anti-Non-Human Primate CD28 Antikörper für Immunoprecipitation

Recommended CD28 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD28 Antikörper
  • Tp44
  • CD28RNA
  • CD28 molecule
  • CD28 antigen
  • Cd28 molecule
  • CD28
  • Cd28
Reaktivität
Human, Non-Human Primate
471
388
102
70
51
34
27
26
25
22
15
5
3
3
3
2
1
1
1
Wirt
Maus
503
193
91
70
40
27
12
1
Klonalität
Monoklonal
Konjugat
Dieser CD28 Antikörper ist unkonjugiert
110
93
72
36
20
19
18
18
17
16
16
12
12
12
12
11
10
10
8
7
6
6
6
6
6
5
4
3
3
2
2
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
752
207
184
146
141
137
128
127
87
72
26
13
13
9
8
5
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN638435
198,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN775705 FACS Func ICC IHC (f) IP WB Mouse IgG1 Anmelden zum Anzeigen CD28-2 5
1 ABIN457388 FACS Func ICC IHC (f) IP WB PerCP Mouse IgG1 Anmelden zum Anzeigen CD28-2 6
1 ABIN349705 FACS Func ICC IHC (f) IP WB APC Mouse IgG1 Anmelden zum Anzeigen CD28-2 6
1 ABIN349707 FACS Func ICC IHC (f) IP WB FITC Mouse IgG1 Anmelden zum Anzeigen CD28-2 4
1 ABIN349710 FACS Func ICC IHC (f) IP WB PE Mouse IgG1 Anmelden zum Anzeigen CD28-2 6

anti-CD28 Antikörper für Immunoprecipitation mit den meisten Publikationen

Ähnliche anti-CD28 Antikörper

Applikation / Reaktivität Non-Human Primate Human
Flow Cytometry (FACS) 6 Antikörper 346 Antikörper
Functional Studies (Func) 6 Antikörper 48 Antikörper
Immunocytochemistry (ICC) 6 Antikörper 108 Antikörper
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 6 Antikörper
Immunoprecipitation (IP) 6 Antikörper
Western Blotting (WB) 6 Antikörper
Activation (Act) 1 Antikörper
Agonist (Agon) 3 Antikörper
Biochemical Assay (BCA) 3 Antikörper
Cell Culture (CC) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 10 Antikörper
ELISA 122 Antikörper
ELISA (Detection) 1 Antikörper
Enzyme Immunoassay (EIA) 1 Antikörper

General

Antigen CD28 Antikörper
Reaktivität Human, Non-Human Primate
(471), (388), (102), (70), (51), (34), (27), (26), (25), (22), (15), (5), (3), (3), (3), (2), (1), (1), (1)
Wirt Maus
(503), (193), (91), (70), (40), (27), (12), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD28 Antikörper ist unkonjugiert
(110), (93), (72), (36), (20), (19), (18), (18), (17), (16), (16), (12), (12), (12), (12), (11), (10), (10), (8), (7), (6), (6), (6), (6), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
(752), (207), (184), (146), (141), (137), (128), (127), (87), (72), (26), (13), (13), (9), (8), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD28 Antikörper

Target Details CD28 Anwendungsinformationen Handhabung ProductDetails: References for anti-CD28 antibody (ABIN638435) Bilder
Spezifität The antibody CD28.2 reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
HLDA V., WS Code 5T CD28.05
Reinigung Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Reinheit > 95 % (by SDS-PAGE)
Sterilität 0.2 μm filtered
Endotoxin-Niveau Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Immunogen DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA
Klon CD28-2
Isotyp IgG1

Target Details CD28

Produktdetails anti-CD28 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-CD28 antibody (ABIN638435) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD28 (CD28 Antibody Abstract)
Hintergrund CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Gen-ID 940
Forschungsgebiet Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis
Pathways T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-CD28 Antikörper Target Details CD28 Handhabung ProductDetails: References for anti-CD28 antibody (ABIN638435) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD28 Antikörper Target Details CD28 Anwendungsinformationen ProductDetails: References for anti-CD28 antibody (ABIN638435) Bilder zurück nach oben
Konzentration 1 mg/mL
Buffer Azide free phosphate buffered saline (PBS), approx. pH 7.4.
Handhabung Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

ProductDetails: References for anti-CD28 antibody (ABIN638435)

Produktdetails anti-CD28 Antikörper Target Details CD28 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Scharschmidt, Wegener, Heissmeyer, Rao, Krappmann: "Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling." in: Molecular and cellular biology, Vol. 24, Issue 9, pp. 3860-73, 2004

Jeong, Qiao, Nascimbeni, Hu, Rehermann, Murthy, Liang: "Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates." in: Journal of virology, Vol. 78, Issue 13, pp. 6995-7003, 2004

Marti, Krause, Post, Lyddane, Dupont, Sadelain, King: "Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 197-206, 2001

Galea-Lauri, Darling, Gan, Krivochtchapov, Kuiper, Gäken, Souberbielle, Farzaneh: "Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 1, pp. 62-70, 1999

Tazi, Moreau, Bergeron, Dominique, Hance, Soler: "Evidence that Langerhans cells in adult pulmonary Langerhans cell histiocytosis are mature dendritic cells: importance of the cytokine microenvironment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3511-5, 1999

Nunes, Klasen, Franco, Lipcey, Mawas, Bagnasco, Olive: "Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity." in: The Biochemical journal, Vol. 293 ( Pt 3), pp. 835-42, 1993

Allgemeine Veröffentlichungen

Nunès, Klasen, Ragueneau, Pavon, Couez, Mawas, Bagnasco, Olive: "CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events." in: International immunology, Vol. 5, Issue 3, pp. 311-5, 1993

Bilder

Produktdetails anti-CD28 Antikörper Target Details CD28 Anwendungsinformationen Handhabung ProductDetails: References for anti-CD28 antibody (ABIN638435) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD28 Antikörper (CD28) (ABIN638435) Surface staining of human peripheral blood leukocytes with anti-human CD28 (CD28.2) p...