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Human Filaggrin ELISA Kit für Sandwich ELISA - ABIN423702
Weichenthal, Ruether, Schreiber, Nair, Voorhees, Schwarz, Kabelitz, Christophers, Elder, Jenisch: Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort. in The Journal of investigative dermatology 2007
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Visceral adipose tissue-derived factors stimulate cell transformation through FGFR-1 (zeige FGFR1 ELISA Kits).
the localization of FGF9 and its receptors at different embryonic and postnatal stages in mice testes, was examined.
CDC42 (zeige CDC42 ELISA Kits) is involved in the trafficking of FGF receptors to the cell membrane to regulate epicardium formation.
MAPK (zeige MAPK1 ELISA Kits) cascades participate in osteogenesis, but only the ERK (zeige EPHB2 ELISA Kits) signaling pathway responds to FGFR1 (zeige FGFR1 ELISA Kits).
It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor (zeige FGFR2 ELISA Kits) 2, in the oligodendr
data suggest that FGF2 (zeige FGF2 ELISA Kits) levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (zeige NR3C1 ELISA Kits) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (zeige FGFR1 ELISA Kits), FGFR2 (zeige FGFR2 ELISA Kits), and FGFR3 (zeige FGFR3 ELISA Kits).
increased activity of the PI3K/AKT (zeige AKT1 ELISA Kits) signaling pathway in Pelo (zeige PELO ELISA Kits)-deficient skin might conflict with the dephosphorylation of profilaggrin and thereby affect its proper processing into filaggrin monomers and ultimately the epidermal differentiation
clearly demonstrate the different specificity of FGF12 (zeige FGF12 ELISA Kits)-FGFR1c2 and FGF22 (zeige FGF22 ELISA Kits)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling
The study supports a pro-adipogenic role for betaKlotho (zeige KLB ELISA Kits) in skeletal muscle fibro/adipogenesis and calls for further research on involvement of the FGF-FGFR (zeige FGFR2 ELISA Kits)-betaKlotho (zeige KLB ELISA Kits) axis in the fibro/adipogenic infiltration associated with functional deterioration of skeletal muscle in aging and muscular dystrophy.
These new findings reveal that the FGF21-betaKlotho-FGFR1 signaling axis plays roles in maintaining phospholipid homeostasis and the dynamic functions of the lipid droplet, whereas protecting against ER stress, and suggest a potential link of phospholipid biosynthesis, lipid droplet dynamics, ER stress, and energy homeostasis in adipose tissue coordinated by this signaling axis.
FLG mutation is associated with IgE sensitization to peanut but not to other allergens in Swedish children up to 16 years of age
Erythemal doses of ultraviolet B exert acute effects on profilaggrin mRNA and filaggrin protein in human skin in vivo.
FLG (zeige FGFR1 ELISA Kits) mutations are associated with early onset of atopic dermatitis, more severe clinical course of disease, and a significantly increased risk ofMolluscum contagiosum sustained skin infection
Study conducted in Croatia found a low frequency of FLG (zeige FGFR1 ELISA Kits) null-mutations in general population (2.6%) and did not confirm FLG (zeige FGFR1 ELISA Kits) null-mutations as an etiological factor for Atopy and Atopic disease in the studied population.
women with FLG (zeige FGFR1 ELISA Kits) mutations may have an increased risk of AD flares during pregnancy and of enduring postpartum problems attributable to perineal trauma during delivery.
FLG (zeige FGFR1 ELISA Kits) mutations are risk factors for atopic dermatitis in Finns, but disease severity and treatment response were independent of patient FLG (zeige FGFR1 ELISA Kits) status.
Patients with both atopic dermatitis and common filaggrin gene mutations are more frequently affected by reduced health-related quality of life
Multiple lines of evidence suggest that FLG (zeige FGFR1 ELISA Kits) genetic variation, have little or no effect on fitness in modern humans. Haplotype-level analysis revealed a recent selective sweep which increased the allele frequency of the Huxian haplogroup in Asian populations.
FLG (zeige FGFR1 ELISA Kits) mutations lead to alterations in epidermal eicosanoid metabolism in atopic dermatitis patients
Filaggrin gene mutations are risk factors for the presence and persistence of atopic dermatitis and explain the discordance of atopic dermatitis within dizygotic twin pairs.
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
, basic fibroblast growth factor receptor 1
, proto-oncogene c-Fgr
, epidermal filaggrin
, Filaggrin (profilaggrin)
, keratin intermediate filament-associated protein