anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) Antikörper

Bezeichnung:
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Antikörper (IKBKE)
Auf www.antikoerper-online.de finden Sie aktuell 139 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Proteine (9) und Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 161 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Produkte verfügbar.
Synonyme:
AW558201, IKBKE, IKK-E, IKK-i, IKKE, IKKepsilon, Ikki, MGC130907, zgc:100844
Alle Antikörper anzeigen Gen GeneID UniProt
IKBKE 9641 Q14164
IKBKE 363984  
IKBKE 56489 Q9R0T8

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Am meisten referenzierte anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Antikörper

  1. Human Monoclonal IKBKE Primary Antibody für ELISA, WB - ABIN969213 : Boehm, Zhao, Yao, Kim, Firestein, Dunn, Sjostrom, Garraway, Weremowicz, Richardson, Greulich, Stewart, Mulvey, Shen, Ambrogio, Hirozane-Kishikawa, Hill, Vidal, Meyerson, Grenier, Hinkle, Root et al.: Integrative genomic approaches identify IKBKE as a breast cancer oncogene. ... in Cell 2007 (PubMed)
    Zeige alle 3 Referenzen für 969213

  2. Human Polyclonal IKBKE Primary Antibody für EIA, WB - ABIN116937 : Peters, Liao, Maniatis: IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. in Molecular cell 2000 (PubMed)
    Zeige alle 2 Referenzen für 116937

  3. Human Polyclonal IKBKE Primary Antibody für ICC, IF - ABIN4324307 : Sun, Sammut, Wang, Kurihara, Windle, Roodman, Galson: TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 (PubMed)

  4. Human Polyclonal IKBKE Primary Antibody für IHC (p), WB - ABIN392751 : Blume-Jensen, Hunter: Oncogenic kinase signalling. in Nature 2001 (PubMed)

  5. Human Polyclonal IKBKE Primary Antibody für EIA, IHC (p) - ABIN360635 : Cantrell: Phosphoinositide 3-kinase signalling pathways. in Journal of cell science 2001 (PubMed)

  6. Human Polyclonal IKBKE Primary Antibody für ELISA, IHC - ABIN4324306 : Péant, Diallo, Lessard, Delvoye, Le Page, Saad, Mes-Masson: Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer. in Molecular cancer research : MCR 2007 (PubMed)

Weitere Antikörper gegen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon Interaktionspartner

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) Interaktionspartner

  1. Virus-activated kinase IKKepsilon phosphorylated YAP (zeige YAP1 Antikörper) at Ser403 and thereby triggered degradation of YAP (zeige YAP1 Antikörper) in lysosomes and, consequently, relief of YAP (zeige YAP1 Antikörper)-mediated inhibition of the cellular antiviral response.

  2. We then determined that YAP1 (zeige YAP1 Antikörper) negatively regulates miR (zeige MLXIP Antikörper)-let-7b/i by overexpressing and silencing YAP1 (zeige YAP1 Antikörper) expression. In addition, miR (zeige MLXIP Antikörper)-let-7b/i feedback decreases the expression of IKBKE and YAP1 (zeige YAP1 Antikörper) and suppresses the transportation of YAP1 (zeige YAP1 Antikörper) located in the nucleus. Therefore, the regulatory feedback circuit of IKBKE upward arrow-->YAP1 (zeige YAP1 Antikörper) upward arrow-->miR (zeige MLXIP Antikörper)-let-7b/i downward arrow-->IKBKE upward arrow dictates glioblastoma progress...

  3. our findings highlight the functional importance of IKBKE in pancreatic cancer

  4. we define a pathobiologic function for IKKepsilon in reprogramming glucose metabolism and driving progression in pancreatic ductal adenocarcinoma

  5. demonstrate a key role of TBK1 (zeige TBK1 Antikörper)/IKKepsilon in the survival and proliferation of HTLV-1-transformed T cells

  6. Data suggest that changes in inhibitor of nuclear factor kappa B kinase subunit epsilon (IKKepsilon) and TANK-binding kinase 1 (TBK1 (zeige TBK1 Antikörper)) expression may be involved in the development of intestinal-type gastric cancer.

  7. Live NiV infection, but not a recombinant NiV lacking the M protein (zeige MYOM2 Antikörper), reduced the levels of endogenous TRIM6 (zeige TRIM6 Antikörper) protein expression. To our knowledge, matrix proteins of paramyxoviruses have never been reported to be involved in innate immune antagonism. We report here a novel mechanism of viral innate immune evasion by targeting TRIM6 (zeige TRIM6 Antikörper), IKKepsilon and unanchored polyubiquitin (zeige UBB Antikörper) chains.

  8. The adaptor molecule RAIDD (zeige CRADD Antikörper) coordinates IKKepsilon and IRF7 (zeige IRF7 Antikörper) interaction to ensure efficient expression of type I interferon (zeige IFNA Antikörper).

  9. These findings collectively support the conclusion that IKK (zeige CHUK Antikörper) modulates innate immune signaling cascades via phosphorylating the RIG-I (zeige DDX58 Antikörper) cytosolic sensor, providing a feedback regulatory mechanism.

  10. Blunting of NOX2 (zeige CYBB Antikörper)-dependent IKKepsilon oncogenic kinase expression reduces proliferation and viability of human breast cancer cells.

Mouse (Murine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) Interaktionspartner

  1. Virus-activated kinase IKKepsilon phosphorylated YAP (zeige YAP1 Antikörper) at Ser403 and thereby triggered degradation of YAP (zeige YAP1 Antikörper) in lysosomes and, consequently, relief of YAP (zeige YAP1 Antikörper)-mediated inhibition of the cellular antiviral response.

  2. REGgamma-mediated control of IkappaBvarepsilon contributes to NFkappaB activation and promotes bowel inflammation and associated tumour formation in response to chronic injury

  3. Suggest that by reducing production of cAMP in adipocytes, PDE3B (zeige PDE3B Antikörper), IKKepsilon and TBK1 (zeige TBK1 Antikörper) may contribute to the repression of energy expenditure during obesity.

  4. A role for APPL1 (zeige APPL1 Antikörper) in TLR3 (zeige TLR3 Antikörper)/4-dependent TBK1 (zeige TBK1 Antikörper) and IKKepsilon activation in macrophages.

  5. The results highlight the importance of the C-terminal region in the functional activity of IKKepsilon in innate immune response

  6. tic (zeige ARNTL Antikörper) ablation of IKBKE resulted in enhanced and prolonged priming of the NLRP3 (zeige NLRP3 Antikörper) inflammasome in cultured macrophages, in hypertrophic adipose tissue, and in livers of hypercholesterolemic mice.

  7. novel insight into IKKepsilon, which is involved in adipose tissue inflammation during the development of obesity

  8. miR (zeige MLXIP Antikörper)-339-5p inhibits expression of the pro-inflammatory factors in alcohol-induced brain inflammation through the NF-kappaB (zeige NFKB1 Antikörper) pathway by abolishing IKK-beta (zeige IKBKB Antikörper) and IKK-epsilon activity.

  9. IKKepsilon deficiency inhibits inflammation and induces cardiac protection in high-fat diet-induced obesity in mice.

  10. IKKepsilon is expressed in neurons and is upregulated in the hypothalamus of obese mice, contributing to insulin (zeige INS Antikörper) and leptin (zeige LEP Antikörper) resistance.

Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) Antigen-Profil

Beschreibung des Gens

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009

Alternative names and synonyms associated with Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE)

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE) Antikörper
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (ikbke) Antikörper
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (Ikbke) Antikörper
  • inhibitor of kappaB kinase epsilon (Ikbke) Antikörper
  • AW558201 Antikörper
  • IKBKE Antikörper
  • IKK-E Antikörper
  • IKK-i Antikörper
  • IKKE Antikörper
  • IKKepsilon Antikörper
  • Ikki Antikörper
  • MGC130907 Antikörper
  • zgc:100844 Antikörper

Bezeichner auf Proteinebene für IKBKE

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon , IKKe , inhibitor of nuclear factor kappa-B kinase subunit epsilon , inhibitor of nuclear factor kappa-B kinase subunit epsilon-like , I-kappa-B kinase epsilon , IKK-epsilon , IKK-related kinase epsilon , inducible I kappa-B kinase , inducible IkappaB kinase , inhibitor of kappaB kinase epsilon , IKK-E , inducible IKappaB kinase

GENE ID SPEZIES
430480 Gallus gallus
437024 Danio rerio
478950 Canis lupus familiaris
695607 Macaca mulatta
734896 Xenopus laevis
742813 Pan troglodytes
100019578 Monodelphis domestica
100055384 Equus caballus
100077063 Ornithorhynchus anatinus
100448480 Pongo abelii
100519508 Sus scrofa
100548215 Meleagris gallopavo
100562496 Anolis carolinensis
9641 Homo sapiens
533216 Bos taurus
363984 Rattus norvegicus
56489 Mus musculus
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