anti-CADPS2 (CADPS2) Antikörper

Bezeichnung:
anti-Ca++-Dependent Secretion Activator 2 Antikörper (CADPS2)
Auf www.antikoerper-online.de finden Sie aktuell 18 Ca++-Dependent Secretion Activator 2 (CADPS2) Antikörper von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CADPS2 Proteine (3) und CADPS2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 23 CADPS2 Produkte verfügbar.
Synonyme:
A230044C21Rik, Caps, Caps-2, Caps1, Caps2, Cpd2, RGD1559440

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anti-Rat (Rattus) CADPS2 Antikörper:

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anti-Mouse (Murine) CADPS2 Antikörper:

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Am meisten referenzierte anti-CADPS2 Antikörper

  1. Human Polyclonal CADPS2 Primary Antibody für IHC, ELISA - ABIN1001982 : Sadakata, Washida, Furuichi: Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants. in BMC neuroscience 2007 (PubMed)
    Zeige alle 3 Referenzen für 1001982

Weitere Antikörper gegen CADPS2 Interaktionspartner

Human Ca++-Dependent Secretion Activator 2 (CADPS2) Interaktionspartner

  1. These results indicate that LRRK2 (zeige LRRK2 Antikörper) and alpha-synuclein (zeige SNCA Antikörper) participate in the dysregulation of CADPS2 by altering transcription and support the hypothesis that synaptic dysfunctions, through different mechanisms, might contribute to the neuronal defects of diseases such as Parkinson's disease.

  2. Mutation screening of 187 patients with autism spectrum disorders and 36 with intellectual disability identified a missense change of maternal origin disrupting CADPS2/D2DR (zeige DRD2 Antikörper) interaction.

  3. We speculate that haploinsufficiency of CADPS2 contributes to ASDs.

  4. identification, cloning, and comparative characterization of a second mammalian CAPS (zeige CAPS Antikörper) isoform, CAPS2 (zeige CAPS2 Antikörper); concluded that at the functional level, CAPS2 (zeige CAPS2 Antikörper) is largely redundant with CAPS1 (zeige CAPS Antikörper)

  5. Results from Cadps2-deficient mice and human data suggest that a disturbance in CADPS2-mediated neurotrophin release contributes to autistic-like cellular and behavioral phenotypes.

  6. CAPS (zeige CAPS Antikörper) proteins are involved in optimizing vesicular monoamine uptake and storage mediated by VMAT1 (zeige SLC18A1 Antikörper) and VMAT2 (zeige Slc18a2 Antikörper)

Mouse (Murine) Ca++-Dependent Secretion Activator 2 (CADPS2) Interaktionspartner

  1. CAPS2 plays an important role in subcellular locality (axonal vs. somato (zeige SSTR5 Antikörper)-dendritic) of enhanced BDNF (zeige BDNF Antikörper) and NT-3 (zeige NTF3 Antikörper) release, which is indispensable for proper development of postnatal cerebellum.

  2. Data suggest that adequate levels of CAPS2 are critical for normal brain development and normal behavior; allelic changes due to copy number variation may contribute to autistic behavior.

  3. Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF (zeige BDNF Antikörper) and causes autistic-like behavior in mice

  4. identification, cloning, and comparative characterization of a second mammalian CAPS (zeige CAPS Antikörper) isoform, CAPS2; concluded that at the functional level, CAPS2 is largely redundant with CAPS1 (zeige CAPS Antikörper)

  5. results suggest that CAPS2 mediates the depolarization-dependent release of NT-3 (zeige NTF3 Antikörper) and BDNF (zeige BDNF Antikörper) from granule cells, leading to regulation in cell differentiation and survival during cerebellar development

  6. CADPS2-KO mice show autistic-like phenotypes. Moreover, the results show that some autistic patients have an aberrant splicing variant of CADPS2 mRNA, suggesting that a disturbance in CADPS2-mediated neurotrophin (zeige BDNF Antikörper) release contributes to autism.

  7. CADPS2/CAPS2-knockout mice exhibit pronounced impairments in cerebellar development and functions. These results are also suggestive of an involvement of the CADPS2/CAPS2 gene, which is located within the AUTS1, in the cerebellar deficits of autism.

  8. The results show the immunohistochemical localization of the CAPS (zeige CAPS Antikörper) family proteins in various mouse tissues.

  9. The two CAPS (zeige CAPS Antikörper) family proteins are complementarily distributed throughout the various brain regions of mice.

CADPS2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CADPS2

  • Ca++-dependent secretion activator 2 (CADPS2) Antikörper
  • Ca++-dependent secretion activator (Cadps) Antikörper
  • Ca++-dependent secretion activator 2 (Cadps2) Antikörper
  • Ca2+-dependent activator protein for secretion 2 (Cadps2) Antikörper
  • A230044C21Rik Antikörper
  • Caps Antikörper
  • Caps-2 Antikörper
  • Caps1 Antikörper
  • Caps2 Antikörper
  • Cpd2 Antikörper
  • RGD1559440 Antikörper

Bezeichner auf Proteinebene für CADPS2

Ca2+-dependent activator protein for secretion 2 , Ca++-dependent secretion activator 2 , CAPS-1 , Ca2+-dependent activator protein , Ca2+-dependent secretion activator , Ca<2+-dependent activator protein for secretion , calcium-dependent activator protein for secretion 1 , calcium-dependent secretion activator 1 , rCAPS , CAPS-2 , calcium-dependent activator protein for secretion 2 , calcium-dependent secretion activator 2 , cerebellum postnatal development associated protein 2

GENE ID SPEZIES
100056300 Equus caballus
472494 Pan troglodytes
26989 Rattus norvegicus
93664 Homo sapiens
312166 Rattus norvegicus
475304 Canis lupus familiaris
100525671 Sus scrofa
519444 Bos taurus
320405 Mus musculus
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