Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
We show that Arf6 functions in the adult nervous system to control ethanol-induced behavior.
Cindr-mediated regulation of Arf6 is a widely used mechanism in emerging epithelia.
ARF6 promotes rapid recycling of endosomal membrane stores during spermatocyte cytokinesis, which is critical for rapid cleavage furrow ingression.
This study identifies a novel regulatory crosstalk between Ral (zeige rala ELISA Kits) and Arf6 that controls Ral (zeige rala ELISA Kits) function in cells.
ARHGAP24 (zeige ARHGAP24 ELISA Kits) may regulate pseudopod formation downstream of activated ARF6 in MDA-MB-231 human breast carcinoma cells.
ARF6 was a downstream target of Kras/ERK (zeige EPHB2 ELISA Kits) signaling pathway, and the strong correlation of expression between Kras and ARF6 in the TCGA dataset further confirmed this observation.
FRMD4A RNAi or inhibition of cytohesins strongly upregulated secretion of endogenous tau. These results suggest that FRMD4A, a genetic risk factor for late-onset Alzheimer's disease, regulates tau secretion by activating cytohesin-Arf6 signaling.
Macrophage tissue factor (zeige F3 ELISA Kits) prothrombotic activity is regulated by integrin-alpha4/arf6 trafficking.
Here the authors report that EspG interacts specifically with the small GTPases ARF6 and Rab35 (zeige RAB35 ELISA Kits) during infection.
These results identify RalF as the first bacterial effector to directly activate Arf6, a process that initiates alterations in phosphoinositol metabolism critical for a lineage-specific Rickettsia entry mechanism.
Data suggest that activated ARF6 controls GNAQ (zeige GNAQ ELISA Kits) and b-catenin signaling by regulating protein trafficking between intracellular compartments. Blocking ARF6 with a small-molecule inhibitor reduces uveal melanoma cell proliferation and tumorigenesis in a mouse model.
expression and activation of LHCGR (zeige LHCGR ELISA Kits) and ARF6 are up-regulated in GC from PCOS women but the mechanism of agonist-induced LHCGR (zeige LHCGR ELISA Kits) internalization is unaltered
The Squamous cell carcinoma of the tongue cell line SCC (zeige CYP11A1 ELISA Kits)-9, which overexpress Arf6 and AMAP1 (zeige ASAP1 ELISA Kits), also expressed EPB41L5 (zeige EPB41L5 ELISA Kits) at high levels to promote invasiveness, whereas the weakly invasive SCC (zeige CYP11A1 ELISA Kits)-25 cells did not express EPB41L5 (zeige EPB41L5 ELISA Kits) at notable levels.
The present study demonstrated that the Arf6-specific GAP ACAP3 (zeige Acap3 ELISA Kits) plays a crucial role in neuronal migration through regulating morphological changes of neurons at intermediate zone of developing cerebral cortex.
Study demonstrates that Arf6 regulates neuronal migration in the intermediate zone through the FIP3 (zeige IKBKG ELISA Kits)-dependent trafficking of endosomes containing N-cadherin (zeige CDH2 ELISA Kits) during cortical layer formation.
The results show that ARNO (zeige CYTH2 ELISA Kits) interaction with the RLIP76 (zeige RALBP1 ELISA Kits) N-terminus regulates cell spreading and motility via PI3K and Arf6, independent of RLIP76 (zeige RALBP1 ELISA Kits) control of Rac (zeige AKT1 ELISA Kits).
The present study provided evidence that BRAG2a is a novel component of the photoreceptor dystrophin (zeige DMD ELISA Kits)-associated glycoprotein complex (DGC (zeige GGCX ELISA Kits)), suggesting functional involvement of the BRAG2a-Arf6 pathway downstream of the DGC (zeige GGCX ELISA Kits).
cycling between active and inactive forms of Arf6, which is precisely regulated by ACAP3 (zeige Acap3 ELISA Kits) in concert with a guanine-nucleotide-exchange factor (zeige ARHGEF12 ELISA Kits)(s), seems to be required for neurite outgrowth of hippocampal neurons
ARF6-dependent pathway is the predominant route responsible for the ABCA1 (zeige ABCA1 ELISA Kits) internalization and degradation, whereas ARF6-independent endocytic pathways may contribute to ABCA1 (zeige ABCA1 ELISA Kits) recycling and efflux of intracellular cholesterol.
These findings suggest that SDCCAG3 (zeige SDCCAG3 ELISA Kits) might function in endosomal trafficking downstream of Arf6.
both Arf6 activation through GluN2B (zeige GRIN2B ELISA Kits)-BRAG1 (zeige IQSEC2 ELISA Kits) during early development and the transition from BRAG1 (zeige IQSEC2 ELISA Kits)- to BRAG2-dependent Arf6 signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses.
Pparg pathway acts on cephalic neural crest to direct adipocyte differentiation at the expense of osteoblast formation
PPAR (zeige PPARA ELISA Kits) expression, the activity of its target gene AOX (zeige ACOX1 ELISA Kits), and peroxisomal biogenesis are developmentally modulated in zebrafish
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
ADP ribosylation factor III
, ADP-ribosylation factor 6
, peroxisome proliferator-activated receptor gamma