anti-Mucolipin 3 (Mcoln3) Antikörper

Bezeichnung:
anti-Mucolipin 3 Antikörper (Mcoln3)
Auf www.antikoerper-online.de finden Sie aktuell 48 Mucolipin 3 (Mcoln3) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 56 Mucolipin 3 Produkte verfügbar.
Synonyme:
6720490O21Rik, MCOLN3, trp-ml3, trpml3, Va
Alle Antikörper anzeigen Gen GeneID UniProt
Mcoln3 171166 Q8R4F0
Mcoln3 55283 Q8TDD5
Mcoln3 308022  

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Meistgesuchte Reaktivitäten zu anti-Mucolipin 3 (Mcoln3) Antikörper

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Am meisten referenzierte anti-Mucolipin 3 Antikörper

  1. Human Polyclonal Mcoln3 Primary Antibody für IHC, WB - ABIN350500 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)
    Zeige alle 2 Referenzen für 350500

  2. Mouse (Murine) Polyclonal Mcoln3 Primary Antibody für IHC, WB - ABIN350489 : Di Palma, Belyantseva, Kim, Vogt, Kachar, Noben-Trauth: Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 2 Referenzen für 350489

  3. Human Polyclonal Mcoln3 Primary Antibody für IHC, WB - ABIN350496 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Zeige alle 2 Referenzen für 350496

  4. Human Polyclonal Mcoln3 Primary Antibody für WB - ABIN657789 : Kim, Yamaguchi, Li, So, Muallem: Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 2 Referenzen für 657789

  5. Rat (Rattus) Polyclonal Mcoln3 Primary Antibody für IHC, WB - ABIN350495 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  6. Cow (Bovine) Polyclonal Mcoln3 Primary Antibody für WB - ABIN2776223 : Kim, Li, Tjon-Kon-Sang, So, Kiselyov, Soyombo, Muallem: A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. in The EMBO journal 2008 (PubMed)

Weitere Antikörper gegen Mucolipin 3 Interaktionspartner

Mouse (Murine) Mucolipin 3 (Mcoln3) Interaktionspartner

  1. Study shows that, when uropathogenic E. coli infect bladder epithelial cells, they are targeted by autophagy but avoid degradation because of their capacity to neutralize lysosomal pH. This change is detected by TRPML3, TRPML3 activation then spontaneously initiates lysosome exocytosis, resulting in expulsion of exosome-encased bacteria.

  2. Trpml3 inactivation does not lead to hearing and vestibular impairment in mice

  3. Results describe the expression and subcellular distribution of TRPML3 in the inner ear as well as in other sensory organs.

  4. prominent role for MCOLN3 in regulating Ca(2 (zeige CA2 Antikörper)+) homeostasis at the endosomal pathway

  5. Mutations are associated with deafness and pigmentation defects in varitint-waddler (Va) mice

  6. there is a hierarchy controlling the subcellular distributions of the TRPMLs such that TRPML1 (zeige MCOLN1 Antikörper) and TRPML2 (zeige MCOLN2 Antikörper) dictate the localization of TRPML3 and not vice versa

  7. TRPML3 is critical for stereocilia bundle formation during development and may function during endocytosis or exocytosis.

  8. This study provides the first direct mechanistic link of a mutation in a TRPML3 with mammalian hearing loss.

  9. TRPML3(A419P) and (I362T+A419P) at physiological potentials may have a role in hair cell degeneration and deafness

  10. The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence. (Review)

Human Mucolipin 3 (Mcoln3) Interaktionspartner

  1. these results suggest that TRPML3 plays a role in autophagosome maturation through the interaction with GATE16 (zeige GABARAPL2 Antikörper), by providing Ca(2 (zeige CA2 Antikörper)+) in the fusion process.

  2. TRPML3 and TRPV5 (zeige TRPV5 Antikörper) heteromers could have a biological function

  3. Negatively charged amino acids in the extracellular loops of TRPML3 may interfere with the observed sodium inhibition.

  4. TRPML 1 (zeige MCOLN1 Antikörper), 2 and 3 assemblies regulated cell viability and starvation-induced autophagy.

  5. analysis of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation

  6. there is a hierarchy controlling the subcellular distributions of the TRPMLs such that TRPML1 (zeige MCOLN1 Antikörper) and TRPML2 (zeige MCOLN2 Antikörper) dictate the localization of TRPML3 and not vice versa

  7. TRPML3(A419P) and (I362T+A419P) at physiological potentials may have a role in hair cell degeneration and deafness

  8. First characterization of wild-type TRPML3 calcium-permeable channel properties and its regulation by extracytosolic (luminal)hydrogen ion (H+).

  9. The deaf-waddler (zeige ATP2B2 Antikörper) isoform of PMCA2 (zeige ATP2B2 Antikörper), operating at 30% efficacy, showed a significantly decreased ability to rescue the Ca(2 (zeige CA2 Antikörper)+) loading of cells expressing TRPML3(A419P).

  10. Results show that mucolipin 3 is a novel calcium channel that plays a crucial role in the regulation of cargo trafficking along the endosomal pathway.

Mucolipin 3 (Mcoln3) Antigen-Profil

Beschreibung des Gens

This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Mucolipin 3 (Mcoln3)

  • mucolipin 3 (MCOLN3) Antikörper
  • mucolipin 3 (mcoln3) Antikörper
  • mucolipin 3 (Mcoln3) Antikörper
  • 6720490O21Rik Antikörper
  • MCOLN3 Antikörper
  • trp-ml3 Antikörper
  • trpml3 Antikörper
  • Va Antikörper

Bezeichner auf Proteinebene für anti-Mucolipin 3 (Mcoln3) Antikörper

mucolipin 3 , mucolipin-3-like , mucolipin-3 , varitint-waddler

GENE ID SPEZIES
429091 Gallus gallus
469371 Pan troglodytes
549558 Xenopus (Silurana) tropicalis
100064441 Equus caballus
100412379 Callithrix jacchus
100447374 Pongo abelii
100472258 Ailuropoda melanoleuca
100554956 Anolis carolinensis
100591172 Nomascus leucogenys
171166 Mus musculus
55283 Homo sapiens
308022 Rattus norvegicus
444109 Xenopus laevis
490185 Canis lupus familiaris
100049666 Sus scrofa
514345 Bos taurus
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