TLR4 (TLR4) ELISA Kits

Auf www.antikoerper-online.de finden Sie aktuell 58 Toll-Like Receptor 4 (TLR4) ELISA Kits von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TLR4 Antikörper (613) und TLR4 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 707 TLR4 Produkte verfügbar.
Synonyme:
ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLL
list all ELISA KIts Gen GeneID UniProt
TLR4 7099 O00206
TLR4 21898 Q9QUK6
TLR4 29260 Q9QX05

TLR4 (TLR4) ELISA Kits nach Reaktivitäten

Weitere ELISA Kits für TLR4 Interaktionspartner

Human Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. Type I IFN is detrimental to the host, and dysregulation of iron homeostasis genes may explain lower bacteria survival in cGAS(-/-) and TLR4(-/-) cells.

  2. Here the authors show that MAL (zeige MAL ELISA Kits) TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 TIR domains and induce formation of MyD88 (zeige MYD88 ELISA Kits) assemblies.

  3. Experiments demonstrate for the first time that palmitic acid activation of TLR4 occurs in response to direct molecular interactions between palmitic acid and MD-2 (zeige LY96 ELISA Kits); suggest a likely molecular mechanism for palmitic acid induction of pro-inflammatory immune responses in human dendritic cells expressing TLR4.

  4. In LPS-stimulated HEK293 cells with low CD14 and high (zeige IRF6 ELISA Kits) TLR4, no accumulation of PI(4,5)P2 occurred. With an increasing amount of CD14 and decrease of TLR4, 2 peaks of PI(4,5)P2 appeared, approaching those found in LPS-stimulated cells expressing CD14 alone. This suggests that LPS-induced accumulation of PI(4,5)P2 that maximizes TLR4 signaling is controlled by CD14, whereas TLR4 can fine tune this via PI(4,5)P2 turnover.

  5. TLR4 coding SNPs Asp299Gly and Thr399Ile might be used as genetic susceptibility alleles for POAG

  6. Estradiol alters the immune-responsiveness of cultured HECECs to TLR2 (zeige TLR2 ELISA Kits) and TLR4 ligands in a complex fashion that appears to vary with bacterial ligand, TLR subtype, and duration of exposure

  7. Ligand-driven triggering of TLR-3 (zeige TLR3 ELISA Kits), -4, NOD2 (zeige NOD2 ELISA Kits), and DC-SIGN (zeige CD209 ELISA Kits), despite reducing viral replication, markedly increased the capacity of infected dendritic cells to stimulate HIV-specific cytotoxic T-cells.

  8. The study demonstrated that HIV infection sensitizes Kupffer cells to the proinflammatory effects of lipopolysaccharides in a TLR4-dependent manner.

  9. The lipid flippases, ATP8B1 (zeige ATP8B1 ELISA Kits) and ATP11A (zeige ATP11A ELISA Kits) are novel elements of the innate immune response that are essential to attenuate the inflammatory response, possibly by mediating endotoxin-induced internalization of TLR4.

  10. these findings identify new compounds for antagonizing TLR2 (zeige TLR2 ELISA Kits) and TLR4 activation and define structural properties of POPG analogs for discriminating between two TLR systems.

Mouse (Murine) Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. Stimulation of the TLR4-TRIF (zeige RNF138 ELISA Kits) pathway can protect against the development of allergic airway disease and that a TRIF (zeige RNF138 ELISA Kits)-dependent adjuvant effect on CD4 (zeige CD4 ELISA Kits)(+) ICOS (zeige ICOS ELISA Kits)(+) T-cell responses may be a contributing mechanism.

  2. HMGB1 (zeige HMGB1 ELISA Kits) activates the NF-kappaB (zeige NFKB1 ELISA Kits) and JNK (zeige MAPK8 ELISA Kits)/p38 (zeige CRK ELISA Kits) pathways through TLR4/MyD88 (zeige MYD88 ELISA Kits)-dependent signaling and induces an inflammatory response in lungs exposed to cigarette smoke.

  3. Findings reveal that TLR4 mutant significantly abated the intestinal IR injury and ALI at least in part by alleviating the inflammatory response and oxidative stress.

  4. These findings indicate that TLR2 (zeige TLR2 ELISA Kits) and TLR4 are required to control Brucella microti infection in mice and that this effect could be related to its participation in the maturation of dendritic cells and the generation of specific CD8 (zeige CD8A ELISA Kits)(+) Tc cells.

  5. Monophosphoryl lipid A stimulation of a TLR4-TRIF (zeige RNF138 ELISA Kits)-PI3K-Akt (zeige AKT1 ELISA Kits) pathway prevents lipopolysaccharide-induced ERK (zeige EPHB2 ELISA Kits) activation in the medullar thick ascending limb.

  6. Results show that TLR4 plays a critical role in the effects of dietary fat composition on the development of hepatic steatosis, inflammation, and injury consistent with nonalcoholic steatohepatitis.

  7. FasL (zeige FASL ELISA Kits) expression in splenic CD5 (zeige CD5 ELISA Kits)(+)CD1d (zeige CD1D ELISA Kits)(hi) B cells was decreased compared to the control group after TLR4 ligation.

  8. Stimulation of murine peritoneal macrophages with LPS induces biphasic accumulation of PI(4,5)P2 with peaks at 10 and 60-90 min that were still seen after silencing of TLR4 expression, questioning the involvement of TLR4 in this process.

  9. Data suggest that the transmembrane domains of Tlr4 and Tlr6 (zeige TLR6 ELISA Kits) have essential roles in Tlr4/Tlr6 (zeige TLR6 ELISA Kits)/Cd36 (zeige CD36 ELISA Kits) receptor multimerization and activation; disruption of receptor multimerization (here, using a recombinant peptide fragment from Tlr4 transmembrane domain) reduces secretion of proinflammatory mediators from microglia and ultimately rescues neurons from death.

  10. This study demonstrated that TLR4 deficiency contributes to regulating microglia to switch to the M2 phenotype, which ameliorates neurological impairment after traumatic brain injury in mice.

Cow (Bovine) Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. TLR4 polymorphisms are associated with lower reproductive Performance.

  2. As a pilot study, the present results revealed that identified SNPs in IL8 (zeige IL8 ELISA Kits) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.

  3. Transcription levels of TLR2 (zeige TLR2 ELISA Kits), TLR4, and CD14 (zeige CD14 ELISA Kits) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.

  4. Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.

  5. TLR2 (zeige TLR2 ELISA Kits) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  6. TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins

  7. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (zeige TLR2 ELISA Kits) and TLR4 with the formation of NETs and change in surface architecture.

  8. Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (zeige CCL2 ELISA Kits)) genes.

  9. Studied bovine TLR4 gene in mastitis resistance by association as well as expression profiling analysis in crossbred cattle.

  10. Findings indicate that intervertebral disc (IVD (zeige IVD ELISA Kits)) cells constitutively express TLR4.

Rabbit Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. TLR2 (zeige TLR2 ELISA Kits), 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.

  2. The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (zeige NFKB1 ELISA Kits) (p65 (zeige SYT1 ELISA Kits)) were respectively detected.

  3. Lipopolysaccharide upregulates the expression of rabbit TLR2 (zeige TLR2 ELISA Kits) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.

  4. Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (zeige NFKB1 ELISA Kits) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (zeige ICAM1 ELISA Kits).

  5. TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage

  6. The elevated expression of TLR4 was detected after SAH (zeige ACSM3 ELISA Kits) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (zeige ACSM3 ELISA Kits).

Pig (Porcine) Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (zeige MAMLD1 ELISA Kits) in Meishan weaned piglets.

  2. Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (zeige IRF6 ELISA Kits) challenge.

  3. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.

  4. Data suggest TLR2 (zeige TLR2 ELISA Kits), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (zeige TLR2 ELISA Kits)/TLR4.

  5. TLR2 (zeige TLR2 ELISA Kits) is required for the suppression of TLR4 signaling activation.

  6. The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.

  7. The role of TLR2 (zeige TLR2 ELISA Kits), TLR4 and RP105 (zeige CD180 ELISA Kits)/MD1 (zeige LY86 ELISA Kits) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (zeige CLPTM1 ELISA Kits), is reported.

  8. Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.

  9. Fish Oil attenuates the activation of the HPA (zeige HPSE ELISA Kits) axis induced by LPS (zeige IRF6 ELISA Kits) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.

  10. Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.

Horse (Equine) Toll-Like Receptor 4 (TLR4) Interaktionspartner

  1. The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.

  2. A low steady expression of TLR4, MD-2 (zeige LY96 ELISA Kits) and CD14 (zeige CD14 ELISA Kits) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.

  3. In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.

  4. evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins

  5. TLR4/MD-2 (zeige LY96 ELISA Kits) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.

TLR4 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TLR4

  • toll-like receptor 4 (TLR4) Elisa Kit
  • toll-like receptor 4 (Tlr4) Elisa Kit
  • ARMD10 Elisa Kit
  • CD284 Elisa Kit
  • Lps Elisa Kit
  • Ly87 Elisa Kit
  • Ran/M1 Elisa Kit
  • Rasl2-8 Elisa Kit
  • TLR-4 Elisa Kit
  • TOLL Elisa Kit

Bezeichner auf Proteinebene für Toll-Like Receptor 4 (TLR4) ELISA Kits

hToll , homolog of Drosophila toll , lipopolysaccharide response , toll4 , Toll-like receptor4 protein , Toll-like receptor 4-like protein

GENE ID SPEZIES
7099 Homo sapiens
21898 Mus musculus
417241 Gallus gallus
29260 Rattus norvegicus
281536 Bos taurus
100009497 Oryctolagus cuniculus
100724803 Cavia porcellus
403417 Canis lupus familiaris
399541 Sus scrofa
493698 Felis catus
100066890 Equus caballus
100860955 Capra hircus
554263 Ovis aries
100980644 Pan paniscus
100689329 Cricetulus griseus
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