anti-Kaninchen CYP1B1 Antikörper für Western Blotting

Recommended CYP1B1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Antikörper
  • CYP1B1
  • CP1B
  • CYPIB1
  • GLC3A
  • P4501B1
  • P4501b1
  • CYP1B
  • zgc:136223
  • cytochrome P450 1B1
  • cytochrome P450, family 1, subfamily B, polypeptide 1
  • cytochrome P450 family 1 subfamily B member 1
  • cytochrome P450 family 1 subfamily C polypeptide 1
  • cytochrome P450, family 1, subfamily b, polypeptide 1
  • CYP1B1
  • LOC100719054
  • CYP1C1
  • Cyp1b1
  • cyp1b1
Epitop
Middle Region
15
7
6
5
5
5
5
4
3
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
121
83
80
5
4
3
3
2
2
2
2
1
1
1
1
1
1
Wirt
Kaninchen
81
42
Klonalität
Polyklonal
Konjugat
Dieser CYP1B1 Antikörper ist unkonjugiert
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
99
59
52
14
13
3
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN2784612
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0849469 ABIN2784613 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN321883 WB Rabbit IgG AA 200-249 Anmelden zum Anzeigen Polyclonal

General

Antigen Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Antikörper
Epitop Middle Region
(15), (7), (6), (5), (5), (5), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(121), (83), (80), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(81), (42)
Klonalität
Polyklonal
Konjugat Dieser CYP1B1 Antikörper ist unkonjugiert
(5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(99), (59), (52), (14), (13), (3), (2), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CYP1B1 Antikörper

Target Details CYP1B1 Anwendungsinformationen Handhabung Referenzen für anti-CYP1B1 Antikörper (ABIN2784612) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975517.
Sequenz AVANVMSAVC FGCRYSHDDP EFRELLSHNE EFGRTVGAGS LVDVMPWLQY
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against CYP1B1. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CYP1B1

Target Details CYP1B1

Produktdetails anti-CYP1B1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CYP1B1 Antikörper (ABIN2784612) Bilder zurück nach oben
Antigen
Andere Bezeichnung CYP1B1 (CYP1B1 Antibody Abstract)
Hintergrund CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CP1B, GLC3A, P4501B1, CYPIB1
Protein Interaction Partner: UBC, SAE1,
Protein Size: 543
Molekulargewicht 61 kDa
Gen-ID 1545
NCBI Accession NM_000104, NP_000095
UniProt Q16678
Forschungsgebiet Signaling, Metabolism
Pathways Steroid Hormone Biosynthesis

Anwendungsinformationen

Produktdetails anti-CYP1B1 Antikörper Target Details CYP1B1 Handhabung Referenzen für anti-CYP1B1 Antikörper (ABIN2784612) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 543 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CYP1B1 Antikörper Target Details CYP1B1 Anwendungsinformationen Referenzen für anti-CYP1B1 Antikörper (ABIN2784612) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CYP1B1 Antikörper (ABIN2784612)

Produktdetails anti-CYP1B1 Antikörper Target Details CYP1B1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Staršíchová, Hrubá, Slabáková, Pernicová, Procházková, P?n?íková, Seda, Kabátková, Vondrá?ek, Kozubík, Machala, Sou?ek: "TGF-?1 signaling plays a dominant role in the crosstalk between TGF-?1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells." in: Cellular signalling, Vol. 24, Issue 8, pp. 1665-76, 2012

Wang, Hawkins, Miller: "Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 2, pp. 644-52, 2011

Bilder

Produktdetails anti-CYP1B1 Antikörper Target Details CYP1B1 Anwendungsinformationen Handhabung Referenzen für anti-CYP1B1 Antikörper (ABIN2784612) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (Middle Region) antibody (ABIN2784612) Lanes: Lane 1: Human lung microsome lysate Lane 2-5: 150 ug mouse lung microsome lys...
Western Blotting (WB) image for anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (Middle Region) antibody (ABIN2784612) WB Suggested Anti-CYP1B1 Antibody Titration: 0.2-1 ug/ml Positive Control: Human Liver