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Kaninchen ''B'' (1-2 Lbs.) Complement (Lyophilized) With Diluent

Wirt: Kaninchen
Produktnummer ABIN925152
  • Wirt
    Kaninchen
    Spezifität
    The complement system consists of a number of small proteins found in the blood, generally synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 25 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum.
    Produktmerkmale
    Strain: Rabbit - New Zealand White
    Sex: Mixed
    Aufreinigung
    Complement
    Sterilität
    Non-sterile
    Bestandteile
    with Diluent
  • Applikationshinweise
    pH: normal Immunoelectrophoresis: normal Hemoglobin: normal IgG Concentration: normal Immunoelectrophoresis: normal
    Kommentare

    The rabbit complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. Complement is part of the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. Complement can be recruited and brought into action by the adaptive immune system. The following are basic functions of complement: 1. Opsonisation - enhancing phagocytosis of antigens 2. Chemotaxis - attracting macrophages and neutrophils 3. Cell Lysis - rupturing membranes of foreign cells 4. Clumping of antigen-bearing agents

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen
    Rekonstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 5.0 mL
    Konzentration
    85 mg/mL
    Handhabung
    Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. COMPLEMENT IS A TEMPERATURE SENSITIVE PRODUCT. IMPROPER STORAGE WILL INACTIVATE COMPLEMENT ACTIVITY.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Hintergrund
    The rabbit complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. Complement is part of the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. Complement can be recruited and brought into action by the adaptive immune system. The following are basic functions of complement: 1. Opsonisation - enhancing phagocytosis of antigens 2. Chemotaxis - attracting macrophages and neutrophils 3. Cell Lysis - rupturing membranes of foreign cells 4. Clumping of antigen-bearing agents
    Synonyms: Complement system, tissue macrophages, blood monocytes, protease C3-convertase, mannose-binding lectin pathway, C3, C3a, C3b, C5a, C5b, C6, C7, C8, and polymeric C9, cascade cleavage and activation events, recruit inflammatory cells, anaphylatoxin.
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