anti-H2A Histone Family, Member X (H2AFX) Antikörper

Bezeichnung:
anti-H2A Histone Family, Member X Antikörper (H2AFX)
Auf www.antikoerper-online.de finden Sie aktuell 344 H2A Histone Family, Member X (H2AFX) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen H2A Histone Family, Member X Kits (19) und H2A Histone Family, Member X Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 385 H2A Histone Family, Member X Produkte verfügbar.
Synonyme:
AW228881, gammaH2ax, h2a, h2a.x, h2a/x, h2afx, h2ax, Hist5-2ax, RGD1566119, zgc:56329
Alle Antikörper anzeigen Gen GeneID UniProt
H2AFX 3014 P16104
H2AFX 15270 P27661
H2AFX 500987  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

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Am meisten referenzierte anti-H2A Histone Family, Member X Antikörper

  1. Human Polyclonal H2AFX Primary Antibody für ICC, IF - ABIN151847 : Masutomi, Possemato, Wong, Currier, Tothova, Manola, Ganesan, Lansdorp, Collins, Hahn: The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Zeige alle 10 Referenzen für 151847

  2. Human Monoclonal H2AFX Primary Antibody für WB - ABIN1882251 : Park, Chan, Park, Oettinger, Kwon: DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner. in Nucleic acids research 2003 (PubMed)
    Zeige alle 5 Referenzen für 1882251

  3. Human Monoclonal H2AFX Primary Antibody für BI, WB - ABIN967669 : Burma, Chen, Murphy, Kurimasa, Chen: ATM phosphorylates histone H2AX in response to DNA double-strand breaks. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 5 Referenzen für 967669

  4. Human Monoclonal H2AFX Primary Antibody für WB - ABIN1882250 : Stiff, ODriscoll, Rief, Iwabuchi, Löbrich, Jeggo: ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. in Cancer research 2004 (PubMed)
    Zeige alle 5 Referenzen für 1882250

  5. Human Polyclonal H2AFX Primary Antibody für ICC, IF - ABIN2668328 : Velichko, Petrova, Kantidze, Razin: Dual effect of heat shock on DNA replication and genome integrity. in Molecular biology of the cell 2012 (PubMed)
    Zeige alle 3 Referenzen für 2668328

  6. Human Polyclonal H2AFX Primary Antibody für IHC (p), WB - ABIN657639 : Jiang, Xu, Price: Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway. in FEBS letters 2010 (PubMed)
    Zeige alle 3 Referenzen für 657639

  7. Cow (Bovine) Polyclonal H2AFX Primary Antibody für WB - ABIN2787619 : Scherthan, Hieber, Braselmann, Meineke, Zitzelsberger: Accumulation of DSBs in gamma-H2AX domains fuel chromosomal aberrations. in Biochemical and biophysical research communications 2008 (PubMed)
    Zeige alle 2 Referenzen für 2787619

  8. Human Polyclonal H2AFX Primary Antibody für IF (p), IHC (p) - ABIN742538 : Shi, Yang, Mao, Wu, Ren, Yang, Yin, Wei, Li, Wang: Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation. in Acta pharmacologica Sinica 2015 (PubMed)
    Zeige alle 2 Referenzen für 742538

  9. Human Polyclonal H2AFX Primary Antibody für IHC, ELISA - ABIN1532893 : Tyagi, Singh, Agarwal, Siriwardana, Sclafani, Agarwal: Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. in Carcinogenesis 2005 (PubMed)

Weitere Antikörper gegen H2A Histone Family, Member X Interaktionspartner

Human H2A Histone Family, Member X (H2AFX) Interaktionspartner

  1. Cyclin F (zeige CCNF Antikörper)-mediated degradation of SLBP (zeige SLBP Antikörper) limits H2A.X accumulation and apoptosis upon genotoxic stress in G2 cell cycle checkpoint.

  2. study demonstrates that the individual and combined expression patterns of the DDR (zeige DDR1 Antikörper) molecules PARP1 (zeige PARP1 Antikörper), gammaH2AX, BRCA1, and BRCA2 (zeige BRCA2 Antikörper) could be predictive of the prognosis of STS (zeige STS Antikörper) patients and suggests that controlling the activity of these DDR (zeige DDR1 Antikörper) molecules could be employed in new therapeutic stratagems for the treatment of STS (zeige STS Antikörper)

  3. Further analysis suggested that H2AX, a PARP-1 (zeige PARP1 Antikörper) protein interaction partner, was coordinated with PARP-1 (zeige PARP1 Antikörper) in hepatocellular carcinoma tumorigenesis. Overall, some new characteristics of PARP-1 (zeige PARP1 Antikörper) expression were noted in the Zhuang population. PARP-1 (zeige PARP1 Antikörper) is a novel promising diagnostic marker for hepatocellular carcinoma in the Southern Chinese Zhuang population

  4. we found that gamma-H2AX foci at chromosome boundaries after carbon-ion irradiation contain DNA double strand breaks undergoing DNA-end resection, which promotes repair utilizing microhomology mediated end-joining during translocation.

  5. this study demonstrates an early DDR (zeige DDR1 Antikörper) defect of attenuated gammaH2AX signals in G0/G1 phase HGPS (zeige Zmpste24 Antikörper) cells and provides a plausible connection between H3K9me3 loss and DDR (zeige DDR1 Antikörper) deficiency.

  6. Data indicate an important role for histone H2A.X (H2AX) Tyr39 phosphorylation in gamma-H2A.X formation and cancer progression.

  7. we suggest that the XAB2 (zeige XAB2 Antikörper) complex mediates DNA damage response events important for the end resection step of homologous recombination , and speculate that its adjacent-localization relative to double-strand break marked by gH2AX is important for this function

  8. the epithelial-mesenchymal transition-related transcription factor Twist1 (zeige TWIST1 Antikörper) cooperates with Slug (zeige SNAI2 Antikörper) to regulate EMT (zeige ITK Antikörper) upon H2A.X Loss.

  9. Upon DNA damage, an increase in the levels of chromatin bound motor protein nuclear myosin 1 (NM1 (zeige MYO1C Antikörper)) ensues, which appears to be functionally linked to Upsilon-H2AX signaling.

  10. TRAF6 (zeige TRAF6 Antikörper) and H2AX overexpression and gammaH2AX-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

Mouse (Murine) H2A Histone Family, Member X (H2AFX) Interaktionspartner

  1. The authors observe that persistent accumulation of reactive oxygen species, due to a deficient JunD-/Nrf2-antioxidant response, reduces H2AX protein levels. This effect is mediated by an enhanced interaction of H2AX with the E3 ubiquitin ligase RNF168, which is associated with H2AX poly-ubiquitination and promotes its degradation by the proteasome.

  2. TRAF6 (zeige TRAF6 Antikörper) and H2AX overexpression and gammaH2AX-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

  3. The findings highlight specific non-overlapping functions of PARP1 (zeige PARP1 Antikörper) and PARP2 (zeige PARP2 Antikörper) at H2AX-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 (zeige PARP1 Antikörper) in nonhomologous end-joining-deficient cells.

  4. Unlike directly induced DSBs, secondary DSBs were not efficiently repaired, although Rad51 (zeige RAD51 Antikörper) and 53BP1 (zeige TP53BP1 Antikörper) were recruited to these sites. H2AX was dramatically stabilized in response to DSBs directly caused by gamma-rays, enabling gammaH2AX foci formation and DSB repair, whereas H2AX was barely stabilized in response to secondary DSBs, in which gammaH2AX foci were small and DSBs were not efficiently repaired

  5. this study shows that T cells and thyrocytes in a mouse model of thyrocyte hyperplasia has foci of phosphorylated histone protein H2A.X, indicative of cellular senescence

  6. The role of H2AX phosphorylation and H3K56 acetylation on normal stem cell response to radiation

  7. H2AX knockout mice showed cell-autonomous anaemia and erythroid dysplasia, mimicking dyserythropoiesis in MDS (zeige MECOM Antikörper).

  8. These data suggest a role for FoxO3a in the maintenance of genome integrity in response to DNA damage that is mediated by H2AX via yet unknown mechanisms.

  9. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

  10. link gamma-H2AX to transcription, assigning a new function for this DNA damage marker

Xenopus laevis H2A Histone Family, Member X (H2AFX) Interaktionspartner

  1. These findings suggest a dimerize-then-rearrange model for H2A-H2B dimers.

  2. Findings reveal that XH2AX has a specific role in anterior neural formation of Xenopus, which is mediated through phosphorylation of XH2AX at Thr (zeige TRH Antikörper)(16) by Chk1 (zeige CHEK1 Antikörper).

Cow (Bovine) H2A Histone Family, Member X (H2AFX) Interaktionspartner

  1. H2Ax phosphorylated protein was detected in in parthenogenetically activated, in vitro fertilized and cloned bovine embryos.

H2A Histone Family, Member X (H2AFX) Antigen-Profil

Beschreibung des Gens

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Alternative names and synonyms associated with H2A Histone Family, Member X (H2AFX)

  • H2A histone family, member X (H2AFX) Antikörper
  • H2A histone family, member X (H2afx) Antikörper
  • H2A histone family, member X (h2afx) Antikörper
  • histone cluster 1, H2ah (HIST1H2AH) Antikörper
  • histone cluster 2, H2ab (hist2h2ab) Antikörper
  • histone H2A.x-like (LOC100522201) Antikörper
  • histone H2A.x-like (LOC100720536) Antikörper
  • AW228881 Antikörper
  • gammaH2ax Antikörper
  • h2a Antikörper
  • h2a.x Antikörper
  • h2a/x Antikörper
  • h2afx Antikörper
  • h2ax Antikörper
  • Hist5-2ax Antikörper
  • RGD1566119 Antikörper
  • zgc:56329 Antikörper

Bezeichner auf Proteinebene für H2AFX

H2AX histone , histone H2A.x , H2a/x , histone 5 protein 2ax , H2A.X , histone H2A type 1

GENE ID SPEZIES
3014 Homo sapiens
15270 Mus musculus
394048 Danio rerio
734746 Xenopus laevis
531733 Bos taurus
500987 Rattus norvegicus
418708 Gallus gallus
444528 Xenopus laevis
100522201 Sus scrofa
100720536 Cavia porcellus
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