anti-HYAL2 (HYAL2) Antikörper

Bezeichnung:
anti-Hyaluronidase-2 Antikörper (HYAL2)
Auf www.antikoerper-online.de finden Sie aktuell 96 Hyaluronidase-2 (HYAL2) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HYAL2 Kits (14) und HYAL2 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 124 HYAL2 Produkte verfügbar.
Synonyme:
AI256841, AU020858, AW555733, hyal2, hyal2a, hyal2b, luca-2, LUCA2, oHyal2, si:dkey-42i9.14, xhyal2
Alle Antikörper anzeigen Gen GeneID UniProt
HYAL2 8692 Q12891
HYAL2 15587 O35632
HYAL2 64468  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-HYAL2 (HYAL2) Antikörper

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anti-Human HYAL2 Antikörper:

anti-Mouse (Murine) HYAL2 Antikörper:

anti-Rat (Rattus) HYAL2 Antikörper:

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Am meisten referenzierte anti-HYAL2 Antikörper

  1. Human Polyclonal HYAL2 Primary Antibody für ELISA, WB - ABIN1327669 : Monzón, Manzanares, Schmid, Casalino-Matsuda, Forteza: Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells. in American journal of respiratory cell and molecular biology 2008 (PubMed)
    Zeige alle 3 Referenzen für 1327669

  2. Human Polyclonal HYAL2 Primary Antibody für EIA, FACS - ABIN952809 : Monzon, Fregien, Schmid, Falcon, Campos, Casalino-Matsuda, Forteza: Reactive oxygen species and hyaluronidase 2 regulate airway epithelial hyaluronan fragmentation. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 952809

  3. Human Polyclonal HYAL2 Primary Antibody für EIA, IHC (p) - ABIN952808 : de la Motte, Nigro, Vasanji, Rho, Kessler, Bandyopadhyay, Danese, Fiocchi, Stern: Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines. in The American journal of pathology 2009 (PubMed)
    Zeige alle 3 Referenzen für 952808

Weitere Antikörper gegen HYAL2 Interaktionspartner

Rabbit Hyaluronidase-2 (HYAL2) Interaktionspartner

Human Hyaluronidase-2 (HYAL2) Interaktionspartner

  1. Knocking down HYAL2 in HUVECs protected against HA degradation in the glycocalyx by inhibiting the expression and activity of HYAL2 and further blocked the dephosphorylation of eNOS (zeige NOS3 Antikörper)-Ser (zeige SIGLEC1 Antikörper)-633 and the decrease in NO production in response to LSS (zeige LSS Antikörper).

  2. HYAL2 mutations identified as a cause of syndromic orofacial clefting and cor triatriatum sinister in amish families.

  3. our data uncover a previously unsuspected mechanism of how hyaluronan and Hyal-2 control platelet generation.

  4. Data show that DNA methylation (zeige HELLS Antikörper) at CpG island of hyaluronoglucosaminidase 2 (HYLA2) could be used to identify stage II and III colon cancer patients who are most likely to benefit from 5-flourouracil chemotherapy with respect to progression-free survival.

  5. CD44 (zeige CD44 Antikörper) knock-down in bovine and human chondrocytes results in release of bound HYAL2.

  6. High expression of S100P (zeige S100P Antikörper) and HYAL2 is significantly associated with advanced disease and shorter survival of triple-negative breast cancer and S100P (zeige S100P Antikörper) and HYAL2 could be potential prognostic markers of TNBC.

  7. HYAL2 plays a redundant role in the catalysis of megadalton HA to its 20 kDa intermediate during fertilization.

  8. Lower platelet HYAL2 levels and activity are associated with inflammatory bowel disease.

  9. A strong association between decreased HYAL2 methylation in peripheral blood and BC.

  10. Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma.

Mouse (Murine) Hyaluronidase-2 (HYAL2) Interaktionspartner

  1. It was concluded that: HYAL1 (zeige HYAL1 Antikörper) and HYAL2 are both needed for tissue HA catabolism; 2) HYAL2 is required for high MW HA clearance in lymph nodes and plasma and for HA endocytosis by liver NPCs; and 3) the main role of HYAL1 (zeige HYAL1 Antikörper) is HA degradation within liver NPCs.

  2. Hyal2-/- mice present craniofacial abnormalities, including submucosal cleft palate and incompletely penetrant cor triatriatum sinister with hearing loss.

  3. our data uncover a previously unsuspected mechanism of how hyaluronan and Hyal-2 control platelet generation.

  4. Removal of Hyal2 activity resulted in increased levels of hyaluronan creating a risk for cor triatriatum sinister.

  5. hyaluronidase 2 deficiency induces chronic thrombotic microangiopathy with hemolytic anemia in mice.

  6. HYAL1 (zeige HYAL1 Antikörper) is necessary for the breakdown of intracellular HA in the cortex, whereas HYAL2 is essential for the degradation of extracellular HA in all kidney regions

  7. HYAL2 plays a redundant role in the catalysis of megadalton HA to its 20 kDa intermediate during fertilization.

  8. Murine hyaluronidase 2 deficiency results in extracellular hyaluronan accumulation and severe cardiopulmonary dysfunction

  9. Hyal-2 enhancement of tumor necrosis factor-alpha (zeige TNF Antikörper)-stimulated cytotoxicity in fibroblasts is blocked by Transforming growth factor-beta1.

  10. Hyaluronidase (zeige HAase Antikörper) induces ovarian granulosa cell apoptosis and is involved in follicular atresia.

Cow (Bovine) Hyaluronidase-2 (HYAL2) Interaktionspartner

  1. CD44 (zeige CD44 Antikörper) knock-down in bovine and human chondrocytes results in release of bound HYAL2.

  2. HYAL2 expression improves the blastocyst rate and embryo quality, an effect which requires CD44 (zeige CD44 Antikörper) activity and MAPK (zeige MAPK1 Antikörper) signaling.

  3. May degrade hyaluronan by analogy to human HYAL2, which is a weak acid-active hyaluronidase (zeige HAase Antikörper). Serves as an entry receptor for jaagsiekte sheep retrovirus in sheep and bovine as well as for enzootic nasal tumor virus in sheep.

HYAL2 Antigen-Profil

Beschreibung des Gens

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.

Alternative names and synonyms associated with HYAL2

  • hyaluronoglucosaminidase 2 (hyal2-b) Antikörper
  • hyaluronoglucosaminidase 2 (HYAL2) Antikörper
  • hyaluronoglucosaminidase 2 (hyal2) Antikörper
  • hyaluronoglucosaminidase 2 (hyal2-a) Antikörper
  • hyaluronoglucosaminidase 2 (Hyal2) Antikörper
  • AI256841 Antikörper
  • AU020858 Antikörper
  • AW555733 Antikörper
  • hyal2 Antikörper
  • hyal2a Antikörper
  • hyal2b Antikörper
  • luca-2 Antikörper
  • LUCA2 Antikörper
  • oHyal2 Antikörper
  • si:dkey-42i9.14 Antikörper
  • xhyal2 Antikörper

Bezeichner auf Proteinebene für HYAL2

hyaluronidase 2 b , hyaluronoglucosaminidase 2 , hyaluronidase-2 , hyaluronidase 2 , hyaluronidase 2 a , hyaluronidase-2-like , PH-20 homolog , PH20 homolog , hyal-2 , hyaluronoglucosaminidase-2 , lung carcinoma protein 2 , lysosomal hyaluronidase , GPI-anchored surface protein , JSRV envelope protein receptor

GENE ID SPEZIES
380470 Xenopus laevis
415908 Gallus gallus
460391 Pan troglodytes
484760 Canis lupus familiaris
559228 Danio rerio
702484 Macaca mulatta
100009375 Oryctolagus cuniculus
100144942 Xenopus (Silurana) tropicalis
100337508 Xenopus laevis
100407141 Callithrix jacchus
100453650 Pongo abelii
8692 Homo sapiens
15587 Mus musculus
64468 Rattus norvegicus
443154 Ovis aries
281838 Bos taurus
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