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Mouse (Murine) CREB1 ELISA Kit - ABIN832415
Arora, Bhowmik, Khanam, Vohora: Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. in Behavioural brain research 2013
CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.
The sequence of the CREB gene contains a 88 bp 5 (zeige HSPD1 ELISA Kits)' UTR (zeige UTS2R ELISA Kits), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (zeige BST1 ELISA Kits)' UTR (zeige UTS2R ELISA Kits).
Data indicate increasing expression for CREB, ATF1 (zeige AFT1 ELISA Kits), and ATF3 (zeige ATF3 ELISA Kits) during gastrulation.
study concludes that miR (zeige MLXIP ELISA Kits)-132 regulated SIRT1 (zeige SIRT1 ELISA Kits)/CREB/ABCG2 (zeige ABCG2 ELISA Kits) signaling pathway contributing to the cisplatin resistance and might serve as a novel therapeutic target against gastric cancer
Leptin (zeige LEP ELISA Kits) also significantly increased cAMP levels, cAMP response element (CRE) activation, and CREB phosphorylation.
these data show the existence of functional CREB and C/EBP (zeige CEBPA ELISA Kits) binding sites in the human RIC8B gene promoter, a particular distribution of these sites and demonstrate a relevant role of CREB in stimulating transcriptional activity of this gene.
MALAT1 knockdown reduces reactive gliosis, Muller cell activation, and RGC survival in vivo and in vitro MALAT1-CREB binding maintains CREB phosphorylation by inhibiting PP2A (zeige PPP2R4 ELISA Kits)-mediated dephosphorylation, which leads to continuous CREB signaling activation.
aberrant activation of CREB-C/EBPdelta (zeige CEBPD ELISA Kits) axis concurring to AML (zeige RUNX1 ELISA Kits) onset by disrupting the myeloid cell differentiation process
miR (zeige MLXIP ELISA Kits)-27b-3p levels were found to be significantly negatively correlated with both NR5A2 (zeige NR5A2 ELISA Kits) and CREB1 levels in breast cancer tissues.
Interactions between GNB3 (zeige GNB3 ELISA Kits), CREB1 and negative life events were revealed. Further evidence is provided about the role of the environment in genetic vulnerability to major depression.
UCA1 promotes cisplatin/gemcitabine resistance in bladder cancer cells through CREB modulation of miR (zeige MLXIP ELISA Kits)-196a-5p expression.
Report a distinct group of myxoid mesenchymal neoplasms occurring in children or young adults with a predilection for intracranial locations with EWSR1 (zeige EWSR1 ELISA Kits)-AFT1/CREB1/CREM (zeige CREM ELISA Kits) fusions.
CREB1/FoxA1 (zeige FOXA1 ELISA Kits) signaling is a targetable driver of prostate cancer progression and serves as a biomarker of poor clinical outcomes.
PGE2 serves as a central regulator of the Ren (zeige REN1 ELISA Kits)-1c gene in the principal cells of the kidney collecting ducts via the PKC (zeige PKC ELISA Kits)/cAMP/CREB pathway.
study revealed the involvement of CREB in B-1a cells, which was upregulated to increase the production of IL-10 (zeige IL10 ELISA Kits) for attenuating inflammation and organ injury, and finally improving survival during sepsis
In conclusion, glucocorticoid couples mGR (zeige GRHL1 ELISA Kits) with Galphas (zeige GNAS ELISA Kits) and triggers cAMP-PKA-CREB axis dependent on the lipid raft to stimulate BACE1 (zeige BACE ELISA Kits) upregulation and Abeta (zeige APP ELISA Kits) generation.SIGNIFICANCE STATEMENT Patients with Alzheimer's disease (AD) have been growing sharply and stress is considered as the major environment factor of AD.
CREB was found to bind to GSK3beta (zeige GSK3b ELISA Kits) promoter and essential for cAMP-mediated regulation of GSK3beta (zeige GSK3b ELISA Kits).
The NR2B (zeige GRIN2B ELISA Kits)-CREB-miR212/132-CRTC1 (zeige CRTC1 ELISA Kits)-CREB signal network plays an important role in the regulation of pain.
Therefore, our study suggests that CREB and PSD95 are novel substrates of PERK, so inhibition of PERK phosphorylation using GSK2656157 would be beneficial against memory impairment after TBI.
Our results elucidate the specific role of the transcription factors CREB, SRF, and MEF2 (zeige MEF2C ELISA Kits) in the depression and potentiation components of ODP in vivo, therefore better informing future attempts to find therapeutic targets for diseases where activity-dependent plasticity is disrupted.
neuronal activity promotes CREB-dependent transcription by increasing the frequency of CREB binding to highly localized genome locations
Expression of miR (zeige MLXIP ELISA Kits)-26a or knockdown of Klf4 (zeige KLF4 ELISA Kits) or Creb or C/ebpbeta (zeige CEBPB ELISA Kits), attenuated the survival of Mycobacterium tuberculosis in macrophages.
The findings indicate that the activation of sigma1R (zeige SIGMAR1 ELISA Kits) can alleviate postpartum "depression" through increasing nNOS (zeige NOS1 ELISA Kits)-NO-CREB activities.
The expression of porcine Prdx6 (zeige PRDX6 ELISA Kits) gene is up-regulated by C/EBPbeta (zeige CEBPB ELISA Kits) and CREB.
Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.
Data indicate that Ser738/742-to-glutamate (zeige GRIN2A ELISA Kits) protein kinase D (zeige PRKD1 ELISA Kits) mutant increased AngII-induced CREB protein and activating transcription factor 2 (zeige ATF2 ELISA Kits) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (zeige STAR ELISA Kits) promoter.
SUMO-1 (zeige SUMO1 ELISA Kits) has a role in modifying cAMP-response element-binding protein CREB (zeige CREB ELISA Kits) in prolonged hypoxia.
dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (zeige LYPLA1 ELISA Kits)
the p38-MAPK (zeige MAPK14 ELISA Kits)/CREB pathway plays a critical role in TNFalpha (zeige TNF ELISA Kits)-induced VCAM-1 (zeige VCAM1 ELISA Kits) expression
We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements
p38 MAPK (zeige MAPK14 ELISA Kits) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (zeige MAPK14 ELISA Kits) pathway mediates the phosphorylation of CREB.
modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
cAMP responsive element binding protein 1
, cAMP responsive element binding protein
, cyclic AMP-responsive element-binding protein 1
, active transcription factor CREB
, cAMP-response element-binding protein-1
, cAMP-responsive element-binding protein 1
, transactivator protein
, Y protein
, cAMP response element binding protein 1
, cAMP response element-binding protein
, cyclic AMP-responsive element binding protein, delta
, cyclic AMP-responsive DNA-binding protein