anti-Interferon Regulatory Factor 3 (IRF3) Antikörper

Bezeichnung:
anti-Interferon Regulatory Factor 3 Antikörper (IRF3)
Auf www.antikoerper-online.de finden Sie aktuell 307 Interferon Regulatory Factor 3 (IRF3) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Interferon Regulatory Factor 3 Kits (33) und Interferon Regulatory Factor 3 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 377 Interferon Regulatory Factor 3 Produkte verfügbar.
Synonyme:
C920001K05Rik, IRF-3, IRF3

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Am meisten referenzierte anti-Interferon Regulatory Factor 3 Antikörper

  1. Human Monoclonal IRF3 Primary Antibody für WB - ABIN967306 : Au, Moore, Lowther, Juang, Pitha: Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Zeige alle 8 Referenzen für 967306

  2. Human Monoclonal IRF3 Primary Antibody für Inhibition, IF - ABIN967285 : Darnell, Kerr, Stark: Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. in Science (New York, N.Y.) 1994 (PubMed)
    Zeige alle 8 Referenzen für 967285

  3. Mouse (Murine) Polyclonal IRF3 Primary Antibody für WB - ABIN1881465 : Marichal, Bedoret, Mesnil, Pichavant, Goriely, Trottein, Cataldo, Goldman, Lekeux, Bureau, Desmet: Interferon response factor 3 is essential for house dust mite-induced airway allergy. in The Journal of allergy and clinical immunology 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881465

  4. Human Polyclonal IRF3 Primary Antibody für IF (cc), IF (p) - ABIN742688 : Menasria, Boivin, Lebel, Piret, Gosselin, Boivin: Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection. in Journal of virology 2013 (PubMed)
    Zeige alle 3 Referenzen für 742688

  5. Human Monoclonal IRF3 Primary Antibody für EIA, WB - ABIN317099 : DeFilippis, Robinson, Keck, Hansen, Nelson, Früh: Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection. in Journal of virology 2005 (PubMed)
    Zeige alle 2 Referenzen für 317099

  6. Mouse (Murine) Polyclonal IRF3 Primary Antibody für IHC, WB - ABIN3023115 : Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. in PLoS ONE 2013 (PubMed)

  7. Human Polyclonal IRF3 Primary Antibody für IF (cc), IF (p) - ABIN742695 : Ichikawa, Sugiura, Koarai, Minakata, Kikuchi, Morishita, Oka, Kanai, Kawabata, Hiramatsu, Akamatsu, Hirano, Nakanishi, Matsunaga, Yamamoto, Ichinose: TLR3 activation augments matrix metalloproteinase production through reactive nitrogen species generation in human lung fibroblasts. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

  8. Human Polyclonal IRF3 Primary Antibody für IF (p), IHC (p) - ABIN682588 : Fan, Li, Zhu, Sui, Chen, Deng, Sui, Wang: NF-κB is involved in the LPS-mediated proliferation and apoptosis of MAC-T epithelial cells as part of the subacute ruminal acidosis response in cows. in Biotechnology letters 2016 (PubMed)

  9. Cow (Bovine) Polyclonal IRF3 Primary Antibody für WB - ABIN2779404 : Korherr, Gille, Schäfer, Koenig-Hoffmann, Dixelius, Egland, Pastan, Brinkmann: Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

Weitere Antikörper gegen Interferon Regulatory Factor 3 Interaktionspartner

Zebrafish Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. Following spring viremia of carp (zeige ANKRD1 Antikörper) virus infection, DrIFNPhi1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues, which correlates with the replication of spring viremia of carp (zeige ANKRD1 Antikörper) virus. data provide evidence that fish and mammals have evolved a similar IRF (zeige TRIM63 Antikörper)-dependent regulatory mechanism fine-tuning IFN gene activation.

  2. Interferon (zeige IFNA Antikörper) regulatory factor (IRF (zeige TRIM63 Antikörper))10 inhibits the expression of IFN1 and IFN3 to avoid an excessive immune response, a unique regulation mechanism of the IFN responses in lower vertebrates.

Rhesus Monkey Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. Hepatitis A virus protein 2B suppresses beta interferon (zeige IFNA Antikörper) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Atlantic Salmon (Salmo salar) Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. MyD88 (zeige MYD88 Antikörper) interacts with interferon (zeige IFNA Antikörper) regulatory factor (IRF) 3 and IRF7 (zeige IRF7 Antikörper) in Atlantic salmon (Salmo salar)

Human Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. this study shows that IRF-3-mediated apoptosis of virus-infected cells could be an effective antiviral mechanism, without expression of the interferon (zeige IFNA Antikörper)-stimulated genes

  2. Data in this study show that cFLIPL inhibits IFN regulatory factor 3 (IRF3), a transcription factor central for IFN-beta (zeige IFNB1 Antikörper) and IFN-stimulated gene expression.

  3. 1,8-cineole potentiates the antiviral activity of IRF3 in addition to its inhibitory effect on proinflammatory NF-kappaB (zeige NFKB1 Antikörper) signaling in an ex vivo model of rhinosinusitis.

  4. TBK1 (zeige TBK1 Antikörper) complexes required for the phosphorylation of IRF3 and the production of interferon-beta (zeige IFNB1 Antikörper) have been identified.

  5. RIG-I (zeige DDX58 Antikörper)-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

  6. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 and subsequent type I interferon (zeige IFNA Antikörper) production. (Review)

  7. IRF3 overexpression in Acute myeloid leukemia (zeige BCL11A Antikörper) (AML (zeige RUNX1 Antikörper)) promotes cell growth and survival, and miR (zeige MLXIP Antikörper)-155 is involved, indicating that IRF3 may be a potential new biomarker and therapeutic target for AML (zeige RUNX1 Antikörper).

  8. down-regulation of IRF3 inhibited the proliferation and extracellular matrix expression in keloid fibroblasts.

  9. rotavirus NSP1 (zeige SH2D3A Antikörper) (nonstructural protein 1) employs a pLxIS motif to target IRF-3 for degradation, but phosphorylation of NSP1 (zeige SH2D3A Antikörper) is not required for its activity. These results suggest a concerted mechanism for the recruitment and activation of IRF-3 that can be subverted by viral proteins to evade innate immune responses.

  10. Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta (zeige IFNB1 Antikörper) expression mainly through attenuating IRF-3 phosphorylation.

Pig (Porcine) Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. The authors used recombinant classical swine fever virus N(pro) and swine IRF3 proteins and show that N(pro) interacts with IRF3 directly without additional proteins and forms a soluble 1:1 complex.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 and subsequent degradation of IRF-3, leading to downregulation of IFN-alpha (zeige IFNA Antikörper)/beta production.

  3. The obtained results showed that PRRSV nsp1 could inhibit Poly(I:C)-induced IFN-beta (zeige IFNB1 Antikörper) promoter activity in MARC (zeige CCL7 Antikörper)-145 cells by down-regulating the protein level of IRF-3 and inhibiting the phosphorylation of IRF-3.

  4. proteasomal degradation of IRF3 is induced by a direct or indirect interaction with N(pro).

Mouse (Murine) Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. Findings indicate that STING-TBK1 (zeige TBK1 Antikörper)-IRF3 pathway mediates a crosstalk between ER stress and apoptosis during M. bovis infection, which can effectively control intracellular bacteria.

  2. GPR146 has an antiviral role in fighting against viral infection, although the GPR146-mediated protection is eliminated by IRF3/HES1-signalling.

  3. this study shows that IRF-3-mediated apoptosis of virus-infected cells could be an effective antiviral mechanism, without expression of the interferon (zeige IFNA Antikörper)-stimulated genes

  4. Results establish Irf3, known mostly for its role in antiviral responses, as a transcription factor involved in the induction of Th2 responses through the promotion of pro-Th2 costimulation in CD11b (zeige ITGAM Antikörper)(+) dendritic cells

  5. Rubicon (zeige KIAA0226 Antikörper) specifically interacts with the interferon (zeige IFNA Antikörper) regulatory factor (IRF (zeige TRIM63 Antikörper)) association domain (IAD) of IRF3, and this interaction leads to inhibition of the dimerization of IRF3, which negatively regulates interferon (zeige IFNA Antikörper)-mediated antiviral response.

  6. this study shows that IRF3 in antigen-presenting cells and T cells is required for optimal T-cell effector function and the ability of T cells to influence innate immune function of antigen-presenting cells

  7. The mitochondrial damage-cGAS-STING-IRF3 pathway is critically involved in metabolic stress-induced endothelial inflammation.

  8. TBK1 (zeige TBK1 Antikörper) complexes required for the phosphorylation of IRF3 and the production of interferon-beta (zeige IFNB1 Antikörper) have been identified.

  9. this study shows that lipopolysaccharide priming of dendritic cells stabilizes their tolerogenicity through reduction of NF-kappaB (zeige NFKB1 Antikörper) and IRF3 signaling

  10. this study shows that regulation of the IRF3 pathway can affect multiple cell types and contribute to ameliorate pathogenesis of infection-triggered exacerbation of chronic obstructive pulmonary disease

Cow (Bovine) Interferon Regulatory Factor 3 (IRF3) Interaktionspartner

  1. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta (zeige IFNB1 Antikörper) promoter activity and induces IRF3 degradation.

  2. cpBVDV infection causes a marked loss of interferon regulatory factor 3 (IRF-3), a cellular transcription factor that controls interferon (zeige IFNA Antikörper) synthesis.

Interferon Regulatory Factor 3 (IRF3) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Interferon Regulatory Factor 3 (IRF3)

  • interferon regulatory factor 3 (irf3) Antikörper
  • interferon regulatory factor 3 (IRF3) Antikörper
  • interferon regulatory factor 3 (irf-3) Antikörper
  • interferon regulatory factor 3 (Irf3) Antikörper
  • interferon regulatory factor 7 (IRF7) Antikörper
  • C920001K05Rik Antikörper
  • IRF-3 Antikörper
  • IRF3 Antikörper

Bezeichner auf Proteinebene für IRF3

interferon regulatory factor 3 , interferon regulatory factor 3-like , IRF-3

GENE ID SPEZIES
564854 Danio rerio
718970 Macaca mulatta
747565 Pan troglodytes
780485 Ovis aries
100337625 Salmo salar
100414132 Callithrix jacchus
100441280 Pongo abelii
100471184 Ailuropoda melanoleuca
3661 Homo sapiens
396656 Sus scrofa
54131 Mus musculus
292892 Rattus norvegicus
476412 Canis lupus familiaris
516979 Bos taurus
396330 Gallus gallus
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