arteriosclerosis, thrombosis, and vascular biology 2012 (PubMed)
    Zeige alle 5 Referenzen für 1319072

  2. Mouse (Murine) S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN667469 : Kerkhoff, Klempt, Sorg: Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). in Biochimica et biophysica acta 1999 (PubMed)
    Zeige alle 2 Referenzen für 667469

Weitere Proteine zu S100A8 Interaktionspartnern

Human S100 Calcium Binding Protein A8 (S100A8) Interaktionspartner

  1. Data show that E3 ubiquitin ligase (zeige MUL1 Proteine) HRD1 (HRD1 (zeige SYVN1 Proteine)) decreased the protein level of S100A8 through ubiquitination.

  2. High S100A8 expression is associated with glioblastoma.

  3. This study implicates S100A8 and S100A9 (zeige S100A9 Proteine) as important mediators of tumor cell aggressiveness, and highlights the therapeutic potential of S100A8 and S100A9 (zeige S100A9 Proteine) for interference of metastasis.

  4. Data indicate a statistical correlation between fecal calprotectin (FC) and gastrointestinal graft-versus-host disease (GvHD).

  5. Perinatal alarmins S100A8 and S100A9 (zeige S100A9 Proteine) specifically altered MyD88 (zeige MYD88 Proteine)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (zeige TRIM69 Proteine)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.

  6. Expression of S100A8, S100A9 (zeige S100A9 Proteine) and S100A12 (zeige S100A12 Proteine) is modulated by eicosapentaenoic acid and docosahexaenoic acid during Inflammation in adipose tissue and mononuclear cells.

  7. High S100A8 expression is associated with lung metastasis in malignant melanoma.

  8. Data show that the standardized nerve growth factor (NGF) concentration was negatively correlated with continuous pain, neuropathic pain and total score, and the standardized S100 proteins S100A8/A9 concentration was positively correlated with present pain intensity and continuous pain.

  9. S100A8 and S100A9 (zeige S100A9 Proteine) proteins in concentrations secreted by CD34 (zeige CD34 Proteine)(-)/CD31 (zeige HBA1 Proteine)(+) circulating angiogenic cells (CACs) with impaired function reduce endothelial cell capillary-like network formation. These effects appear to be mediated by Toll-like receptor 4 (zeige TLR4 Proteine) and are absent with S100A8 and S100A9 (zeige S100A9 Proteine) in concentrations secreted by healthy CD34 (zeige CD34 Proteine)(-)/CD31 (zeige HBA1 Proteine)(+) CACs.

  10. The present study shows that the protein expression of ABCC10 (zeige ABCC10 Proteine) significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients

Cow (Bovine) S100 Calcium Binding Protein A8 (S100A8) Interaktionspartner

  1. Data suggest that up-regulation of S100A8 and S100A9 (zeige S100A9 Proteine) is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.

Pig (Porcine) S100 Calcium Binding Protein A8 (S100A8) Interaktionspartner

  1. Study verified porcine calprotectin (S100A8/A9) expression at the protein level in multiple Haemophilus parasuis infected tissues and explored their molecular characterization.

Mouse (Murine) S100 Calcium Binding Protein A8 (S100A8) Interaktionspartner

  1. Neutrophil-derived S100A8/A9 promotes thrombocytosis in diabetic mice

  2. Perinatal alarmins S100A8 and S100A9 (zeige S100A9 Proteine) specifically altered MyD88 (zeige MYD88 Proteine)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (zeige RNF138 Proteine)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.

  3. S100a8 upregulation triggers NF-kappaB (zeige NFKB1 Proteine) signal pathway through RAGE (zeige AGER Proteine) and TLR4 (zeige TLR4 Proteine), in response to laser-induced dermis wound healing.

  4. Although MRP-8/-14 expression is highly increased in experimental, these proteins do not contribute to the pathogenesis in the effector phase of epidermolysis bullosa acquisita and bullous pemphigoid (zeige DST Proteine).

  5. TLR4 (zeige TLR4 Proteine), TLR2 also contributed to Mrp8-induced inflammatory response and tolerance.

  6. S100A8 appears to play a crucial role in the activation of the TLR4 (zeige TLR4 Proteine)/MD-2 (zeige LY96 Proteine) pathway and the promotion of a tumor growth-enhancing immune microenvironment.

  7. Rps14 (zeige RPS14 Proteine) haploinsufficiency in del(5q) myelodysplastic syndrome is linked to activation of the innate immune system and induction of S100A8-S100A9 (zeige S100A9 Proteine) expression, leading to a p53 (zeige TP53 Proteine)-dependent erythroid differentiation defect.

  8. S100A8 is primarily produced from CXCR2 (zeige CXCR2 Proteine)-expressing CD11b (zeige ITGAM Proteine)(+)Gr-1 (zeige GSR Proteine)(high) cells, and it upregulates TNF-alpha (zeige TNF Proteine) production in CD11b (zeige ITGAM Proteine)(+)F4/80(+) cells through cellular cross-talk, which is an important mechanism in the development of Nonalcoholic fatty liver disease

  9. Alarmins S100A8/S100A9 (zeige S100A9 Proteine) aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.

  10. This study identified Mrp8/14 and TLR4 (zeige TLR4 Proteine) as important modulators of the leukocyte recruitment cascade during inflammation via integrin beta2.

S100A8 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Alternative names and synonyms associated with S100A8

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11 (ABCC11)
  • S100 calcium binding protein A8 (S100A8)
  • S100 calcium binding protein A8 (S100a8)
  • S100 calcium binding protein A8 (calgranulin A) (S100a8)
  • 60B8Ag Protein
  • AI323541 Protein
  • B8Ag Protein
  • Caga Protein
  • CFAg Protein
  • CGLA Protein
  • CP-10 Protein
  • EWWD Protein
  • L1Ag Protein
  • MA387 Protein
  • MIF Protein
  • Mrp8 Protein
  • NIF Protein
  • p8 Protein
  • S100A8 Protein
  • WW Protein

Bezeichner auf Proteinebene für S100A8

ATP-binding cassette protein C11 , ATP-binding cassette sub-family C member 11 , ATP-binding cassette transporter MRP8 , ATP-binding cassette transporter sub-family C member 11 , multi-resistance protein 8 , multidrug resistance-associated protein 8 , MRP-8 , S100 calcium-binding protein A8 (calgranulin A) , calgranulin A , calgranulin-A , calprotectin L1L subunit , cystic fibrosis antigen , leukocyte L1 complex light chain , migration inhibitory factor-related protein 8 , protein S100-A8 , urinary stone protein band A , S100 calcium binding protein A8 (calgranulin A) , p8 , S100 calcium binding protein A8 , BEE11 , P7 , S100 calcium-binding protein A8 , neutrophil cytosolic 7 kDa protein , calprotectin , chemotactic S100 protein , chemotactic cytokine CP-10 , pro-inflammatory S100 cytokine

GENE ID SPEZIES
85320 Homo sapiens
6279 Homo sapiens
116547 Rattus norvegicus
457319 Pan troglodytes
490461 Canis lupus familiaris
616818 Bos taurus
714740 Macaca mulatta
100127488 Sus scrofa
100294529 Equus caballus
20201 Mus musculus
100735514 Cavia porcellus
101104026 Ovis aries
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