anti-Human USH2A Antikörper für Immunohistochemistry (Frozen Sections)

Recommended USH2A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Usher Syndrome 2A (Autosomal Recessive, Mild) (USH2A) Antikörper
  • si:ch211-279e11.1
  • RP39
  • US2
  • USH2
  • dJ1111A8.1
  • A930011D15Rik
  • A930037M10Rik
  • Gm676
  • Gm983
  • Mush2a
  • Usherin
  • RGD1560269
  • Usher syndrome 2A (autosomal recessive, mild)
  • USH2A
  • ush2a
  • Ush2a
Epitop
C-Term
6
6
3
3
2
2
2
Reaktivität
Human
12
8
7
7
Wirt
Kaninchen
12
Klonalität
Polyklonal
Konjugat
Dieser USH2A Antikörper ist unkonjugiert
3
3
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
11
11
10
9
8
8
8
Hersteller
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Produktnummer ABIN1109452
$ 533.50
Zzgl. Versandkosten $45.00

General

Antigen Usher Syndrome 2A (Autosomal Recessive, Mild) (USH2A) Antikörper
Epitop C-Term
(6), (6), (3), (3), (2), (2), (2)
Reaktivität Human
(12), (8), (7), (7)
Wirt Kaninchen
(12)
Klonalität
Polyklonal
Konjugat Dieser USH2A Antikörper ist unkonjugiert
(3), (3)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(11), (11), (10), (9), (8), (8), (8)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-USH2A Antikörper

Target Details USH2A Anwendungsinformationen Handhabung Bilder
Spezifität This antibody reacts with Human 570 kDa USH2A protein. Cross reacts with Rat, Mouse and other species.
Kreuzreaktivität (Details) Species reactivity (tested):Human, Mouse, Rat.
Reinigung Serum
Immunogen Synthetic peptide derived from C-terminal domain of Human Ush2A

Target Details USH2A

Produktdetails anti-USH2A Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Usherin / USH2A (USH2A Antibody Abstract)
Hintergrund The Usher 2A gene expresses an extra cellular matrix protein that resembles unconventional Myosin and do not appear to have any un-conventional functional correlations. It is expressed primarily in retina and cochlea and may be important in the development and homeostasis of the inner ear and retina. The human Usher Syndrome 2A (Ush2A) protein has several functional domains (Laminin type EGF like domain, Laminin-Type epidermal growth factor like domain and a fibronectin type 3 like domain). The protein has a single transmembrane domain that anchor the protein to the cell membrane, the rest of the protein stays outside the cell. Defects in the USH2A gene are the most common cause of deafness and blindness in adults and affect 3-6 % children born with hearing impairments. The affected individuals have sensory-neural deficiencies at birth and subsequently develop progressive retinitis pigmentosa (RP). Three forms of Usher syndrome have been characterized, Usher Type 1, II and III which can be distinguish based on severity of hearing loss and vestibular involvement. Type I patents are profoundly deaf while type II (most common form of Usher syndrome) patients are mildly deaf but have normal in vestibular responses.Synonyms: Usher syndrome type IIa protein, Usher syndrome type-2A protein
Gen-ID 7399
NCBI Accession NP_009054
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-USH2A Antikörper Target Details USH2A Handhabung Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-USH2A Antikörper Target Details USH2A Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Rekonstitution Restore in distilled water.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.