anti-Maus E-cadherin Antikörper für Immunofluorescence

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • dZ71B9.1
  • si:dz180o5.1
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • CDH1
  • CDH16
  • HPT-1
  • HPT1
  • arc-1
  • cd324
  • cdhe
  • ecad
  • cad17
  • hpt1
  • cdh16
  • hpt-1
  • LI-cadherin
  • cadherin-17
  • b-cadherin
  • cdh1-a
  • cdhp
  • hjmd
  • pcad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • Arc1
  • cadherin 1, type 1, E-cadherin (epithelial)
  • si:busm1-180o5.2
  • cadherin 1, epithelial
  • cadherin 1
  • si:busm1-180o5.1
  • cadherin 17, LI cadherin (liver-intestine)
  • Cadherin-17
  • cadherin 3, type 1, P-cadherin (placental)
  • E-cadherin-like
  • Aerobic running capacity QTL 1
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • si:busm1-180o5.1
  • CDH17
  • cad17
  • cdh17
  • cdh3-a
  • LOC100356548
  • Arunc1
Epitop
Middle Region
98
35
35
31
28
19
16
15
15
14
13
10
6
6
6
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
833
256
145
40
25
15
8
7
7
6
5
4
3
1
1
1
1
1
1
1
1
1
Wirt
Kaninchen
567
273
51
25
2
Klonalität
Polyklonal
Konjugat
Dieser E-cadherin Antikörper ist unkonjugiert
43
40
38
27
24
21
19
19
17
16
15
13
13
13
13
12
12
11
10
10
9
9
6
4
4
3
3
3
3
3
3
2
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
650
399
285
214
193
174
164
90
88
38
23
14
13
12
10
7
6
6
4
4
2
2
2
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN2784498
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.920952 ABIN265912 ICC IHC (fro) IF IP IHC MA WB Rat IgG1 Anmelden zum Anzeigen DECMA-1 2
11.920952 ABIN967801 IF IP IHC WB Mouse IgG2a, kappa C-Term Anmelden zum Anzeigen 36-E 5
11.920952 ABIN967800 IF IP IHC WB Mouse IgG2a, kappa C-Term Anmelden zum Anzeigen 36-E 5
11.920952 ABIN2854751 ICC IF IP IHC (p) WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal
11.920952 ABIN4306578 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal
1 ABIN265314 EIA IF IHC (p) WB Rabbit Arg3 Anmelden zum Anzeigen Polyclonal
1 ABIN4306562 CyTOF FACS ICC IF IHC IHC (fro) IP WB Mouse IgG1 Anmelden zum Anzeigen 67A4 1
1 ABIN4306576 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 7H12 6
1 ABIN3184389 ELISA IF IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN498093 IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN4903533 FACS IF IHC WB Mouse IgG Anmelden zum Anzeigen
1 ABIN4306563 ICC IF IHC IHC (fro) IP MA WB Rat IgG1 Anmelden zum Anzeigen DECMA-1
1 ABIN198432 FACS IHC (fro) IF IHC (p) IP WB Rat IgG2a Anmelden zum Anzeigen ECCD-2
1 ABIN2891383 IF IHC (p) WB Rabbit Arg868 Anmelden zum Anzeigen Polyclonal
1 ABIN4959637 CyTOF FACS ICC IF IHC (p) WB Mouse IgG1 kappa Anmelden zum Anzeigen 4A2
1 ABIN4959638 CyTOF FACS ICC IF IHC (p) WB Mouse IgG1 kappa Anmelden zum Anzeigen 4A2
1 ABIN2216879 FACS IF IP IHC WB Rat IgG2a Anmelden zum Anzeigen 3G44
1 ABIN1083590 IF ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1083589 IF ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN4306582 FACS ICC IF IHC IHC (fro) IP WB PerCP Mouse IgG1 Anmelden zum Anzeigen 67A4

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Epitop Middle Region
(98), (35), (35), (31), (28), (19), (16), (15), (15), (14), (13), (10), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
(833), (256), (145), (40), (25), (15), (8), (7), (7), (6), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(567), (273), (51), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser E-cadherin Antikörper ist unkonjugiert
(43), (40), (38), (27), (24), (21), (19), (19), (17), (16), (15), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (2)
Applikation Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(650), (399), (285), (214), (193), (174), (164), (90), (88), (38), (23), (14), (13), (12), (10), (7), (6), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974746.
Sequenz QEITSYTAQE PDTFMEQKIT YRIWRDTANW LEINPDTGAI STRAELDRED
Homologie Cow: 93%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 85%
Produktmerkmale This is a rabbit polyclonal antibody against CDH1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CDH1

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Antigen
Andere Bezeichnung CDH1 (CDH1 Antibody Abstract)
Hintergrund Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Protein Interaction Partner: UBC, MDM2, UCHL3, CDC27, PTEN, CTNNB1, PIP5K1C, CTNND1, CBLL1, RNF2, GMNN, LMNA, KRT18, KRT9, KRT8, KRT1, IGHA1, HSPD1, HSP90AA1, HSPA9, HSPA8, HSPA5, GBAS, CTNNA1, CRYAB, CFTR, C1QBP, ACTN4, ACADVL, ANP32B, NIPSNAP1, XRCC5, TGM2, SKP2, SET, RAD17, POLR2E
Protein Size: 882
Molekulargewicht 80 kDa
Gen-ID 999
NCBI Accession NM_004360, NP_004351
UniProt P12830
Forschungsgebiet Proteolysis / Ubiquitin
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 882 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-E-cadherin Antikörper (ABIN2784498)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Onder, Gupta, Mani, Yang, Lander, Weinberg: "Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways." in: Cancer research, Vol. 68, Issue 10, pp. 3645-54, 2008

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) WB Suggested Anti-CDH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (Image 3)
Immunofluorescence (IF) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) Sample Type: Rat FRTL-5 cells

Primary Antibody Dilution: 1:100