anti-Human E-cadherin Antikörper für Intracellular Flow Cytometry

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • dZ71B9.1
  • si:dz180o5.1
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • CDH1
  • CDH16
  • HPT-1
  • HPT1
  • arc-1
  • cd324
  • cdhe
  • ecad
  • cad17
  • hpt1
  • cdh16
  • hpt-1
  • LI-cadherin
  • cadherin-17
  • b-cadherin
  • cdh1-a
  • cdhp
  • hjmd
  • pcad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • Arc1
  • cadherin 1, type 1, E-cadherin (epithelial)
  • si:busm1-180o5.2
  • cadherin 1, epithelial
  • cadherin 1
  • si:busm1-180o5.1
  • cadherin 17, LI cadherin (liver-intestine)
  • Cadherin-17
  • cadherin 3, type 1, P-cadherin (placental)
  • E-cadherin-like
  • Aerobic running capacity QTL 1
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • si:busm1-180o5.1
  • CDH17
  • cad17
  • cdh17
  • cdh3-a
  • LOC100356548
  • Arunc1
Reaktivität
Human, Maus
833
256
146
40
26
16
9
8
8
6
6
4
3
1
1
1
1
1
1
1
1
1
Wirt
Ratte
567
274
50
25
2
Klonalität
Monoklonal
Konjugat
Dieser E-cadherin Antikörper ist konjugiert mit Alexa Fluor 647
43
40
38
26
24
21
19
19
17
16
15
13
13
13
13
12
12
11
10
10
9
9
6
4
4
3
3
3
3
3
3
2
Applikation
Intracellular Flow Cytometry (ICFC)
651
399
285
215
194
174
164
90
88
38
23
14
13
12
10
7
6
5
4
4
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2657175
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2662605 ICFC PE Rat IgG1 kappa Anmelden zum Anzeigen DECMA-1 7
1 ABIN2664571 ICFC Rat IgG1 kappa Anmelden zum Anzeigen DECMA-1 7
1 ABIN2657176 ICFC Alexa Fluor 647 Rat IgG1 kappa Anmelden zum Anzeigen DECMA-1 6
1 ABIN2662606 ICFC PE Rat IgG1 kappa Anmelden zum Anzeigen DECMA-1 7
1 ABIN2664572 ICFC Rat IgG1 kappa Anmelden zum Anzeigen DECMA-1 7

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Reaktivität Human, Maus
(833), (256), (146), (40), (26), (16), (9), (8), (8), (6), (6), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Ratte
(567), (274), (50), (25), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser E-cadherin Antikörper ist konjugiert mit Alexa Fluor 647
(43), (40), (38), (26), (24), (21), (19), (19), (17), (16), (15), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (2)
Applikation Intracellular Flow Cytometry (ICFC)
(651), (399), (285), (215), (194), (174), (164), (90), (88), (38), (23), (14), (13), (12), (10), (7), (6), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2657175) Bilder
Kreuzreaktivität Cynomolgus, Hund, Schwein
Reinigung The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Klon DECMA-1
Isotyp IgG1 kappa

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2657175) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD324 (CDH1 Antibody Abstract)
Hintergrund CD324, also known as E-cadherin, cadherin-1, CDH1, and UVO is a member of the cadherin superfamily. It is a calcium-dependent, transmembrane cell-cell adhesion glycoprotein composed of four extracellular cadherin repeats and a highly conserved cytoplasmic tail region. CD324 is widely expressed in epithelial cells in the colon, uterus, liver, keratinocytes, brain, heart, muscle, kidney, and pancreas as well as erythroid cells. CD324 functions as a cell adhesion molecule involved in development, bacterial pathogenesis, and tumor invasion. In bacterial pathogenesis, the ectodomain of CD324 mediates bacterial adhesion to mammalian cells, while the cytoplasmic domain is required for internalization. CD324 binds to the αEβ7 integrin to mediate cell adhesion and also interacts with a number of intracellular proteins including including erbin, ezrin, caspase-3, caspase-8, β-catenin, presenilin 1, and casein kinase II as well as other extracellular proteins including the EGF receptor.
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2657175) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN2657175) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C

Referenzen für anti-E-cadherin Antikörper (ABIN2657175)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Boggon, Murray, Chappuis-Flament, Wong, Gumbiner, Shapiro: "C-cadherin ectodomain structure and implications for cell adhesion mechanisms." in: Science (New York, N.Y.), Vol. 296, Issue 5571, pp. 1308-13, 2002

Nakagawa, Fukata, Yamaga, Itoh, Kaibuchi: "Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites." in: Journal of cell science, Vol. 114, Issue Pt 10, pp. 1829-38, 2001

Perl, Wilgenbus, Dahl, Semb, Christofori: "A causal role for E-cadherin in the transition from adenoma to carcinoma." in: Nature, Vol. 392, Issue 6672, pp. 190-3, 1998

Berx, Cleton-Jansen, Nollet, de Leeuw, van de Vijver, Cornelisse, van Roy: "E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers." in: The EMBO journal, Vol. 14, Issue 24, pp. 6107-15, 1996

Overduin, Harvey, Bagby, Tong, Yau, Takeichi, Ikura: "Solution structure of the epithelial cadherin domain responsible for selective cell adhesion." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 386-9, 1995

Vestweber, Kemler: "Identification of a putative cell adhesion domain of uvomorulin." in: The EMBO journal, Vol. 4, Issue 13A, pp. 3393-8, 1986

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2657175) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (Alexa Fluor 647) (ABIN2657175) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (Alexa Fluor 647)
Immunofluorescence (IF) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (Alexa Fluor 647) (ABIN2657175) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (Alexa Fluor 647) (Image 2)