anti-Human MAP4K1 Antikörper für Enzyme Immunoassay

Recommended MAP4K1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Antikörper
  • HPK1
  • Hpk1
  • mHPK1
  • mitogen activated protein kinase kinase kinase kinase 1
  • mitogen-activated protein kinase kinase kinase kinase 1
  • Map4k1
  • MAP4K1
Epitop
C-Term
21
20
18
17
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
133
35
26
8
8
7
3
2
1
1
1
1
Wirt
Kaninchen
105
18
10
Klonalität
Polyklonal
Konjugat
Dieser MAP4K1 Antikörper ist unkonjugiert
8
8
8
7
7
7
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
73
71
33
23
19
14
10
3
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN360390
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN358384 EIA Rabbit Ig pThr165 Anmelden zum Anzeigen Polyclonal 3
1 ABIN358386 EIA Rabbit Ig pSer171 Anmelden zum Anzeigen Polyclonal 3
1 ABIN5552772 EIA WB Goat N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Antikörper
Epitop C-Term
(21), (20), (18), (17), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(133), (35), (26), (8), (8), (7), (3), (2), (1), (1), (1), (1)
Wirt Kaninchen
(105), (18), (10)
Klonalität
Polyklonal
Konjugat Dieser MAP4K1 Antikörper ist unkonjugiert
(8), (8), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(73), (71), (33), (23), (19), (14), (10), (3)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MAP4K1 Antikörper

Target Details MAP4K1 Anwendungsinformationen Handhabung Referenzen für anti-MAP4K1 Antikörper (ABIN360390) Bilder
Spezifität This antibody reacts to MAP4K1 (HPK1).
Reinigung Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human HPK1.
Isotyp Ig

Target Details MAP4K1

Produktdetails anti-MAP4K1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-MAP4K1 Antikörper (ABIN360390) Bilder zurück nach oben
Antigen
Andere Bezeichnung MAP4K1 (MAP4K1 Antibody Abstract)
Hintergrund Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: HPK1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1
Gen-ID 11184, 9606
UniProt Q92918
Forschungsgebiet Signaling
Pathways T-Zell Rezeptor Signalweg, Signaling of Hepatocyte Growth Factor Receptor

Anwendungsinformationen

Produktdetails anti-MAP4K1 Antikörper Target Details MAP4K1 Handhabung Referenzen für anti-MAP4K1 Antikörper (ABIN360390) Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MAP4K1 Antikörper Target Details MAP4K1 Anwendungsinformationen Referenzen für anti-MAP4K1 Antikörper (ABIN360390) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-MAP4K1 Antikörper (ABIN360390)

Produktdetails anti-MAP4K1 Antikörper Target Details MAP4K1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Sawasdikosol, Russo, Burakoff: "Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription." in: Blood, Vol. 101, Issue 9, pp. 3687-9, 2003

Hu, Qiu, Wang, Meyer, Tan: "Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade." in: Genes & development, Vol. 10, Issue 18, pp. 2251-64, 1996

Bilder

Produktdetails anti-MAP4K1 Antikörper Target Details MAP4K1 Anwendungsinformationen Handhabung Referenzen für anti-MAP4K1 Antikörper (ABIN360390) zurück nach oben
Bilder des Herstellers
 image for anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (C-Term) antibody (ABIN360390) anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (C-Term) antibody
 image for anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (C-Term) antibody (ABIN360390) anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (C-Term) antibody (Image 2)