anti-Affe E-cadherin Antikörper für Flow Cytometry

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • dZ71B9.1
  • si:dz180o5.1
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • CDH1
  • CDH16
  • HPT-1
  • HPT1
  • arc-1
  • cd324
  • cdhe
  • ecad
  • cad17
  • hpt1
  • cdh16
  • hpt-1
  • LI-cadherin
  • cadherin-17
  • b-cadherin
  • cdh1-a
  • cdhp
  • hjmd
  • pcad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • Arc1
  • cadherin 1, type 1, E-cadherin (epithelial)
  • si:busm1-180o5.2
  • cadherin 1, epithelial
  • cadherin 1
  • si:busm1-180o5.1
  • cadherin 17, LI cadherin (liver-intestine)
  • Cadherin-17
  • cadherin 3, type 1, P-cadherin (placental)
  • E-cadherin-like
  • Aerobic running capacity QTL 1
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • si:busm1-180o5.1
  • CDH17
  • cad17
  • cdh17
  • cdh3-a
  • LOC100356548
  • Arunc1
Reaktivität
Human, Maus, Affe
833
256
146
39
26
16
9
8
8
6
6
4
3
1
1
1
1
1
1
1
1
1
Wirt
Maus
566
274
51
25
2
Klonalität
Monoklonal
Konjugat
Dieser E-cadherin Antikörper ist unkonjugiert
43
40
38
27
24
21
19
19
17
16
15
13
13
13
13
12
12
11
10
10
9
9
6
4
4
3
3
3
3
3
3
2
Applikation
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
650
398
285
215
193
173
164
90
88
38
23
14
13
12
10
7
6
6
4
4
2
2
2
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN969036
$ 393.80
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.052211 ABIN4306576 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 7H12 6
14.052211 ABIN1106272 EIA FACS IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 7H12 3
14.052211 ABIN1846317 FACS IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen
1 ABIN2704739 IC FACS IF IP IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN965839 FACS IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 7A2 3
1 ABIN4880240 ELISA FACS IHC WB Mouse IgG1 Anmelden zum Anzeigen 7H12
1 ABIN2618875 FACS ICC IF IHC (p) IP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN865509 FACS IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 7H12
1 ABIN1959878 ELISA FACS IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 7H12
1 ABIN4306575 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 7H12
1 ABIN4901408 ELISA FACS IHC WB Mouse IgG1 Anmelden zum Anzeigen 7H12
1 ABIN2994235 FACS IF/ICC IHC IP WB Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Reaktivität Human, Maus, Affe
(833), (256), (146), (39), (26), (16), (9), (8), (8), (6), (6), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Maus
(566), (274), (51), (25), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser E-cadherin Antikörper ist unkonjugiert
(43), (40), (38), (27), (24), (21), (19), (19), (17), (16), (15), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (2)
Applikation Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(650), (398), (285), (215), (193), (173), (164), (90), (88), (38), (23), (14), (13), (12), (10), (7), (6), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN969036) Bilder
Reinigung Ascites
Immunogen Purified recombinant fragment of human CDH1 expressed in E. Coli.
Klon 7H12
Isotyp IgG1

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN969036) Bilder zurück nach oben
Antigen
Andere Bezeichnung CDH1 (CDH1 Antibody Abstract)
Hintergrund E-Cadherin is a 120 kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells. There, it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins. In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation. Its association with catenins is necessary for cell-cell adhesion. These E-cadherin/catenin complexes associate with corical actin bundles at both the zonula adherens and the lateral adhesion plaques. Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties. E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas. Increased expression of E-Cadherin in these cells reduces invasiveness. Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.Tissue specificity: Non-neural epithelial tissues.
Molekulargewicht 135 kDa
Gen-ID 999
HGNC 999
Forschungsgebiet Proteolysis / Ubiquitin
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN969036) Bilder zurück nach oben
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN969036) Bilder zurück nach oben
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage

Referenzen für anti-E-cadherin Antikörper (ABIN969036)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Schietke, Warnecke, Wacker, Schödel, Mole, Campean, Amann, Goppelt-Struebe, Behrens, Eckardt, Wiesener: "The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1." in: The Journal of biological chemistry, Vol. 285, Issue 9, pp. 6658-69, 2010

Barrett, Lee, Lees, Prescott, Anderson, Phillips, Wesley, Parnell, Zhang, Drummond, Nimmo, Massey, Blaszczyk, Elliott, Cotterill, Dallal, Lobo, Mowat, Sanderson, Jewell, Newman, Edwards, Ahmad et al.: "Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. ..." in: Nature genetics, Vol. 41, Issue 12, pp. 1330-4, 2009

Wang, Yao, Zhang, Zhang, Zhao: "[Expression and significance of CD147 and E-cadherin in human gastric carcinoma]." in: Zhonghua zhong liu za zhi [Chinese journal of oncology], Vol. 31, Issue 7, pp. 515-9, 2009

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN969036) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (ABIN969036) Figure 1: Flow cytometric analysis of Hela cells using CDH1 mouse mAb (green) and neg...
Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (ABIN969036) Figure 2: Immunohistochemical analysis of paraffin-embedded gastric cancer tissues (l...
Western Blotting (WB) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (ABIN969036) Figure 3: Western blot analysis using CDH1 mouse mAb against LNCAP (1) ,A431 (2), DU1...