anti-Rind (Kuh) TLR5 Antikörper für Western Blotting

Recommended TLR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 5 (TLR5) Antikörper
  • TLR-5
  • sleb1
  • til3
  • tlr-5
  • SLEB1
  • TIL3
  • toll like receptor 5
  • toll like receptor 5 L homeolog
  • toll-like receptor 5
  • TLR5
  • tlr5.L
  • tlr-5
  • Tlr5
Epitop
N-Term
40
22
15
11
11
11
10
7
6
6
5
5
5
5
5
4
3
3
2
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Ziege, Human, Schwein, Ratte (Rattus), Schaf
240
146
45
45
4
2
1
1
Wirt
Kaninchen
157
97
4
Klonalität
Polyklonal
Konjugat
Dieser TLR5 Antikörper ist unkonjugiert
21
14
11
8
7
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Western Blotting (WB)
198
89
78
74
65
19
17
13
9
7
4
4
3
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2777429
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN467702 WB Rabbit AA 71-120 Anmelden zum Anzeigen Polyclonal

General

Antigen Toll-Like Receptor 5 (TLR5) Antikörper
Epitop N-Term
(40), (22), (15), (11), (11), (11), (10), (7), (6), (6), (5), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Ziege, Human, Schwein, Ratte (Rattus), Schaf
(240), (146), (45), (45), (4), (2), (1), (1)
Wirt Kaninchen
(157), (97), (4)
Klonalität
Polyklonal
Konjugat Dieser TLR5 Antikörper ist unkonjugiert
(21), (14), (11), (8), (7), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(198), (89), (78), (74), (65), (19), (17), (13), (9), (7), (4), (4), (3), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR5 Antikörper

Target Details TLR5 Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN2777429) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985139.
Sequenz QLQLLELGSQ YTPLTIDKEA FRNLPNLRIL DLGSSKIYFL HPDAFQGLFH
Homologie Cow: 79%, Goat: 79%, Human: 100%, Pig: 83%, Rat: 79%, Sheep: 79%
Produktmerkmale This is a rabbit polyclonal antibody against TLR5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TLR5

Target Details TLR5

Produktdetails anti-TLR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN2777429) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR5 (TLR5 Antibody Abstract)
Hintergrund TLR5 participates in the innate immune response to microbial agents. It mediates detection of bacterial flagellins. TLR5 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ10052, MGC126430, MGC126431, SLEB1, TIL3
Protein Interaction Partner: RNF216, SIGIRR, TLR4, MYD88, TLR1,
Protein Size: 858
Molekulargewicht 98 kDa
Gen-ID 7100
NCBI Accession NM_003268, NP_003259
UniProt O60602
Forschungsgebiet Immunology, Innate Immunity, Signaling, Inflammation
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Handhabung Referenzen für anti-TLR5 Antikörper (ABIN2777429) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 858 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Referenzen für anti-TLR5 Antikörper (ABIN2777429) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TLR5 Antikörper (ABIN2777429)

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Hume, Fowler, Doecke, Simms, Huang, Palmieri, Griffiths, Florin, Annese, Radford-Smith: "Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population." in: Inflammatory bowel diseases, Vol. 14, Issue 5, pp. 585-90, 2008

Bilder

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN2777429) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 5 (TLR5) (N-Term) antibody (ABIN2777429) WB Suggested Anti-TLR5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive...