anti-Human GJB6 Antikörper für Enzyme Immunoassay

Recommended GJB6 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Gap Junction Protein, beta 6, 30kDa (GJB6) Antikörper
  • connexin-26
  • cx26
  • cx30
  • dfna3
  • dfna3a
  • dfnb1
  • dfnb1a
  • ed2
  • edh
  • gjb6
  • hed
  • nsrd1
  • ppk
  • AA958971
  • Cx30
  • D14Bwg0506e
  • CX30
  • DFNA3
  • DFNA3B
  • DFNB1B
  • ECTD2
  • ED2
  • EDH
  • HED
  • HED2
  • CX31
  • connexin 30
  • gap junction protein, beta 2, 26kDa
  • gap junction protein, beta 6, 30kDa
  • gap junction protein, beta 6
  • LOC387566
  • gjb2
  • GJB6
  • Gjb6
Epitop
AA 95-124, N-Term
18
4
3
2
2
1
1
1
Reaktivität
Human
51
13
12
5
2
1
1
1
1
1
Wirt
Kaninchen
36
13
2
Klonalität
Polyklonal
Konjugat
Dieser GJB6 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
35
35
23
3
1
1
1
Hersteller
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Bilder

Produktnummer ABIN357095
$ 390.50
Zzgl. Versandkosten $45.00

General

Antigen Gap Junction Protein, beta 6, 30kDa (GJB6) Antikörper
Epitop AA 95-124, N-Term
(18), (4), (3), (2), (2), (1), (1), (1)
Reaktivität Human
(51), (13), (12), (5), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(36), (13), (2)
Klonalität
Polyklonal
Konjugat Dieser GJB6 Antikörper ist unkonjugiert
(3), (3), (3), (3), (3), (3)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(35), (35), (23), (3), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GJB6 Antikörper

Target Details GJB6 Anwendungsinformationen Handhabung Referenzen für anti-GJB6 Antikörper (ABIN357095) Bilder
Spezifität This antibody detects GJB6 at N-term.
Reinigung Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 95~124 amino acids from the N-terminal region of Human GJB6.
Isotyp Ig

Target Details GJB6

Produktdetails anti-GJB6 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-GJB6 Antikörper (ABIN357095) Bilder zurück nach oben
Antigen
Andere Bezeichnung GJB6 / Cx30 (GJB6 Antibody Abstract)
Hintergrund Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.Synonyms: Connexin-30, Gap junction beta-6 protein
Molekulargewicht 30387 Da
Gen-ID 10804, 9606
UniProt O95452
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-GJB6 Antikörper Target Details GJB6 Handhabung Referenzen für anti-GJB6 Antikörper (ABIN357095) Bilder zurück nach oben
Applikationshinweise ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GJB6 Antikörper Target Details GJB6 Anwendungsinformationen Referenzen für anti-GJB6 Antikörper (ABIN357095) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-GJB6 Antikörper (ABIN357095)

Produktdetails anti-GJB6 Antikörper Target Details GJB6 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Beltramello, Bicego, Piazza, Ciubotaru, Mammano, DAndrea: "Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells." in: Biochemical and biophysical research communications, Vol. 305, Issue 4, pp. 1024-33, 2003

Common, Becker, Di, Leigh, OToole, Kelsell: "Functional studies of human skin disease- and deafness-associated connexin 30 mutations." in: Biochemical and biophysical research communications, Vol. 298, Issue 5, pp. 651-6, 2002

Bilder

Produktdetails anti-GJB6 Antikörper Target Details GJB6 Anwendungsinformationen Handhabung Referenzen für anti-GJB6 Antikörper (ABIN357095) zurück nach oben
Bilder des Herstellers
 image for anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody (ABIN357095) anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody
 image for anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody (ABIN357095) anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody (Image 2)
 image for anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody (ABIN357095) anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (AA 95-124), (N-Term) antibody (Image 3)