anti-PRKCE (PRKCE) Antikörper

Bezeichnung:
anti-Protein Kinase C, epsilon Antikörper (PRKCE)
Auf www.antikoerper-online.de finden Sie aktuell 193 Protein Kinase C, epsilon (PRKCE) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PRKCE Kits (50) und PRKCE Proteine (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 273 PRKCE Produkte verfügbar.
Synonyme:
5830406C15Rik, fj59b07, nPKC-epsilon, pkc-epsilon, Pkce, PKCepsilon, PKC[e], prkce, PRKCH, R75156, wu:fj59b07

Meistgesuchte Reaktivitäten zu anti-PRKCE (PRKCE) Antikörper

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anti-Human PRKCE Antikörper:

anti-Mouse (Murine) PRKCE Antikörper:

anti-Rat (Rattus) PRKCE Antikörper:

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Am meisten referenzierte anti-PRKCE Antikörper

  1. Chicken Monoclonal PRKCE Primary Antibody für IF, IP - ABIN967734 : Balafanova, Bolli, Zhang, Zheng, Pass, Bhatnagar, Tang, Wang, Cardwell, Ping: Nitric oxide (NO) induces nitration of protein kinase Cepsilon (PKCepsilon ), facilitating PKCepsilon translocation via enhanced PKCepsilon -RACK2 interactions: a novel mechanism of no-triggered activation of PKCepsilon. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 6 Referenzen für 967734

  2. Human Polyclonal PRKCE Primary Antibody für EIA, IHC (p) - ABIN359064 : Gray, Zhou, Schafhalter-Zoppoth, Zhu, Mochly-Rosen, Messing: Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon. in The Journal of biological chemistry 2004 (PubMed)
    Zeige alle 5 Referenzen für 359064

  3. Human Polyclonal PRKCE Primary Antibody für IHC (p), WB - ABIN391007 : Tang, Bouyer, Mykoniatis, Buschmann, Matlin, Matthews: Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. in The Journal of biological chemistry 2010 (PubMed)

  4. Human Polyclonal PRKCE Primary Antibody für ELISA, WB - ABIN1532522 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

Weitere Antikörper gegen PRKCE Interaktionspartner

Human Protein Kinase C, epsilon (PRKCE) Interaktionspartner

  1. PKCdelta (zeige PKCd Antikörper) and PKCepsilon work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.

  2. Curcumin inhibited phorbol ester-induced membrane translocation of protein kinase C-epsilon (PKCepsilon) mutants, in which the epsilonC1 domain was replaced with alphaC1, but not the protein kinase C-alpha (PKCalpha (zeige PKCa Antikörper)) mutant in which alphaC1 was replaced with the epsilonC1 domain, suggesting that alphaC1 is a determinant for curcumin's inhibitory effect.

  3. we demonstrate that PKCepsilon cooperates with the loss of the tumor suppressor Pten (zeige PTEN Antikörper) for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe overexpression and Pten (zeige PTEN Antikörper) loss individually and synergistically upregulate the production of the chemokine (zeige CCL1 Antikörper) CXCL13 (zeige CXCL13 Antikörper), which involves the transcriptional activation of the CXCL13 (zeige CXCL13 Antikörper) gene

  4. These results indicate that PKC (zeige PRRT2 Antikörper) promotes synaptogenesis by activating PSD-95 (zeige DLG4 Antikörper) phosphorylation directly through JNK1 (zeige MAPK8 Antikörper) and calcium/calmodulin-dependent kinase (zeige CAMK2 Antikörper) II and also by inducing expression of PSD-95 (zeige DLG4 Antikörper) and synaptophysin (zeige SYP Antikörper).

  5. epsilonPKC phosphorylation and its coevolution with ALDH2 (zeige ALDH2 Antikörper) play an important role in the regulation and protection of ALDH2 (zeige ALDH2 Antikörper) enzyme activity.

  6. PKCepsilon down-regulation suppresses sorting and the cancer stem-like phenotype of renal cell carcinoma (zeige MOK Antikörper) 769P side population cells through the regulation of ABCB1 (zeige ABCB1 Antikörper) transporter and the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper), Stat3 (zeige STAT3 Antikörper) and MAPK/ERK (zeige MAPK1 Antikörper) pathways that are dependent on the phosphorylation effects.

  7. PRKCE plays two major roles in cardiac muscle cells: it takes part in regulating cardiac muscle contraction via targeting the sarcomeric proteins, as well as it modulates cardiac cell energy production and metabolism by targeting cardiac mitochondria. (Review)

  8. PKCepsilon is a key factor for driving the formation of bone metastasis by prostate cancer cells and is a potential therapeutic target for advanced stages of the disease.

  9. Docosahexaenoic acid increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt (zeige AKT1 Antikörper) and PKCepsilon/delta-induced ERK (zeige EPHB2 Antikörper) pathways.

  10. Depletion of PKCepsilon not only enhanced HGF-induced phosphorylation of JNK and paxillin (Ser178) but also prevented c-Met degradation.

Mouse (Murine) Protein Kinase C, epsilon (PRKCE) Interaktionspartner

  1. that PKC-epsilon activation mediates 1) dysfunction of complexes I and III of the respiratory chain, 2) oxidant production, 3) morphological damage to the kidney, and 4) decreases in renal functions after ischemia

  2. Sstudy provides evidence that PKCepsilon-ALDH2 (zeige ALDH2 Antikörper) pathway positively regulates adipocyte differentiation by regulation of PPARgamma (zeige PPARG Antikörper) transcriptional activity.

  3. Data suggest that PKCe positively regulates beta-catenin (zeige CTNNB1 Antikörper) expression and stabilization in a glycogen synthase kinase 3beta-independent manner; beta-catenin (zeige CTNNB1 Antikörper) exhibits a perinuclear localization pattern in podocytes; however, beta-catenin (zeige CTNNB1 Antikörper) is predominantly localized to nucleus in podocytes from PKCe knockout mice. (PKCe = protein kinase C epsilon)

  4. Results demonstrate that specific inhibition of PKCepsilon reduces ethanol consumption and prolongs ethanol intoxication, support the development of inhibitors of PKCepsilon catalytic activity as a strategy to reduce ethanol consumption, and they demonstrate that the AS- PKCepsilon mouse is a useful tool to study the role of PKCepsilon in behavior.

  5. inhibition of mu-opioid receptor expression blocks morphine and DAMGO increases in the translocation of NF-kB p65 protein in microglia.a low dose of morphine, exerting its effects via the mu-opioid receptor, increases the DNA-binding activity of NF-kB via PKCepsilon, while a high dose of morphine triggers a nonopiate receptor response mediated by TLR4 and, interestingly, PKC signalling

  6. PKCepsilon signaling in both the nucleus accumbens and central nucleus of the amygdala is a major contributor to binge alcohol drinking and to the genetic propensity to consume excessive amounts of alcohol.

  7. with strain there was significant PKCepsilon translocation to the Z-disc and co-localization with CapZbeta1 or alpha-actinin (zeige ACTN1 Antikörper), which was quantified on confocal images.

  8. Protein kinase C epsilon phosphorylates the alpha4 nAChR (zeige CHRNA4 Antikörper) subunit and regulates recovery from receptor desensitization.

  9. PKCepsilon-CREB (zeige CREB1 Antikörper)-Nrf2 (zeige NFE2L2 Antikörper) signalling induces HO-1 (zeige HMOX1 Antikörper) in the vascular endothelium and enhances resistance to inflammation and apoptosis.

  10. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

Cow (Bovine) Protein Kinase C, epsilon (PRKCE) Interaktionspartner

  1. These data identify PKCepsilon as a key regulator of cilia slowing in response to combined smoke and alcohol-induced lung injury.

  2. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (zeige NOS3 Antikörper) post-translational modification

  3. Differential expression of protein kinase C epsilon and an elevation of [Ca(2 (zeige CA2 Antikörper)+)]i are important for acquisition of luteolytic response to PGF2 alpha

  4. By regulating VEGFR2 (zeige KDR Antikörper) expression and activation, PKC-epsilon expression is critical for activation of Akt (zeige AKT1 Antikörper) and eNOS (zeige NOS3 Antikörper) by VEGF (zeige VEGFA Antikörper) and contributes to VEGF (zeige VEGFA Antikörper)-stimulated Erk (zeige MAPK1 Antikörper) activation, whereas PKC-alpha (zeige PKCa Antikörper) has opposite effects.

Rabbit Protein Kinase C, epsilon (PRKCE) Interaktionspartner

  1. Activation of PKC (zeige PKC Antikörper) induces the translocation of Nrf2 (zeige NFE2L2 Antikörper) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. in contrast to protective effects of PKC-epsilon activation in cardiomyocytes, sustained PKC-epsilon activation is detrimental to mitochondrial function and viability in renal proximal tubule cells

  3. Preferential glucose utilization by PKCepsilon hearts is orchestrated by a p-GSK3beta (zeige GSK3b Antikörper)/HIF-1alpha (zeige HIF1A Antikörper)-mediated mechanism.

PRKCE Antigen-Profil

Beschreibung des Gens

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Alternative names and synonyms associated with PRKCE

  • protein kinase C, epsilon (PRKCE) Antikörper
  • protein kinase C, epsilon a (prkcea) Antikörper
  • protein kinase C, epsilon (prkce) Antikörper
  • protein kinase C, epsilon (Prkce) Antikörper
  • 5830406C15Rik Antikörper
  • fj59b07 Antikörper
  • nPKC-epsilon Antikörper
  • pkc-epsilon Antikörper
  • Pkce Antikörper
  • PKCepsilon Antikörper
  • PKC[e] Antikörper
  • prkce Antikörper
  • PRKCH Antikörper
  • R75156 Antikörper
  • wu:fj59b07 Antikörper

Bezeichner auf Proteinebene für PRKCE

protein kinase C epsilon type , protein kinase C, epsilon , protein kinase C epsilon type-like , npkc-epsilon , pkc epsilon , nPKC-epsilon , PKC-epsilon , protein kinase C, eta

GENE ID SPEZIES
714533 Macaca mulatta
100468967 Ailuropoda melanoleuca
100005075 Danio rerio
100135720 Xenopus (Silurana) tropicalis
100440778 Pongo abelii
100543758 Meleagris gallopavo
100567346 Anolis carolinensis
100606298 Nomascus leucogenys
5581 Homo sapiens
18754 Mus musculus
29340 Rattus norvegicus
507041 Bos taurus
100009103 Oryctolagus cuniculus
449005 Sus scrofa
609934 Canis lupus familiaris
421409 Gallus gallus
101110314 Ovis aries
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