Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Proteine (CASK)

Bezeichnung:
Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Proteine (CASK)
Auf www.antikoerper-online.de finden Sie aktuell 9 Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Antikörper (78) und Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 101 Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Produkte verfügbar.
Synonyme:
CAGH39, caki, camguk, Cask, CG6703, CG13412, CG13413, cmg, CMG/CASK, dCASK, DLin-2, Dmel\\CG6703, DXPri1, DXRib1, FGS4, LIN-2, LIN2, MICPCH, mLin-2, MRXSNA, Pals3, RE09582p, TNRC8, wu:fb70g06
alle Proteine anzeigen Gen GeneID UniProt
CASK 8573 O14936
CASK 12361 O70589
Ratte CASK CASK 29647 Q62915

Weitere Synonyme anzeigen

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Am meisten referenzierte Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Proteine

  1. Human CASK Protein expressed in Baculovirus infected Insect Cells - ABIN2004883 : Mukherjee, Sharma, Urlaub, Bourenkov, Jahn, Südhof, Wahl: CASK Functions as a Mg2+-independent neurexin kinase. in Cell 2008 (PubMed)
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Weitere Proteine zu Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Interaktionspartner

  1. Data show that Drosophila CASK is associated with both pre and postsynaptic membranes, and that loss of presynaptic CASK leads to less evoked synaptic transmission, fewer spontaneous synaptic events, and reduced synaptic vesicle cycling.

  2. Full-length CASK-beta appears to have a unique role within central circuits that control motor output

  3. Camguk localizes to synaptic regions of the brain and associates in an ATP-regulated manner with CaMKII to catalyze formation of a pool of calcium-insensitive CaMKII.

  4. The results of this study support the involvement of CAKI in neurotransmitter release and nervous system function.

  5. the Drosophila homolog of CASK/Camguk can act as a gain controller on the transition to calcium-independence in vivo.

  6. Dneurexin (DNRX (zeige NRXN1 Proteine)) is important for locomotion through a genetic interaction with the scaffold protein (zeige HOMER1 Proteine), CAKI/CMG, the Drosophila homolog of vertebrate CASK.

Human Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Interaktionspartner

  1. During atrial dilation/remodeling, CASK expression was reduced but its localization remained unchanged.

  2. we report a patient presenting with a complex phenotype consisting of severe, adult-onset, dilated cardiomyopathy, hearing loss and developmental delay, in which exome sequencing revealed two genetic variants that are inherited from a healthy mother: a novel missense variant in the CASK gene, mutations in which cause a spectrum of neurocognitive manifestations

  3. In clinical specimens, CASK was over-expressed in tumors and H. pylori positive tissues, and its mRNA levels were inversely correlated with miR (zeige MLXIP Proteine)-203 expression.

  4. Data indicate that patients with low calcium/calmodulin-dependent serine protein kinase (CASK) staining had a significantly better survival compared to patients with high CASK staining.

  5. The findings suggest that CASK and the truncated prestin (zeige SLC26A5 Proteine) splice isoform contribute to confinement of prestin (zeige SLC26A5 Proteine) to the basolateral region of the plasma membrane.

  6. CASK regulates CaMKII (zeige CAMK2G Proteine) autophosphorylation in a pathway required for memory formation.

  7. a model whereby CASK recruits FRMD7 (zeige FRMD7 Proteine) to the plasma membrane to promote neurite outgrowth during development of the oculomotor neural network and that defects in this interaction result in nystagmus.

  8. our findings suggest a molecular mechanism by which CASK binding regulates SAP97 (zeige DLG1 Proteine) conformation and its subsequent sorting and synaptic targeting of AMPARs and NMDARs during trafficking to synapses.

  9. CASK represents an intracellular gateway to regulate purinergic nociceptive signaling.

  10. An early diagnosis and be useful for medical care of females with ID and MICPCH associated with CASK mutations.

Mouse (Murine) Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Interaktionspartner

  1. CASK phosphorylates neurexin, modulating the interaction of liprin-alpha with the CASK-neurexin1beta-Mint1 complex.

  2. Ths data of this study implies that some phenotypic components of CASK heterozygous deletion mutation associated disorders represent systemic manifestation of metabolic stress.

  3. The findings suggest that CASK and the truncated prestin (zeige SLC26A5 Proteine) splice isoform contribute to confinement of prestin (zeige SLC26A5 Proteine) to the basolateral region of the plasma membrane.

  4. DLG1 (zeige DLG1 Proteine) and CASK play critical cooperative roles in maintaining the nephron progenitor population, potentially via a mechanism involving effects on FGF signaling

  5. Immunofluorescence shows colocalization of Cx43 (zeige GJA1 Proteine) and CASK in brain astrocytes.

  6. CASK negatively regulates PMCA4b (zeige ATP2B4 Proteine) by directly binding to it and JAM-A (zeige F11R Proteine) positively regulates it indirectly through CASK

  7. Data show that CASK expression and the appropriate localization of DLG1 and LIN7c are not essential for either epithelial polarity or intestinal homeostasis in vivo.

  8. Post-translational modifications to CASK are major regulatory steps leading to its proteasomal degradation.

  9. CASK is transcribed in mouse testis and processing may play a role in the acquisition of spserm and sperm functions.

  10. CASK and Dlg (zeige DLG4 Proteine) may act as a scaffold for organizing receptors and channels at the postsynaptic membrane of the neuromuscular junction.

Cow (Bovine) Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Interaktionspartner

  1. findings suggest that Cask plays an important role in all retinal synapses

Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) Protein Überblick

Protein Überblick

This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK)

  • CASK ortholog (CASK)
  • Peripheral plasma membrane protein CASK (Bm1_33725)
  • peripheral plasma membrane protein CASK (LOAG_08350)
  • peripheral plasma membrane protein CASK (Tsp_03763)
  • calcium/calmodulin-dependent serine protein kinase b (caskb)
  • calcium/calmodulin-dependent serine protein kinase (cask)
  • calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK)
  • calcium/calmodulin-dependent serine protein kinase (MAGUK family) (Cask)
  • calcium/calmodulin-dependent serine protein kinase (MAGUK family) (cask)
  • CAGH39 Protein
  • caki Protein
  • camguk Protein
  • Cask Protein
  • CG6703 Protein
  • CG13412 Protein
  • CG13413 Protein
  • cmg Protein
  • CMG/CASK Protein
  • dCASK Protein
  • DLin-2 Protein
  • Dmel\\CG6703 Protein
  • DXPri1 Protein
  • DXRib1 Protein
  • FGS4 Protein
  • LIN-2 Protein
  • LIN2 Protein
  • MICPCH Protein
  • mLin-2 Protein
  • MRXSNA Protein
  • Pals3 Protein
  • RE09582p Protein
  • TNRC8 Protein
  • wu:fb70g06 Protein

Bezeichner auf Proteinebene für CASK

CASK-PA , CASK-PB , CASK-PD , CASK-PE , CASK-PF , CASK-PG , CASK-PH , CG6703-PA , CG6703-PB , CG6703-PD , CG6703-PE , CG6703-PF , CG6703-PG , CG6703-PH , Calcium/calmodulin-dependent protein kinase , Camguk/CASK adaptor protein , calmodulin-dependent kinase , camguk , Peripheral plasma membrane protein CASK , peripheral plasma membrane protein CASK , calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase , hCASK , protein lin-2 homolog , trinucleotide repeat containing 8 , G-protein-coupled receptor GPR34

GENE ID SPEZIES
42567 Drosophila melanogaster
6101633 Brugia malayi
9945779 Loa loa
10910490 Trichinella spiralis
100148073 Danio rerio
259195 Danio rerio
8573 Homo sapiens
12361 Mus musculus
29647 Rattus norvegicus
480887 Canis lupus familiaris
446996 Xenopus laevis
404149 Bos taurus
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