SORL1 (SORL1) ELISA Kits

Bezeichnung:
Sortilin-Related Receptor, L(DLR Class) A Repeats Containing ELISA Kits (SORL1)
Auf www.antikoerper-online.de finden Sie aktuell 10 Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) ELISA Kits von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SORL1 Antikörper (100) und SORL1 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 116 SORL1 Produkte verfügbar.
Synonyme:
2900010L19Rik, AI596264, AW261561, C11orf32, gp250, Lr11, LRP9, mSorLA, RGD619914, SORL1, SorLA, SorLA-1
list all ELISA KIts Gen GeneID UniProt
SORL1 6653 Q92673
SORL1 20660 O88307
Ratte SORL1 SORL1 300652  

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SORL1 (SORL1) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für SORL1 Interaktionspartner

Human Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Interaktionspartner

  1. The results of this study support the effect of SORL1 gene on the disease risks and pathognomonic surrogates of Alzheimer's disease and mild cognitive impairment.

  2. Study provides the first evidence that the sortilin-related receptor 1 gene is associated with brain functional connectivity density differences in healthy young adults.

  3. Analysis of the molecular mechanism for the association of SORL1 with obesity: there is a genetic link between neurodegeneration and metabolism that converges on the receptor SORLA

  4. This review will provide a comprehensive overview of the evidence implicating SORLA-mediated protein sorting in neurodegenerative processes, and how receptor gene variants in the human population impair functional receptor expression in sporadic but possibly also in autosomal-dominant forms of Alzheimer's disease.

  5. SorLA ectodomain, released from the cell membrane upon enzymatic cleavage of full-length SorLA, may act as an IL-6 (zeige IL6 ELISA Kits) carrier protein that stabilizes IL-6 (zeige IL6 ELISA Kits) and its capacity for trans signaling.

  6. observed a 1.5-fold enrichment of rare non-synonymous variants of sortilin-related receptor 1 in Alzheimer's disease patients

  7. This review article discusses the molecular mechanisms that govern sorting of SORLA and its cargo in multiple cell types, and why genetic defects in this receptor results in devastating diseases. [review]

  8. The presence of rare coding variants in SORL1 in three different European American cohorts: early-onset, late-onset AD (LOAD) and familial LOAD, was examined.

  9. sLR11 levels in bile may be indicative of cancer cell conditions and may serve as potential novel biomarker in patients with BTC (zeige BTC ELISA Kits) and PC

  10. SORL1 protein is involved with late onset Alzheimer's disease. [review]

Mouse (Murine) Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Interaktionspartner

  1. Analysis of the molecular mechanism for the association of SORL1 with obesity: there is a genetic link between neurodegeneration and metabolism that converges on the receptor SORLA

  2. SorLA ectodomain, released from the cell membrane upon enzymatic cleavage of full-length SorLA, may act as an IL-6 (zeige IL6 ELISA Kits) carrier protein that stabilizes IL-6 (zeige IL6 ELISA Kits) and its capacity for trans signaling.

  3. We identify binding and trafficking interactions between two of these factors, SORLA and SNX27 (zeige SNX27 ELISA Kits), and demonstrate that SNX27 (zeige SNX27 ELISA Kits) can direct trafficking of SORLA and the Abeta (zeige APP ELISA Kits) precursor APP (zeige APP ELISA Kits) to the cell surface to limit the production of Abeta (zeige APP ELISA Kits). Diversion APP (zeige APP ELISA Kits) to the cell surface through modulation of this molecular complex may represent a complimentary strategy for future development in AD treatment.

  4. LR11 regulated vascular smooth muscle cell proliferation during the progression of hypoxia-induced medial thickening in mice.

  5. Therefore, SORL1 activation by 6-shogaol provides neuronal cell survival through the inhibition of Abeta (zeige APP ELISA Kits) production. These results indicate that 6-shogaol should be regarded as an SORL1 activator and a potential preventive agent for the treatment of AD.

  6. Data strongly suggest an involvement of LR11 in mediating the harmful effects of a high-fat diet on CVD progression.

  7. Mice lacking LR11 are protected from diet-induced obesity associated with an increased browning of white adipose tissue and hypermetabolism.

  8. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 exon 17, TRAF3IP2 (zeige TRAF3IP2 ELISA Kits) exon 2, PPARG (zeige PPARG ELISA Kits) exon 6) at single nucleotide resolution in the mouse liver

  9. Data indicate that activation of alpha(2A) adrenergic receptor (alpha(2A)AR (zeige ADRA2A ELISA Kits)) signaling disrupts transgenic amyloid precursor protein (APP (zeige APP ELISA Kits)) interaction with sorting-related receptor with A repeat (SorLA) in cells and brain.

  10. SORLA-mediated trafficking of TrkB (zeige NTRK2 ELISA Kits) enhances the response of neurons to BDNF (zeige BDNF ELISA Kits).

SORL1 Antigen-Profil

Beschreibung des Gens

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.

Alternative names and synonyms associated with SORL1

  • sortilin-related receptor, L(DLR class) A repeats containing (sorl1) Elisa Kit
  • sortilin-related receptor, L(DLR class) A repeats-containing (SORL1) Elisa Kit
  • sortilin-related receptor, L(DLR class) A repeats-containing (LOC100226349) Elisa Kit
  • sortilin-related receptor, L(DLR class) A repeats-containing (sorl1) Elisa Kit
  • sortilin-related receptor, L(DLR class) A repeats containing (SORL1) Elisa Kit
  • sortilin-related receptor, LDLR class A repeats-containing (Sorl1) Elisa Kit
  • 2900010L19Rik Elisa Kit
  • AI596264 Elisa Kit
  • AW261561 Elisa Kit
  • C11orf32 Elisa Kit
  • gp250 Elisa Kit
  • Lr11 Elisa Kit
  • LRP9 Elisa Kit
  • mSorLA Elisa Kit
  • RGD619914 Elisa Kit
  • SORL1 Elisa Kit
  • SorLA Elisa Kit
  • SorLA-1 Elisa Kit

Bezeichner auf Proteinebene für SORL1

sortilin-related receptor, L(DLR class) A repeats containing , sortilin-related receptor, L(DLR class) A repeats-containing , sortilin-related receptor-like , LDLR relative with 11 ligand-binding repeats , low-density lipoprotein receptor relative with 11 ligand-binding repeats , mosaic protein LR11 , sortilin-related receptor , sorting protein-related receptor containing LDLR class A repeats , LR11 , sorLA , sorLA-1

GENE ID SPEZIES
100566946 Anolis carolinensis
582560 Strongylocentrotus purpuratus
713011 Macaca mulatta
100024063 Monodelphis domestica
100071572 Equus caballus
100073504 Ornithorhynchus anatinus
100226349 Taeniopygia guttata
100490681 Xenopus (Silurana) tropicalis
100524036 Sus scrofa
6653 Homo sapiens
479408 Canis lupus familiaris
533166 Bos taurus
395998 Gallus gallus
100009378 Oryctolagus cuniculus
20660 Mus musculus
300652 Rattus norvegicus
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