VAV1 Proteine (VAV1)

Auf www.antikoerper-online.de finden Sie aktuell 7 Vav 1 Oncogene (VAV1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen VAV1 Antikörper (169) und VAV1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 185 VAV1 Produkte verfügbar.
Synonyme:
Vav, vav-T
alle Proteine anzeigen Gen GeneID UniProt
VAV1 7409 P15498
Ratte VAV1 VAV1 25156  
VAV1 22324 P27870

VAV1 Proteine (VAV1) nach Spezies

Weitere Proteine zu VAV1 Interaktionspartnern

Human Vav 1 Oncogene (VAV1) Interaktionspartner

  1. Polymorphisms of VAV1 gene is associated with Rheumatoid arthritis.

  2. Vav1 expression is increased in esophageal squamous cell carcinoma, indicates poor prognosis, and can serve as a candidate molecular prognostic marker.

  3. TGFbeta (zeige TGFB1 Proteine) induced the dissociation of DNMT1 (zeige DNMT1 Proteine) from the VAV1 promoter, leading to demethylation and the subsequent ectopic expression of VAV1 in cancer cells via a SMAD4 (zeige SMAD4 Proteine)-dependent mechanism

  4. Our results suggest the existence of a Vav1/PU.1/miR (zeige MLXIP Proteine)-142-3p network that supports all-trans retinoic acid -induced differentiation in acute promyelocytic leukemia (zeige PML Proteine) -derived cells

  5. revealed a new function for Vav1 in the negative feedback regulation of the phosphorylation of immunoreceptor tyrosine-based activation motifs within the zeta chains, CD3 delta (zeige CD3D Proteine), epsilon, gamma chains, as well as activation sites on the critical T cell tyrosine kinases

  6. Data indicate that only a single mutation in the proto-oncogene (zeige RAB1A Proteine) Vav1 enhances tumorigenicity.

  7. These findings establish VAV1 as a critical epigenetically regulated oncogene (zeige RAB1A Proteine) with a key role in MBSHH maintenance, and highlight its potential as a validated therapeutic target and prognostic biomarker for the improved therapy of medulloblastoma.

  8. The present study implies that estrogen-estrogen receptor (zeige ESR1 Proteine) modulates the transcription and expression of Vav1, which may contribute to the proliferation of cancerous cells.

  9. The role of Vav1 in T leukemia survival by selectively triggering Rac2 (zeige RAC2 Proteine)-Akt (zeige AKT1 Proteine) axis and elevating the expression of anti-apoptotic Bcl-2 (zeige BCL2 Proteine).

  10. results presented herein suggest a potential cross-talk between cancer cells and the microenvironment controlled by CSF1 (zeige CSF1 Proteine)/Vav1 signaling pathways.

Mouse (Murine) Vav 1 Oncogene (VAV1) Interaktionspartner

  1. Vav1 adaptor has a role in the production of inflammatory cytokines by effector T cells and in the susceptibility to neuroinflammation

  2. provide evidence that CD28 (zeige CD28 Proteine) and the TCR complex regulate NF-kappaB (zeige NFKB1 Proteine) via different signaling modules of GRB-2 (zeige GRB2 Proteine)/VAV1 and LAT (zeige LAT Proteine)/ADAP (zeige APP Proteine) pathways respectively.

  3. Platelet P-Rex and Vav family Rac (zeige AKT1 Proteine)-GEFs play important proinflammatory roles in leukocyte recruitment.

  4. The data show that vav1 not only affects transcription of the MHCII locus but also is an important regulator of MHCII protein transport to the cell surface.

  5. analyses revealed a SHP2 (zeige PTPN11 Proteine)- and Lyn (zeige LYN Proteine)-dependent pathway leading to phosphorylation of Vav1, Rac (zeige AKT1 Proteine) activation, and F-actin polymerization in SCF (zeige KITLG Proteine)-treated BMMCs

  6. Data indicate that Vav1 was a key negative regulator of macrophage-derived IL-6 (zeige IL6 Proteine) production.

  7. Bruton's Tyrosine Kinase (BTK (zeige BTK Proteine)) and Vav1 contribute to Dectin1 (zeige CLEC7A Proteine)-dependent phagocytosis of Candida albicans in macrophages.

  8. Suggest that Vav1 act as critical molecular link coupling hyperlipidemia with proatherogenic monocyte/macrophage responses.

  9. Loss of Vav1 activity does not favour development of colitis-associated colon cancer.

  10. SH2 and SH3(B) domains of Vav1 are critical for the phosphorylation of Vav1 and its signalling function in TCR-induced calcium flux.

VAV1 Protein Überblick

Protein Überblick

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with VAV1

  • vav 1 guanine nucleotide exchange factor (VAV1)
  • vav 1 guanine nucleotide exchange factor (Vav1)
  • vav 1 oncogene (Vav1)
  • vav 1 oncogene (vav1)
  • Vav Protein
  • vav-T Protein

Bezeichner auf Proteinebene für Vav 1 Oncogene Proteine (VAV1)

vav 1 oncogene , proto-oncogene vav , p95 , p95vav , vav oncogene

GENE ID SPEZIES
455647 Pan troglodytes
7409 Homo sapiens
25156 Rattus norvegicus
485016 Canis lupus familiaris
617345 Bos taurus
100519821 Sus scrofa
22324 Mus musculus
446826 Xenopus laevis
Ausgewählte Anbieter für VAV1 Proteine (VAV1)
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