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Human GPX3 ELISA Kit für Sandwich ELISA - ABIN418700
Choi, Cho, Seo, Park, Kim, Lee: Alteration of the intrafollicular thiol-redox system in infertile women with endometriosis. in Reproduction (Cambridge, England) 2014
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Results indicate that selenoprotein P (Sepp1 (zeige SEPP1 ELISA Kits)) is important for this transport in selenium-replete mice but that glutathione peroxidase-3 (Gpx3) is not.
GPx3 may have a possible role in modulating prostate carcinogenesis.
Sepp1 (zeige SEPP1 ELISA Kits)(UF) and small selenium-containing proteins are filtered by the glomerulus and taken up by PCT (zeige UROD ELISA Kits) cells via megalin (zeige LRP2 ELISA Kits)-mediated endocytosis, preventing loss of selenium in the urine and providing selenium for the synthesis of glutathione peroxidase-3
GPX3 may play a major role in reducing hydrogen peroxide during decidualization.
Data indicate that uptake of Sepp1 (zeige SEPP1 ELISA Kits) and Gpx3 by d-13 visceral yolk sac (zeige ADCY10 ELISA Kits) was independent of apoER2 (zeige LRP8 ELISA Kits) and megalin (zeige LRP2 ELISA Kits).
an immunomodulatory role for GPX3 that limits the development of colitis-associated carcinoma.
We applied X-ray fluorescence microscopy to image selenium in mammalian tissues and identified a highly localized pool of this trace element at the basement membrane of kidneys that was associated with GPx3
These results show that glutathione peroxidase 3 from the blood binds to basement membranes of specific epithelial cells and indicate that the cells modify their basement membranes to cause the binding.
GPx-3 deficiency results in a prothrombotic state and vascular dysfunction that promotes platelet-dependent arterial thrombosis
Gpx3 and ERalpha (zeige ESR1 ELISA Kits) gene expression are sensitive to circulating estrogens in skeletal muscle
Study provides evidence that GPX3 methylation in bone marrow is associated with adverse prognosis and leukemia transformation in myelodysplastic syndrome.
this paper shows that GPx3 expression can be regulated independently via epigenetic or glucocorticoid receptor (zeige NR3C1 ELISA Kits)-mediated mechanisms in lung cancer cells
negative expression of GPX3 was related to poor prognosis in melanoma patients. These results suggest that methylation-mediated GPX3 repression may have critical implications for melanoma pathogenesis
The detection of the demethylated allele could be time and phe concentration dependent. The demethylated allele is suggested as an early epigenetic marker for an extracellular monitoring of an increased ROS production in newborns with PKU.
GPX1 (zeige GPX1 ELISA Kits)*Pro198Leu AND GPX3 rs2070593 as genetic risk markers for Italian asthmatic patients
A three-way interaction among maternal and fetal variants in BHMT2 (zeige BHMT2 ELISA Kits), GSTP1 (zeige GSTP1 ELISA Kits) and GPX3 contribute to congenital heart defects
GPX3 hypermethylation is frequent in chronic myeloid leukemia (zeige BCL11A ELISA Kits) and is negatively associated with its expression.
Reduced GPX3 expression is associated with favorable/intermediate karyotypes but not with survival in de novo acute myeloid leukemia (zeige BCL11A ELISA Kits) patients.
GPX1, GPX3, and GPX4 genes may play a role in clear cell renal cell carcinoma cancerogenesis.
GPX3 is frequently methylated in human papillary thyroid cancer and the expression of GPX3 was regulated by promoter region methylation
Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 ELISA Kits) and PTGS2 (zeige PTGS2 ELISA Kits), and decreased the expression of SOD2 (zeige SOD2 ELISA Kits), GPX3, DAB2 (zeige DAB2 ELISA Kits), and NR3C1 (zeige NR3C1 ELISA Kits). TNF (zeige TNF ELISA Kits) and IL6 (zeige IL6 ELISA Kits) levels were also decreased while those of NAMPT (zeige NAMPT ELISA Kits) were unaffected.
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
glutathione peroxidase 3 (plasma)
, extracellular GPx
, plasma GPx
, plasma glutathione peroxidase
, extracellular glutathione peroxidase
, glutathione peroxidase 3