anti-Kaninchen ATP6V1C1 Antikörper für Western Blotting

Recommended ATP6V1C1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) Antikörper
  • ATP6C
  • ATP6D
  • VATC
  • Vma5
  • vatC
  • 1700025B18Rik
  • U13839
  • ATPase
  • atp6v1c1
  • si:zc215i13.2
  • wu:fd12h05
  • ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • ATPase H+ transporting V1 subunit C1
  • ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog
  • ATPase, H+ transporting, lysosomal V1 subunit C1
  • ATPase, H+ transporting, lysosomal, V1 subunit C1a
  • atp6v1c1
  • ATP6V1C1
  • atp6v1c1.L
  • Atp6v1c1
  • atp6v1c1a
Epitop
N-Term
3
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
25
13
9
1
1
1
1
1
1
1
1
Wirt
Kaninchen
28
1
Klonalität
Polyklonal
Konjugat
Dieser ATP6V1C1 Antikörper ist unkonjugiert
3
3
3
Applikation
Western Blotting (WB)
28
19
7
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2787751
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN464139 WB Rabbit IgG AA 61-110 Anmelden zum Anzeigen Polyclonal

General

Antigen ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) Antikörper
Epitop N-Term
(3), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
(25), (13), (9), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(28), (1)
Klonalität
Polyklonal
Konjugat Dieser ATP6V1C1 Antikörper ist unkonjugiert
(3), (3), (3)
Applikation Western Blotting (WB)
(28), (19), (7), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ATP6V1C1 Antikörper

Target Details ATP6V1C1 Anwendungsinformationen Handhabung Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973634.
Sequenz ldafvegvvk kvaqymadvl edskdkvqen llangvdlvt yitrfqwdma
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
Produktmerkmale This is a rabbit polyclonal antibody against ATP6V1C1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1C1

Target Details ATP6V1C1

Produktdetails anti-ATP6V1C1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751) Bilder zurück nach oben
Antigen
Andere Bezeichnung ATP6V1C1 (ATP6V1C1 Antibody Abstract)
Hintergrund ATP6V1C1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6C, ATP6D, FLJ20057, VATC, Vma5
Protein Interaction Partner: ATP6V1C1, IVNS1ABP, ATG7, DNM1L, TSN, STAT1, SNX2, SNX1, SHMT2, SHMT1, SARS, RDX, PAWR, NASP, IDE, GTF2A1, GSPT1, CTTN, PSMG3, ANP32E, TBC1D15, SNX6, VPS35, VPS29, LUC7L2, VTA1, ARFIP1, GSPT2, UBC, UBAC2, TXNDC17, MRPS35, CISD1, VASP, TYMS, SSR1, SRSF5, A
Protein Size: 382
Molekulargewicht 42 kDa
Gen-ID 528
NCBI Accession NM_001695, NP_001686
UniProt P21283
Forschungsgebiet Signaling, Metabolism
Pathways Transition Metal Ion Homeostasis, Proton Transport

Anwendungsinformationen

Produktdetails anti-ATP6V1C1 Antikörper Target Details ATP6V1C1 Handhabung Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 382 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ATP6V1C1 Antikörper Target Details ATP6V1C1 Anwendungsinformationen Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751)

Produktdetails anti-ATP6V1C1 Antikörper Target Details ATP6V1C1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Meo-Evoli, Almacellas, Massucci, Gentilella, Ambrosio, Kozma, Thomas, Tauler: "V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy." in: Oncotarget, Vol. 6, Issue 29, pp. 28057-70, 2015

Allgemeine Veröffentlichungen

Hurtado-Lorenzo, Skinner, El Annan, Futai, Sun-Wada, Bourgoin, Casanova, Wildeman, Bechoua, Ausiello, Brown, Marshansky: "V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway." in: Nature cell biology, Vol. 8, Issue 2, pp. 124-36, 2006

Bilder

Produktdetails anti-ATP6V1C1 Antikörper Target Details ATP6V1C1 Anwendungsinformationen Handhabung Referenzen für anti-ATP6V1C1 Antikörper (ABIN2787751) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (N-Term) antibody (ABIN2787751) WB Suggested Anti-ATP6V1C1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posi...