Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Proteine (SLC25A20)

Bezeichnung:
Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Proteine (SLC25A20)
Auf www.antikoerper-online.de finden Sie aktuell 6 Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Antikörper (57) und Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Kits (34) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 102 Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Produkte verfügbar.
Synonyme:
5848, 1110007P09Rik, BG:DS02740.15, C78826, CAC, cact, CG5848, dif-1, dip6, DKFZp468F1219, Dmel\\CG5848, fs(2)ltoRN48, mCAC, n(2)k17003, PRKAR2A, SLC25A20, zgc:77760
alle Proteine anzeigen Gen GeneID UniProt
SLC25A20 117035  
SLC25A20 788 O43772
SLC25A20 57279 Q9Z2Z6

Weitere Synonyme anzeigen

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Weitere Proteine zu Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Interaktionspartner

  1. It has been shown that Dorsal repressed Ush expression levels to promote hemocytes differentiation, whereas Cactus maintained Ush levels to block differentiation.

  2. CalpA targets free Cactus, which is incorporated into and modulates Toll (zeige TLR4 Proteine)-responsive complexes in the embryo and immune system.

  3. Dorsal and Cactus maybe necessary for normal function and maintenance of the neuromuscular system. These proteins can respond to synaptic activity.

  4. Cactus acts as an inhibitor of the Rel-transcription factors Dorsal and Dif (zeige TNF Proteine).

  5. immune-induced degradation does not require CSN5 (zeige COPS5 Proteine)

  6. Dpp signals increase Cactus levels through Calpain A inhibition, thereby interfering with Dorsal activation

Human Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Interaktionspartner

  1. The antiport mode of transport, typical of mitochondrial carriers such as CAC (zeige CA2 Proteine), results from coupling of uniport reactions in opposite directions mediated by specific amino acid residues.

  2. C.576G>A, c.106-2a>t and c.516T>C are novel CACT gene mutations.

  3. CPT2 (zeige CPT2 Proteine) and CACT are crucial for mitochondrial acylcarnitine formation and export to the extracellular fluids in mitochondrial fatty acid beta-oxidation disorders.

  4. Compares and contrasts all the known human SLC25A (zeige SLC25A25 Proteine)* genes and includes functional information.

  5. Results show Steroid Receptor Coactivator (zeige SRA1 Proteine)-3 (SRC-3 (zeige NCOA3 Proteine)) plays a central role in long chain fatty acid metabolism by directly regulating carnitine/acyl-carnitine translocase (CACT) gene expression.

  6. These results show that FOXA and Sp1 (zeige PSG1 Proteine) sites in HepG2 cells and only the Sp1 (zeige PSG1 Proteine) site in HEK293 and SK-N-SH cells have a critical role in the transcriptional regulation of the CAC (zeige CA2 Proteine) proximal promoter.

  7. A deficiency in CACT was treated with a carnitine diet and administration of medium-chain triglycerides.

  8. The clinical, biochemical, & molecular features of 6 CACT-deficient patients from Italy, Spain, & North America who had significant clinical heterogeneity are reported. 5 novel & 3 previously reported mutations were found.

  9. The modulation of CACT expression has consequences for CPT 1 (zeige CPT1A Proteine) activity, while the biologic effects of acetyl-carnitine are not associated with a generic supply of energy compounds but to the anaplerotic property of the molecule.

  10. Report the outcome of two siblings with CACT deficiency.

Mouse (Murine) Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Interaktionspartner

  1. the 50-flanking region of the Cact gene contains a consensus sequence for ERRalpha (zeige ESRRA Proteine). This sequence binds ERRa (zeige ESRRA Proteine) both in vivo and in vitro and is required for the activation of Cact expression by the PGC-1/ERR (zeige SLC7A1 Proteine) axis

  2. Data show that the upregulation of CACT by PPARalpha (zeige PPARA Proteine) and PPARdelta (zeige PPARD Proteine) may increase the import of acylcarnitine into the mitochondrial matrix during fasting.

Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Protein Überblick

Protein Überblick

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Alternative names and synonyms associated with Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20)

  • cactus (cact)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (slc25a20)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (SLC25A20)
  • carnitine/acylcarnitine translocase (LOC100352079)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (Slc25a20)
  • protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A)
  • solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 (Slc25a20)
  • 5848 Protein
  • 1110007P09Rik Protein
  • BG:DS02740.15 Protein
  • C78826 Protein
  • CAC Protein
  • cact Protein
  • CG5848 Protein
  • dif-1 Protein
  • dip6 Protein
  • DKFZp468F1219 Protein
  • Dmel\\CG5848 Protein
  • fs(2)ltoRN48 Protein
  • mCAC Protein
  • n(2)k17003 Protein
  • PRKAR2A Protein
  • SLC25A20 Protein
  • zgc:77760 Protein

Bezeichner auf Proteinebene für SLC25A20

CG5848-PA , CG5848-PB , CG5848-PC , CG5848-PD , CG5848-PE , NF-kappa-B inhibitor cactus , cact-PA , cact-PB , cact-PC , cact-PD , cact-PE , female-sterile-(2)-ltoRN48 , solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 , carnitine/acylcarnitine translocase , CAC , mitochondrial carnitine/acylcarnitine carrier protein , solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 , solute carrier family 25 member 20 , protein kinase, cAMP-dependent, regulatory, type II, alpha , carnitine/acylcarnitine carrier protein , mitochondrial carnitine-acylcarnitine translocase

GENE ID SPEZIES
34969 Drosophila melanogaster
779503 Xenopus (Silurana) tropicalis
460354 Pan troglodytes
709029 Macaca mulatta
100147786 Ovis aries
100173532 Pongo abelii
100352079 Oryctolagus cuniculus
117035 Rattus norvegicus
393833 Danio rerio
380111 Xenopus laevis
416062 Gallus gallus
788 Homo sapiens
484774 Canis lupus familiaris
518758 Bos taurus
57279 Mus musculus
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