anti-LRP1 (LRP1) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 165 Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LRP1 Kits (33) und LRP1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 222 LRP1 Produkte verfügbar.
Synonyme:
A2mr, AI316852, APOER, APR, CD91, IGFBP3R, Lrp, LRP-1, LRP1A, TGFBR5
Alle Antikörper anzeigen Gen GeneID UniProt
LRP1 4035 Q07954
LRP1 16971 Q91ZX7
LRP1 299858  

Meistgesuchte Reaktivitäten zu anti-LRP1 (LRP1) Antikörper

anti-Human LRP1 Antikörper:

anti-Mouse (Murine) LRP1 Antikörper:

anti-Rat (Rattus) LRP1 Antikörper:

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Weitere Antikörper gegen LRP1 Interaktionspartner

Human Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) Interaktionspartner

  1. Poor LRP1 expression in T cells depends on shedding. Integrin ligands and CXCL12 (zeige CXCL12 Antikörper) antagonize shedding through a TSP-1 (zeige THBS1 Antikörper)-dependent pathway and ligation of CD28 (zeige CD28 Antikörper) antagonizes shedding independent of TSP-1 (zeige THBS1 Antikörper).

  2. Altered Met receptor phosphorylation and LRP1-mediated uptake in cells lacking carbohydrate-dependent lysosomal targeting

  3. LRP1 single-nucleotide polymorphism is associated with migraine.

  4. Electrostatic potential calculations suggested a competition between negatively charged GAGs and highly negatively charged complement-like domains of LRP-1 for the binding to a positively charged area of TIMP-3 (zeige TIMP3 Antikörper) as an underlying mechanism.

  5. findings revealed a pH-dependent release of the ligand associated with a conformational change of the receptor. In summary, this investigation of the complete LRP1 ectodomain significantly advances our understanding of this important receptor and provides the basis for further elucidating the mechanism of action of LRP1 in a whole and integrated system.

  6. although fVIII (zeige F8 Antikörper) bound avidly to soluble forms of clusters II and IV from LRP1, only soluble cluster IV competed with the binding of fVIII (zeige F8 Antikörper) to full-length LRP1, revealing that cluster IV represents the major fVIII (zeige F8 Antikörper) binding site in LRP1.

  7. LRP1 protein expression in human abdominal aortic aneurysm tissues may be down-regulated by miR (zeige MLXIP Antikörper)-205 through translational inhibition, resulting in a reduced clearance of pericellular MMP-9 (zeige MMP9 Antikörper), promoting aneurysm formation.

  8. data also reveal that D1D2 is able to bind to a second distinct site on LRP1 to form a monovalent complex. The studies confirm the canonical model for ligand recognition by this class of receptors, which is initiated by pairs of lysine residues that dock into acidic pockets on the receptor

  9. results indicate that genetic variations in LRP1 and ULK4 contribute to risk for presenting with an acute aortic dissection

  10. Considering that LRP-1, by mediating the clearance of matrix metalloproteinases, is involved in the regulation of extracellular matrix remodeling and cell migration, we conclude that a decreased expression of LRP-1 could be involved with the increasing activity of MMPs shown in cancers.

Mouse (Murine) Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) Interaktionspartner

  1. This study demonstrated that LRP1 suppresses microglial activation by modulating JNK (zeige MAPK8 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) signaling pathways. Down-regulation of LRP1 levels and the increased pro-inflammatory signaling may result in a vicious cycle, in which the two events synergistically promote microglial activation

  2. ApoC-III (zeige APOC3 Antikörper) inhibits turnover of TG-rich lipoproteins primarily through a hepatic clearance mechanism mediated by the LDLR (zeige LDLR Antikörper)/LRP1 axis

  3. These results provide evidence supporting a key role for the p38 MAPK (zeige MAPK14 Antikörper) signaling pathway which is involved in the regulation of Abeta1-42 internalization in the parietal cortex and hippocampus of mouse through LRP1 in vivo.

  4. BMPER (zeige BMPER Antikörper)/low-density lipoprotein receptor-related protein 1 axis plays a pivotal role in pulmonary inflammatory response.

  5. report that LRP1 expression is rapidly lost as oligodendrocyte progenitor cells differentiate, and is absent from all oligodendrocytes, including newborn oligodendrocytes

  6. Results show evidence of low-density lipoprotein receptor-related protein 1 ( (LRP1) expression and activity modulation by Intravenous immunoglobulin (IVIg), and support the role of LRP1 as a partner of IVIg in the execution of its neuroprotective effects.

  7. LRP1 deficiency in mature adipocytes promotes diet-induced inflammation and atherosclerosis.

  8. TNF-alpha (zeige TNF Antikörper) blockade exerts antiatherosclerotic effects that are dependent on the presence of macrophage LRP1.

  9. these results documented that LRP1 deficiency in hepatocytes promotes lipid accumulation and lipotoxicity through lysosomal-mitochondrial permeabilization and ER stress that ultimately result in cell death. Hence, LRP1 dysfunction may be a major risk factor in fatty liver disease progression.

  10. A critical role was determined for astrocytic LRP1 in brain for clearing amyloid-beta accumulation.

LRP1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.

Alternative names and synonyms associated with LRP1

  • low density lipoprotein receptor-related protein 1 (LRP1) Antikörper
  • low density lipoprotein receptor-related protein 1 (Lrp1) Antikörper
  • A2mr Antikörper
  • AI316852 Antikörper
  • APOER Antikörper
  • APR Antikörper
  • CD91 Antikörper
  • IGFBP3R Antikörper
  • Lrp Antikörper
  • LRP-1 Antikörper
  • LRP1A Antikörper
  • TGFBR5 Antikörper

Bezeichner auf Proteinebene für LRP1

low density lipoprotein receptor-related protein 1 , prolow-density lipoprotein receptor-related protein 1-like , LRP-1 , TbetaR-V/LRP-1/IGFBP-3 receptor , alpha-2-macroglobulin receptor , apolipoprotein E receptor , prolow-density lipoprotein receptor-related protein 1 , type V tgf-beta receptor , alpha 2-macroglobulin receptor , lipoprotein receptor-related protein , low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) , low-density lipoprotein receptor-related protein/alpha-2 macroglobulin receptor , low-density lipoprotein receptor-related protein 1

GENE ID SPEZIES
100414789 Callithrix jacchus
4035 Homo sapiens
16971 Mus musculus
299858 Rattus norvegicus
100009547 Oryctolagus cuniculus
100726418 Cavia porcellus
100627964 Sus scrofa
481124 Canis lupus familiaris
533894 Bos taurus
396170 Gallus gallus
101120656 Ovis aries
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