anti-SORL1 (SORL1) Antikörper

Bezeichnung:
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing Antikörper (SORL1)
Auf www.antikoerper-online.de finden Sie aktuell 98 Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SORL1 Kits (9) und SORL1 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 113 SORL1 Produkte verfügbar.
Synonyme:
2900010L19Rik, AI596264, AW261561, C11orf32, gp250, Lr11, LRP9, mSorLA, RGD619914, SORL1, SorLA, SorLA-1
Alle Antikörper anzeigen Gen GeneID UniProt
SORL1 6653 Q92673
SORL1 20660 O88307
SORL1 300652  

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Meistgesuchte Reaktivitäten zu anti-SORL1 (SORL1) Antikörper

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anti-Human SORL1 Antikörper:

anti-Mouse (Murine) SORL1 Antikörper:

anti-Rat (Rattus) SORL1 Antikörper:

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Am meisten referenzierte anti-SORL1 Antikörper

  1. Human Monoclonal SORL1 Primary Antibody für ELISA, WB - ABIN1724683 : Scherzer, Offe, Gearing, Rees, Fang, Heilman, Schaller, Bujo, Levey, Lah: Loss of apolipoprotein E receptor LR11 in Alzheimer disease. in Archives of neurology 2004 (PubMed)
    Zeige alle 3 Referenzen für 1724683

  2. Human Monoclonal SORL1 Primary Antibody für ICC, IHC - ABIN1724674 : Gabrielsson, Olofsson, Sjögren, Jernås, Elander, Lönn, Rudemo, Carlsson: Evaluation of reference genes for studies of gene expression in human adipose tissue. in Obesity research 2005 (PubMed)
    Zeige alle 3 Referenzen für 1724674

  3. Human Polyclonal SORL1 Primary Antibody für EIA, IP - ABIN493474 : Taira, Bujo, Hirayama, Yamazaki, Kanaki, Takahashi, Ishii, Miida, Schneider, Saito: LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro. in Arteriosclerosis, thrombosis, and vascular biology 2001 (PubMed)
    Zeige alle 3 Referenzen für 493474

  4. Human Monoclonal SORL1 Primary Antibody für IHC (fro), FACS - ABIN1109103 : Shah, Yu: sorLA: sorting out APP. in Molecular interventions 2006 (PubMed)
    Zeige alle 3 Referenzen für 1109103

  5. Human Monoclonal SORL1 Primary Antibody für IF, WB - ABIN968682 : Jacobsen, Madsen, Moestrup, Lund, Tommerup, Nykjaer, Sottrup-Jensen, Gliemann, Petersen: Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 3 Referenzen für 968682

  6. Fly (Calliphora) Monoclonal SORL1 Primary Antibody für IHC, WB - ABIN968899 : Posse De Chaves, Vance, Campenot, Kiss, Vance: Uptake of lipoproteins for axonal growth of sympathetic neurons. in The Journal of biological chemistry 2000 (PubMed)
    Zeige alle 3 Referenzen für 968899

  7. Mouse (Murine) Polyclonal SORL1 Primary Antibody für ELISA, WB - ABIN184579 : Jacobsen, Madsen, Jacobsen, Nielsen, Gliemann, Petersen: Activation and functional characterization of the mosaic receptor SorLA/LR11. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 2 Referenzen für 184579

Weitere Antikörper gegen SORL1 Interaktionspartner

Human Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Interaktionspartner

  1. observed a 1.5-fold enrichment of rare non-synonymous variants of sortilin-related receptor 1 in Alzheimer's disease patients

  2. This review article discusses the molecular mechanisms that govern sorting of SORLA and its cargo in multiple cell types, and why genetic defects in this receptor results in devastating diseases. [review]

  3. The presence of rare coding variants in SORL1 in three different European American cohorts: early-onset, late-onset AD (LOAD) and familial LOAD, was examined.

  4. sLR11 levels in bile may be indicative of cancer cell conditions and may serve as potential novel biomarker in patients with BTC (zeige BTC Antikörper) and PC

  5. SORL1 protein is involved with late onset Alzheimer's disease. [review]

  6. The DNA methylation (zeige HELLS Antikörper) of the SORL1 5'-flanking region may significantly influence the manifestation of mild cognitive impairment in T2 Diabetes mellitus, and might be associated with its neurocognitive presentation.

  7. Findings provide evidence that sortilin (zeige SORT1 Antikörper) receptor 1 rs3824968 modulates regional gray matter volume and is associated with brain trajectory during the adult lifespan.

  8. Serum LR11 reflects the development of vascular lesions in patients with serious coronary artery lesions.

  9. Elevated sLR11 levels may increase the cardiovascular disease risk especially in subjects with delayed clearance of triglyceride-rich remnants, such as in familial hypercholesterolemia patients.

  10. CLF-1 (zeige CRLF1 Antikörper), based on its binding site for CLC (zeige CLC Antikörper) and on two additional and independent sites for CNTFRalpha (zeige CNTFR Antikörper) and sorLA, is a key player in CLC (zeige CLC Antikörper) and CNTFRalpha (zeige CNTFR Antikörper) signaling and turnover.

Mouse (Murine) Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Interaktionspartner

  1. We identify binding and trafficking interactions between two of these factors, SORLA and SNX27 (zeige SNX27 Antikörper), and demonstrate that SNX27 (zeige SNX27 Antikörper) can direct trafficking of SORLA and the Abeta (zeige APP Antikörper) precursor APP (zeige APP Antikörper) to the cell surface to limit the production of Abeta (zeige APP Antikörper). Diversion APP (zeige APP Antikörper) to the cell surface through modulation of this molecular complex may represent a complimentary strategy for future development in AD treatment.

  2. LR11 regulated vascular smooth muscle cell proliferation during the progression of hypoxia-induced medial thickening in mice.

  3. Therefore, SORL1 activation by 6-shogaol provides neuronal cell survival through the inhibition of Abeta (zeige APP Antikörper) production. These results indicate that 6-shogaol should be regarded as an SORL1 activator and a potential preventive agent for the treatment of AD.

  4. Data strongly suggest an involvement of LR11 in mediating the harmful effects of a high-fat diet on CVD progression.

  5. Mice lacking LR11 are protected from diet-induced obesity associated with an increased browning of white adipose tissue and hypermetabolism.

  6. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 exon 17, TRAF3IP2 (zeige TRAF3IP2 Antikörper) exon 2, PPARG (zeige PPARG Antikörper) exon 6) at single nucleotide resolution in the mouse liver

  7. Data indicate that activation of alpha(2A) adrenergic receptor (alpha(2A)AR (zeige ADRA2A Antikörper)) signaling disrupts transgenic amyloid precursor protein (APP (zeige APP Antikörper)) interaction with sorting-related receptor with A repeat (SorLA) in cells and brain.

  8. SORLA-mediated trafficking of TrkB (zeige NTRK2 Antikörper) enhances the response of neurons to BDNF (zeige BDNF Antikörper).

  9. SorLA acts as sorting receptor for the GDNF (zeige GDNF Antikörper)/GFRalpha1 (zeige GFRA1 Antikörper) complex, directing it from the cell surface to endosomes.

  10. sLR11 regulates the hypoxia-enhanced adhesion of HSPCs via an uPAR (zeige PLAUR Antikörper)-mediated pathway that stabilizes the hematological pool size by controlling cell attachment to the BM niche.

SORL1 Antigen-Profil

Beschreibung des Gens

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.

Alternative names and synonyms associated with SORL1

  • sortilin-related receptor, L(DLR class) A repeats containing (sorl1) Antikörper
  • sortilin-related receptor, L(DLR class) A repeats-containing (SORL1) Antikörper
  • sortilin-related receptor, L(DLR class) A repeats-containing (LOC100226349) Antikörper
  • sortilin-related receptor, L(DLR class) A repeats-containing (sorl1) Antikörper
  • sortilin-related receptor, L(DLR class) A repeats containing (SORL1) Antikörper
  • sortilin-related receptor, LDLR class A repeats-containing (Sorl1) Antikörper
  • 2900010L19Rik Antikörper
  • AI596264 Antikörper
  • AW261561 Antikörper
  • C11orf32 Antikörper
  • gp250 Antikörper
  • Lr11 Antikörper
  • LRP9 Antikörper
  • mSorLA Antikörper
  • RGD619914 Antikörper
  • SORL1 Antikörper
  • SorLA Antikörper
  • SorLA-1 Antikörper

Bezeichner auf Proteinebene für SORL1

sortilin-related receptor, L(DLR class) A repeats containing , sortilin-related receptor, L(DLR class) A repeats-containing , sortilin-related receptor-like , LDLR relative with 11 ligand-binding repeats , low-density lipoprotein receptor relative with 11 ligand-binding repeats , mosaic protein LR11 , sortilin-related receptor , sorting protein-related receptor containing LDLR class A repeats , LR11 , sorLA , sorLA-1

GENE ID SPEZIES
100566946 Anolis carolinensis
582560 Strongylocentrotus purpuratus
713011 Macaca mulatta
100024063 Monodelphis domestica
100071572 Equus caballus
100073504 Ornithorhynchus anatinus
100226349 Taeniopygia guttata
100490681 Xenopus (Silurana) tropicalis
100524036 Sus scrofa
6653 Homo sapiens
479408 Canis lupus familiaris
533166 Bos taurus
395998 Gallus gallus
100009378 Oryctolagus cuniculus
20660 Mus musculus
300652 Rattus norvegicus
Ausgewählte Anbieter für anti-SORL1 (SORL1) Antikörper
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