Heme Oxygenase (Decycling) 1 Proteine (HMOX1)

Bezeichnung:
Heme Oxygenase (Decycling) 1 Proteine (HMOX1)
Auf www.antikoerper-online.de finden Sie aktuell 44 Heme Oxygenase (Decycling) 1 (HMOX1) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Heme Oxygenase (Decycling) 1 Antikörper (360) und Heme Oxygenase (Decycling) 1 Kits (59) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 470 Heme Oxygenase (Decycling) 1 Produkte verfügbar.
Synonyme:
ARABIDOPSIS THALIANA HEME OXYGENASE 1, ATHO1, bK286B10, D8Wsu38e, F18A8.4, F18A8_4, GENOMES UNCOUPLED 2, GUN2, HEME OXYGENASE, HEME OXYGENASE 1, HEME OXYGENASE 6, Hemox, Heox, HEOXG, Hmox, Hmox1, HMOX1D, Ho-1, Ho1, hsp32, HY1, HY6, MGC132176, PLASTID HEME OXYGENASE, REVERSAL OF THE DET PHENOTYPE 4, wu:fc27c04, zgc:65984
alle Proteine anzeigen Gen GeneID UniProt
HMOX1 3162 P09601
HMOX1 15368 P14901
HMOX1 24451 P06762

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Am meisten referenzierte Heme Oxygenase (Decycling) 1 Proteine

  1. Rat (Rattus) HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN1686745 : Brydun, Watari, Yamamoto, Okuhara, Teragawa, Kono, Chayama, Oshima, Ozono: Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis. in Hypertension research : official journal of the Japanese Society of Hypertension 2007 (PubMed)
    Zeige alle 5 Referenzen für 1686745

  2. Human HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN666727 : Soares, Brouard, Smith, Bach: Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs. in Immunological reviews 2002 (PubMed)
    Zeige alle 2 Referenzen für 666727

Weitere Proteine zu Heme Oxygenase (Decycling) 1 Interaktionspartnern

Soybean (Glycine max) Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. study evaluated the time-course of HO-1 and catalase (zeige CAT Proteine) gene expressions in nodules and roots of soybean plants subjected to cadmium treatment

Xenopus laevis Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. Data suggest expression of hsp32 is up-regulated in kidney epithelial cells upon in vitro exposure to heavy metal water pollutants (Cd, As) or proteasomal inhibitors (MG132, withaferin A, celastrol); heat shock may be synergistic factor.

Zebrafish Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. this study provides a better understanding of the role of the HO-1/Carbon monoxide system in controlling heart function in lower vertebrates.

  2. The induced expression of HO-1 by fenofibrate appeared to be essential for mediating the protective effects of fenofibrate, as the inhibition of HO-1 activity significantly diminished the protective effects of fenofibrate against the GM-mediated death of sensory hair cells in cochlea

  3. Suggest that Gata-1 (zeige GATA1 Proteine) and Nrf2a (zeige NFE2L2 Proteine) play differential roles in regulating the heme degradation enzymes hmox1a/bvra (zeige BLVRA Proteine)/bvrb (zeige BLVRB Proteine) during an early developmental period of heightened cellular stress.

  4. Bach1 (zeige BACH1 Proteine) regulates the liver specificity and transience of the Nrf2a (zeige NFE2L2 Proteine)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (zeige BACH1 Proteine) inhibition based on its level in each tissue.

Arabidopsis thaliana Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. Data indicate that Heme oxygenase 1 (HY1) functioned negatively and acted upstream of ABSCISIC ACID-INSENSITIVE4 (ABI4) in drought signaling.

  2. HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis.

  3. Data indicate that AtHO1 (HY1; heme oxygenase-1)-overexpressing plants generated more NO, whereas knock-down of AtHO1 expression reduced the level of nitric oxide (NO) in plants.

  4. HY1 mutant exhibited progressive salt hypersensitivity.

  5. Disrupting the binding of the AtHBP5 to haem oxygenase 1 (HY1) leads to oxidative stress.

  6. Mutation of HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence.

  7. HY1 and HY5 additively regulate the expression of light regulated genes and accumulation of chlorophyll and anthocyanin during early seedling development.

  8. HY1 (Heme oxygenase 1) plays an important role in salt acclimation.

  9. all members of the HO1 subfamily (HY1, HO3 and HO4) are active monomeric HOs and can convert haem to BV IXalpha using spinach Fd (ferredoxin) as an electron donor

Synechocystis PCC 6803 Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. HO2 (zeige HMOX2 Proteine) has an activity high enough to substitute for HO1 under aerobic conditions.

Human Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 (zeige PCBP2 Proteine) competes with CPR (zeige POR Proteine) for binding HO1; PCBP2 (zeige PCBP2 Proteine) K homology 3 domain is important for HO1/PCBP2 (zeige PCBP2 Proteine) interaction; heme prompts HO1/CPR (zeige POR Proteine) multimer and decreases HO1/PCBP2 (zeige PCBP2 Proteine) multimer. [PCBP2 (zeige PCBP2 Proteine) = poly(rC) binding protein 2 (zeige PCBP2 Proteine); CPR (zeige POR Proteine) = cytochrome P450 reductase (zeige POR Proteine); HO1 = heme oxidase 1]

  2. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4 (zeige NOX4 Proteine), with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species.These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2 (zeige GABPA Proteine)-dependent HO-1 expression

  3. We identified miR (zeige MLXIP Proteine)-1254 as a negative regulator inhibiting HO-1 translation by directly targeting HO-1 3'UTR via its seed region, and suppressing HO-1 transcription via non-seed region-dependent inhibition of transcriptional factor AP-2 alpha (TFAP2A (zeige TFAP2A Proteine)), a transcriptional activator of HO-1.

  4. cells with elevated HO-1 produced less reactive oxygen species, resulting in nuclear localization of HDAC4 (zeige HDAC4 Proteine) and miR (zeige MLXIP Proteine)-206 repression.

  5. Data suggest that cigarette smoke increases HO-1 (heme oxygenase-1) levels in bronchial epithelial cells via activation of NRF2 (NFE2-related factor 2 (zeige NFE2L2 Proteine)); exogenous neutrophil elastase (zeige ELANE Proteine) suppresses increase in HO-1 via proteolysis of sirtuin 1 (zeige SIRT1 Proteine).

  6. Polymorphisms within the promoter of HO-1 are prognostic factors for recurrence and survival in squamous cell carcinoma and adenocarcinoma of the esophagus.

  7. the results of this study suggest that extratumoral HO-1+ macrophages may have an important role in prostate cancer.

  8. Data suggest that expression of HMOX1 can be induced in hepatocytes by dietary factors that down-regulate oxidative stress; here, casein glycomacropeptide hydrolysates protect HepG2 cells from hydrogen peroxide-induced oxidative stress via induction of HMOX1 expression.

  9. In the NMA-conditioning setting transplantation of HO-1low donor cells into HO-1low recipients correlated significantly with decreased relapse related mortality (RRM) and longer progression free survival (PFS) (p = 0.03 and p = 0.008, respectively). Overall, our findings suggest that HO-1 may play a role for the induction of GVT effect after allogeneic HCT.

  10. peripheral blood monocytes (PBMCs) from elderly patients with Pulmonary infections with nontuberculous mycobacteria also demonstrated attenuated HO-1 responses after M. avium stimulation.

Pig (Porcine) Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. findings collectively suggest that miR (zeige MYLIP Proteine)-506 acts as a tumor suppressor via regulation of ROCK1 (zeige ROCK1 Proteine) expression and may thus be a promising therapeutic target for HCC (zeige FAM126A Proteine)

  2. Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.

  3. Down-regulation of HO-1 is associated with pulmonary arterial hypertension and right ventricular failure.

  4. The study revealed the involvement of HO-1 in classical swine fever virus proliferation.

  5. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  6. Glutamate (zeige GRIN2C Proteine) regulates Ca2 (zeige CA2 Proteine)+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms.

  7. obalt protoporphyrin prevents postictal cerebral vascular dysfunction by upregulating HO-1.

  8. Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF (zeige VEGFA Proteine), a specific endothelial cell growth factor (zeige FGF1 Proteine).

  9. Interaction of soluble factors in plasma possibly generated during PICSO are not responsible for upregulation of HO-1 and VEGF mRNA.

Cow (Bovine) Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. the data were consistent with HO-1 acting as an anti-viral factor and these findings suggested that induction of HO-1 may be a useful prevention and treatment strategy against BVDV infection.

  2. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 (zeige NFE2L2 Proteine) expression early in the course of infection, which results in increased expression of HO-1 within these cells.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: regulation of HO-1 gene expression in aortic endothelial cells by advanced glycation end products

  4. Sickle blood increases endothelial heme oxygenase activity.

  5. data provide evidence for the involvement of the thioredoxin/thioredoxin (zeige TXN Proteine) receptor system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge

  6. Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD/SOD3 (zeige SOD3 Proteine).

Mouse (Murine) Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. This is the first study to dissect the mechanism by which the antiadipogenic and anti-inflammatory lipid, Epoxyeicosatrienoic acid, induces the PGC-1alpha signaling cascade and reprograms the adipocyte phenotype by regulating mitochondrial function and HO-1 expression.

  2. The findings suggest that HO-1 by modulating TLR9 (zeige TLR9 Proteine) expression in PMCs promotes pleural innate immunity in MRSA (zeige MSR1 Proteine) empyema.

  3. HO-1 regulates not only cytokine/chemokine (zeige CCL1 Proteine) production in pregnant uteri but also myeloid cell receptor numbers.

  4. Administration of EET alters Wnt1 (zeige WNT1 Proteine), NOV (zeige NOV Proteine), and HO-1 signaling to prevent obesity-induced cardiomyopathy in obese mice.

  5. Studied the immunosuppressive role of HO-1 in sepsis with a focus on its effects on helper T-cell (Th) differentiation and regulatory T cells; found overexpressed HO-1 contributes to sepsis-induced immunosuppression by inducing a Th1 (zeige HAND1 Proteine) to Th2 cytokine shift and enhancing Treg function.

  6. Data indicate that chlorogenic acid (CGA (zeige CGA Proteine)) protected osteoblast MC3T3-E1 cells against oxidative damage via PI3K/Akt (zeige AKT1 Proteine)-mediated activation of Nrf2 (zeige NFE2L2 Proteine)/HO-1 pathway, which may be an effective drug in treatment of osteoporosis.

  7. our data suggest that the B. pseudomallei-mediated induction of HO-1 and the release of its metabolite carbon dixode impair bacterial clearance in macrophages and during murine melioidosis.

  8. HO-1 activation mediates early brain damage after ICH (zeige ACE Proteine) (intracerebral hemorrhage) but promotes neurologic function recovery in the later stage of ICH (zeige ACE Proteine)

  9. Heme Oxygenase 1 is associated with lung protection in malaria-associated acute lung injury/acute respiratory distress syndrome

  10. Irisin (zeige FNDC5 Proteine) improved endothelial function by modulating HO-1/ adiponectin (zeige ADIPOQ Proteine) axis in perivascular adipose tissue (PVAT) in HFD-induced obese mice. These findings suggest that regulating PVAT function may be a potential mechanism by which irisin (zeige FNDC5 Proteine) improves endothelial function in obesity.

Rabbit Heme Oxygenase (Decycling) 1 (HMOX1) Interaktionspartner

  1. Kidneys from circulation-restricted fetuses showed reduced heme oxygenase-1 mRNA.

  2. Ligustrazine injection possesses notable protective effects on ischemia/reperfusion injury in rabbits by increasing the expression of HO-1 in lung.

  3. Results add new evidence for the importance of HO-1 in the genesis and development of atherosclerosis and provide several possible mechanisms underlying the anti-atherosclerosis effects of HO-1

  4. the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism

  5. Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 (zeige HSP70 Proteine) expression and increasing CO production.

  6. These results suggest that HO-1 is important in limiting in-stent stenosis and can be regarded as a new therapeutic target.

  7. Statins showed anti-atherosclerotic effects mediated by HO-1/eNOS (zeige NOS3 Proteine), restoring the [NO]/[ONOO(-)] imbalance and reducing lipid peroxidation.

  8. HO-1/CO system was activated and may be one of the protective signal pathway during pulmonary ischemia-reperfusion injury in rabbits.

  9. HO-1 contributes to vascular repair by increasing circulating endothelial progenitor cells (EPCs) derived from the bone marrow.

Heme Oxygenase (Decycling) 1 (HMOX1) Protein Überblick

Protein Überblick

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

Alternative names and synonyms associated with Heme Oxygenase (Decycling) 1 (HMOX1)

  • heme oxygenase (decycling) 1 (HMOX1)
  • heme oxygenase 1 (HO1)
  • heme oxygenase (decycling) 1 (hmox1)
  • heme oxygenase 1 (TED4)
  • heme oxygenase (ho1)
  • heme oxygenase (CPE0214)
  • heme oxygenase 1 (ho1)
  • Heme oxygenase (ho1)
  • heme oxygenase 1 (AM1_C0205)
  • heme oxygenase 1 (CC1G_11686)
  • heme oxygenase 1 (CpipJ_CPIJ007246)
  • Heme oxygenase (Cyan7425_2962)
  • heme oxygenase (decycling) 1 (Hmox1)
  • ARABIDOPSIS THALIANA HEME OXYGENASE 1 Protein
  • ATHO1 Protein
  • bK286B10 Protein
  • D8Wsu38e Protein
  • F18A8.4 Protein
  • F18A8_4 Protein
  • GENOMES UNCOUPLED 2 Protein
  • GUN2 Protein
  • HEME OXYGENASE Protein
  • HEME OXYGENASE 1 Protein
  • HEME OXYGENASE 6 Protein
  • Hemox Protein
  • Heox Protein
  • HEOXG Protein
  • Hmox Protein
  • Hmox1 Protein
  • HMOX1D Protein
  • Ho-1 Protein
  • Ho1 Protein
  • hsp32 Protein
  • HY1 Protein
  • HY6 Protein
  • MGC132176 Protein
  • PLASTID HEME OXYGENASE Protein
  • REVERSAL OF THE DET PHENOTYPE 4 Protein
  • wu:fc27c04 Protein
  • zgc:65984 Protein

Bezeichner auf Proteinebene für HMOX1

heme oxygenase (decycling) 1 , heme oxygenase 1 , fc27c04 , heme oxygenase , Heme oxygenase , heat shock protein, 32-kD , HO-1 , heat shock protein 32 , heme oxygenase (decyclizing) 1 , P32 protein , hemoxygenase , heme oxygenase-1

GENE ID SPEZIES
470195 Pan troglodytes
547612 Glycine max
719266 Macaca mulatta
734976 Xenopus laevis
791518 Danio rerio
817208 Arabidopsis thaliana
953483 Synechocystis sp. PCC 6803
988459 Clostridium perfringens str. 13
1012610 Thermosynechococcus elongatus BP-1
1463132 Prochlorococcus marinus subsp. marinus str. CCMP1375
1726356 Prochlorococcus marinus subsp. pastoris str. CCMP1986
1732486 Synechococcus sp. WH 8102
4718538 Prochlorococcus marinus str. AS9601
4719905 Prochlorococcus marinus str. MIT 9515
4778405 Prochlorococcus marinus str. MIT 9303
4779884 Prochlorococcus marinus str. NATL1A
4911675 Prochlorococcus marinus str. MIT 9301
5157291 Synechococcus sp. RCC307
5615689 Prochlorococcus marinus str. MIT 9215
5686060 Acaryochloris marina MBIC11017
5730157 Prochlorococcus marinus str. MIT 9211
5862292 Microcystis aeruginosa NIES-843
6012319 Coprinopsis cinerea okayama7130
6039118 Culex quinquefasciatus
7288894 Cyanothece sp. PCC 7425
3162 Homo sapiens
445512 Sus scrofa
513221 Bos taurus
15368 Mus musculus
24451 Rattus norvegicus
442987 Canis lupus familiaris
100715748 Cavia porcellus
396287 Gallus gallus
100173339 Pongo abelii
100008919 Oryctolagus cuniculus
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