anti-Human E-cadherin Antikörper für Blocking Reagent

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • dZ71B9.1
  • si:dz180o5.1
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • CDH1
  • CDH16
  • HPT-1
  • HPT1
  • arc-1
  • cd324
  • cdhe
  • ecad
  • cad17
  • hpt1
  • cdh16
  • hpt-1
  • LI-cadherin
  • cadherin-17
  • b-cadherin
  • cdh1-a
  • cdhp
  • hjmd
  • pcad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • Arc1
  • cadherin 1, type 1, E-cadherin (epithelial)
  • si:busm1-180o5.2
  • cadherin 1, epithelial
  • cadherin 1
  • si:busm1-180o5.1
  • cadherin 17, LI cadherin (liver-intestine)
  • Cadherin-17
  • cadherin 3, type 1, P-cadherin (placental)
  • E-cadherin-like
  • Aerobic running capacity QTL 1
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • si:busm1-180o5.1
  • CDH17
  • cad17
  • cdh17
  • cdh3-a
  • LOC100356548
  • Arunc1
Reaktivität
Human
833
257
146
40
26
16
9
8
8
6
6
4
3
1
1
1
1
1
1
1
1
1
Wirt
Maus
566
274
51
25
2
Klonalität
Monoklonal
Konjugat
Dieser E-cadherin Antikörper ist konjugiert mit PE-Cy7
43
40
38
27
24
21
19
19
17
16
15
13
13
13
13
12
12
11
10
10
9
9
6
4
3
3
3
3
3
3
3
2
Applikation
Blocking Reagent (BR), Flow Cytometry (FACS)
651
398
285
215
194
174
164
90
88
38
23
14
13
12
10
7
6
6
4
4
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2659236
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2659237 BR FACS PE-Cy7 Mouse IgG1 kappa Anmelden zum Anzeigen 67A4 7

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Reaktivität Human
(833), (257), (146), (40), (26), (16), (9), (8), (8), (6), (6), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Maus
(566), (274), (51), (25), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser E-cadherin Antikörper ist konjugiert mit PE-Cy7
(43), (40), (38), (27), (24), (21), (19), (19), (17), (16), (15), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (6), (4), (3), (3), (3), (3), (3), (3), (3), (2)
Applikation Blocking Reagent (BR), Flow Cytometry (FACS)
(651), (398), (285), (215), (194), (174), (164), (90), (88), (38), (23), (14), (13), (12), (10), (7), (6), (6), (4), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2659236) Bilder
Produktmerkmale The 67A4 antibody recognizes human CD324 also known as E-cadherin, cadherin-1, and UVO. CD324, a member of the cadherin superfamily, is a calcium-dependent, transmembrane cell-cell adhesion glycoprotein composed of four extracellular cadherin repeats and a highly conserved cytoplasmic tail region with a predicted molecular weight of approximately 100 kD. CD324 is widely expressed in epithelial cells in the colon, uterus, liver, keratinocytes, brain, heart, muscle, kidney, and pancreas as well as erythroid cells. CD324 functions as a cell adhesion molecule involved in development, bacterial pathogenesis, and tumor invasion. In bacterial pathogenesis, the ectodomain of CD324 mediates bacterial adhesion to mammalian cells, while the cytoplasmic domain is required for internalization. CD324 binds to the αEβ7 integrin to mediate cell adhesion and also interacts with a number of intracellular proteins including including erbin, ezrin, caspase-3, caspase 8, β-catenin, presenilin 1, and casein kinase II as well as other extracellular proteins including the EGF receptor. CD324 is phosphorylated on multiple residues (S857, S866, S870, S872), and can be proteolytically cleaved at reside D769 by caspase-3.
Reinigung The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Klon 67A4
Isotyp IgG1 kappa

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2659236) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD324 (CDH1 Antibody Abstract)
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2659236) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN2659236) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-E-cadherin Antikörper (ABIN2659236)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Oeztuerk-Winder, Guinot, Ochalek, Ventura: "Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis." in: The EMBO journal, Vol. 31, Issue 16, pp. 3431-41, 2012

Yauch, Januario, Eberhard, Cavet, Zhu, Fu, Pham, Soriano, Stinson, Seshagiri, Modrusan, Lin, ONeill, Amler: "Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 24 Pt 1, pp. 8686-98, 2005

Perl, Wilgenbus, Dahl, Semb, Christofori: "A causal role for E-cadherin in the transition from adenoma to carcinoma." in: Nature, Vol. 392, Issue 6672, pp. 190-3, 1998

Berx, Cleton-Jansen, Nollet, de Leeuw, van de Vijver, Cornelisse, van Roy: "E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers." in: The EMBO journal, Vol. 14, Issue 24, pp. 6107-15, 1996

Bühring, Müller, Herbst, Cole, Rappold, Schuller, Zhu, Fritzsch, Faul, Armeanu, Ullrich, Klein, Schmidt: "The adhesion molecule E-cadherin and a surface antigen recognized by the antibody 9C4 are selectively expressed on erythroid cells of defined maturational stages." in: Leukemia, Vol. 10, Issue 1, pp. 106-16, 1996

Overduin, Harvey, Bagby, Tong, Yau, Takeichi, Ikura: "Solution structure of the epithelial cadherin domain responsible for selective cell adhesion." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 386-9, 1995

Armeanu, Bühring, Reuss-Borst, Müller, Klein: "E-cadherin is functionally involved in the maturation of the erythroid lineage." in: The Journal of cell biology, Vol. 131, Issue 1, pp. 243-9, 1995

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2659236) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (PE-Cy7) (ABIN2659236) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (PE-Cy7)