Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteine (TFAP2C)

Bezeichnung:
Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteine (TFAP2C)
Auf www.antikoerper-online.de finden Sie aktuell 6 Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Antikörper (110) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 124 Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Produkte verfügbar.
Synonyme:
AA409384, Ap-2.2, ap-2g, AP2-GAMMA, AP2gamma, ERF1, hAP-2g, Stra2, Tcfap2c, tfa2pc, TFAP2C, TFAP2G, tfap2gamma, wu:fb48g05, wu:fb49c04, zgc:92088
alle Proteine anzeigen Gen GeneID UniProt
Ratte TFAP2C TFAP2C 362280  
TFAP2C 7022 Q92754
TFAP2C 21420 Q61312

Weitere Synonyme anzeigen

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Am meisten referenzierte Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteine

  1. Human TFAP2C Protein expressed in Escherichia coli (E. coli) - ABIN2005457 : Woodfield, Hitchler, Chen, Domann, Weigel: Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)
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Weitere Proteine zu Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Interaktionspartnern

Human Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaktionspartner

  1. miR (zeige MLXIP Proteine)-137 is a Slug (zeige SNAI2 Proteine)-induced miRNA that relays the pro-metastatic effects of Slug (zeige SNAI2 Proteine) by targeting TFAP2C in non-small cell lung cancer cells.

  2. TFAP2C might increase oncogenic miR (zeige MLXIP Proteine)-183 expression and consequently downregulate tumor-suppressive AKAP12 and decrease tumor-suppressive miR (zeige MLXIP Proteine)-33a expression and subsequently induce CDK6 (zeige CDK6 Proteine) in NSCLC cells.

  3. Higher TFAP2C protein expression correlates with poor overall survival after 10 years of diagnosis in ERalpha (zeige ESR1 Proteine)-positive breast cancer.

  4. TFAP2C has an important role in regulated luminal-specific genes and may be a viable therapeutic target in breast cancer.

  5. ShRNA knockdown of AP-2gamma in neuroblastoma (zeige ARHGEF16 Proteine) cells results in significant inhibit of cell proliferation.

  6. Knockdown of TFAP2C or RET (zeige RET Proteine) inhibited activation of ERK (zeige EPHB2 Proteine) and AKT (zeige AKT1 Proteine) in MCF-7 cells. Knockdown of TFAP2C, which controls ER (estrogen receptor (zeige ESR1 Proteine)) and RET (zeige RET Proteine), had a greater effect on cell growth than either RET (zeige RET Proteine) or ER alone.

  7. role for TFAP2C in melanoma via its regulation of ECM1 (zeige ECM1 Proteine)

  8. TFAP2C amplification and overexpression represents a genetic dependency in ERBB2 (zeige ERBB2 Proteine)+ve breast cancer.

  9. TFAP2C regulates expression of the RET proto-oncogene (zeige RET Proteine) through five AP-2 (zeige GTF3A Proteine) regulatory sites in the RET (zeige RET Proteine) promoter.

  10. Results demonstrate that TFAP2C regulates the expression of GPX1 (zeige GPX1 Proteine), which influences the redox state and sensitivity to oxidative stress induced (zeige SQSTM1 Proteine) by peroxides.

Zebrafish Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaktionspartner

  1. Redundant activities of Tfap2a (zeige TFAP2A Proteine) and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos.

Xenopus laevis Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaktionspartner

  1. Expression of TFAP2beta (zeige TFAP2B Proteine) and TFAP2gamma genes in Xenopus laevis.

Cow (Bovine) Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaktionspartner

  1. Tfap2c expression is altered in early preimplantation SCNT embryos, which may have developmental consequences resulting from genes influenced by Tfap2c, but expression was not different at the blastocyst stage and in placentomes.

Mouse (Murine) Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaktionspartner

  1. TFAP2C in trophoblasts controls proliferation by repressing Cdkn1a (zeige CDKN1A Proteine) and activating the MAPK (zeige MAPK1 Proteine) pathway, further supporting differentiation of glycogen (zeige GYS1 Proteine) cells by activating the AKT (zeige AKT1 Proteine) pathway

  2. these findings indicate that a reduction in the gene dosage of placental Tfap2c leads to morphological changes in the labyrinth at midgestation

  3. TFAP2C regulates tumorigenesis, cell growth and survival in HER2 (zeige ERBB2 Proteine)-amplified breast cancer through transcriptional regulation of EGFR (zeige EGFR Proteine).

  4. Transcription factor AP-2gamma induces early Cdx2 (zeige CDX2 Proteine) expression and represses HIPPO signaling to specify the trophectoderm lineage.

  5. we characterize the cis (zeige CISH Proteine)-regulatory organization of a large genomic locus consisting of Tfap2c and Bmp7 (zeige BMP7 Proteine). We show that this locus is structurally partitioned into two distinct domains by the constitutive action of a discrete transition zone

  6. mice with a heterozygous deletion of the TFAP2C target gene Nanos3 (zeige NANOS3 Proteine) are also prone to develop teratomas. These data highlight TFAP2C as a critical and dose-sensitive regulator of germ cell fate.

  7. Tcfap2c is not required for Oct4 (zeige POU5F1 Proteine) silencing in mouse blastocysts, but may be necessary for the maintenance of Oct4 (zeige POU5F1 Proteine) expression during the 8 cell-to-morula transition.

  8. critical roles for AP-2 (zeige TFAP2A Proteine) activity in retinogenesis, delineating the overlapping expression patterns of Tcfap2a (zeige TFAP2A Proteine), Tcfap2b (zeige TFAP2B Proteine), and Tcfap2c in the neural retina, and revealing a redundant requirement for Tcfap2a (zeige TFAP2A Proteine) and Tcfap2b (zeige TFAP2B Proteine) in horizontal and amacrine cell development

  9. An important role for TCFAP2C, SMARCA4 (zeige SMARCA4 Proteine), and EOMES (zeige EOMES Proteine) in TS cell self-renewal.

  10. Data suggest that Tcfap2c and Cdx2 (zeige CDX2 Proteine) cooperate to override the pluripotency program and establish the extraembryonic trophoblast maintenance program in murine embryos.

Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Protein Überblick

Protein Überblick

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.

Alternative names and synonyms associated with Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C)

  • transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (tfap2c)
  • transcription factor AP-2 gamma (TFAP2C)
  • transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (TFAP2C)
  • transcription factor ap-2 gamma (Smp_157840)
  • transcription factor AP-2 gamma (LOC100345121)
  • transcription factor AP-2 gamma (Tfap2c)
  • transcription factor AP-2, gamma (Tfap2c)
  • AA409384 Protein
  • Ap-2.2 Protein
  • ap-2g Protein
  • AP2-GAMMA Protein
  • AP2gamma Protein
  • ERF1 Protein
  • hAP-2g Protein
  • Stra2 Protein
  • Tcfap2c Protein
  • tfa2pc Protein
  • TFAP2C Protein
  • TFAP2G Protein
  • tfap2gamma Protein
  • wu:fb48g05 Protein
  • wu:fb49c04 Protein
  • zgc:92088 Protein

Bezeichner auf Proteinebene für TFAP2C

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) , transcription factor AP-2 gamma , transcription factor ap-2 gamma , transcription factor AP-2 gamma-like , activating enhancer binding protein 2 gamma , activator protein 2 gamma , activating enhancer-binding protein 2 gamma , estrogen receptor factor 1 , transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) , transcription factor ERF-1 , fb48g05 , fb49c04 , AP2-gamma , stimulated by retinoic acid gene 2

GENE ID SPEZIES
496506 Xenopus (Silurana) tropicalis
705384 Macaca mulatta
747174 Pan troglodytes
8343150 Schistosoma mansoni
100345121 Oryctolagus cuniculus
100400638 Callithrix jacchus
100470360 Ailuropoda melanoleuca
100554893 Anolis carolinensis
362280 Rattus norvegicus
7022 Homo sapiens
494033 Danio rerio
398790 Xenopus laevis
419327 Gallus gallus
485941 Canis lupus familiaris
100144525 Sus scrofa
511317 Bos taurus
21420 Mus musculus
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