anti-DIAPH1 (DIAPH1) Antikörper

anti-Diaphanous Homolog 1 (Drosophila) Antikörper (DIAPH1)
Auf finden Sie aktuell 67 Diaphanous Homolog 1 (Drosophila) (DIAPH1) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DIAPH1 Proteine (6) und DIAPH1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 85 DIAPH1 Produkte verfügbar.
D18Wsu154e, DFNA1, DIA1, Diap1, Diaph1, DIAPH2, DRF1, hDIA1, LFHL1, mKIAA4062, p140mDia
Alle Antikörper anzeigen Gen GeneID UniProt
DIAPH1 307483  
DIAPH1 13367 O08808
DIAPH1 1729 O60610

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-DIAPH1 (DIAPH1) Antikörper

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anti-Rat (Rattus) DIAPH1 Antikörper:

anti-Mouse (Murine) DIAPH1 Antikörper:

anti-Human DIAPH1 Antikörper:

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Am meisten referenzierte anti-DIAPH1 Antikörper

  1. Human Polyclonal DIAPH1 Primary Antibody für WB - ABIN153169 : Minin, Kulik, Gyoeva, Li, Goshima, Gelfand: Regulation of mitochondria distribution by RhoA and formins. in Journal of cell science 2006 (PubMed)
    Zeige alle 4 Referenzen für 153169

  2. Dog (Canine) Monoclonal DIAPH1 Primary Antibody für IF, IP - ABIN968212 : Li, Higgs: The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. in Current biology : CB 2003 (PubMed)
    Zeige alle 3 Referenzen für 968212

  3. Human Polyclonal DIAPH1 Primary Antibody für ICC, IF - ABIN153170 : Jewett, Fischer, Mead, Hackstadt: Chlamydial TARP is a bacterial nucleator of actin. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Zeige alle 2 Referenzen für 153170

  4. Human Polyclonal DIAPH1 Primary Antibody für IHC, IHC (p) - ABIN4305203 : Goel, Sienkiewicz, Picciani, Lee, Bhattacharya: Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility. in PLoS ONE 2011 (PubMed)

Weitere Antikörper gegen DIAPH1 Interaktionspartner

Mouse (Murine) Diaphanous Homolog 1 (Drosophila) (DIAPH1) Interaktionspartner

  1. these results uncover a novel role for mDia1 in Abeta (zeige APP Antikörper)-mediated synaptotoxicity and demonstrate that inhibition of MT dynamics and accumulation of PTMs (zeige PTMS Antikörper) are driving factors for the induction of tau-mediated neuronal damage.

  2. Small Molecule Inhibition of Ligand-Stimulated RAGE (zeige AGER Antikörper)-DIAPH1 Signal Transduction.

  3. Diaphanous-related formin (zeige DIAPH3 Antikörper) signaling plays a role in heart and vascular development and the maintenance of SMC (zeige DYM Antikörper) phenotype.

  4. Liprin-alpha3 (zeige PPFIA3 Antikörper) uses an alpha-helical region to bind to mDia1, counteracting mouse Dia1 (zeige CYB5R3 Antikörper) activation by RhoA (zeige RHOA Antikörper).

  5. Depleting FMNL1 (zeige FMNL1 Antikörper), another Formin (zeige FMN1 Antikörper) family member, resulted in reduced mDia1 expression, while RhoA (zeige RHOA Antikörper) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1 (zeige FMNL1 Antikörper)-mDia1-Profilin1 (zeige PFN1 Antikörper) signaling pathway in mouse oocytes.

  6. Mechanistically, mDia1 deficiency led to a downregulation of membrane-associated genes and a specific upregulation of CD14 (zeige CD14 Antikörper) messenger RNA in granulocytes, but not in other lineages.

  7. Mammalian diaphanous-related formin 1 regulates GSK3beta (zeige GSK3b Antikörper)-dependent microtubule dynamics required for T cell migratory polarization.

  8. mDia1 can efficiently put actin filaments under mechanical tension.

  9. The active form of mDia1 localized to the apical membrane in exocrine pancreas cells; introduction of an active form of mDia1 leads to a marked increase in actin bundle density along the secretory vesicle lumen perimeter.

  10. Dia1 (zeige CYB5R3 Antikörper) and Dia2 (zeige DIAPH3 Antikörper) are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

Human Diaphanous Homolog 1 (Drosophila) (DIAPH1) Interaktionspartner

  1. Ligand-induced association of RAGE (zeige AGER Antikörper) homodimers on the cell surface increases the molecular dimension of the receptor, recruiting DIAPH1 and activating signaling pathways.

  2. The authors describe a novel patient-derived DIAPH1 mutation (c.3610C>T) in two unrelated families, which results in early termination prior to a basic amino acid motif (RRKR(1204-1207)) at the DAD C-terminus. The mutant DIA1 (zeige CYB5R3 Antikörper)(R1204X) disrupted the autoinhibitory DID-DAD interaction and was constitutively active.

  3. The description of a novel disorder of platelet formation and hearing loss extends the repertoire of DIAPH1-related disease, and provides new insight into the autoregulation of DIAPH1 activity.

  4. Studies indicate that diaphanous related formin 1 (DIAPH1) is essentially involved in microtubules (MTs (zeige TIMM8A Antikörper))-dependent early adhesion of colon cancer cells.

  5. A 51-year-old patient in a Korean family with ADNSHL was examined by pure-tone audiometry, and genetic analysis of DIAPH1 was performed. A novel variant, p.I530S (c.1589T > G), was identified in the DIAPH1 gene, and the mutation was located in the highly conserved coiled-coil domain of the DIA1 (zeige CYB5R3 Antikörper) protein.

  6. mDia1 is an important regulator of breast cancer cell invasion and that its effects may be mediated by MMP-2 (zeige MMP2 Antikörper) activity.

  7. Findings suggest that regulation of cellular trafficking and microtubule-mediated localization of MT1-MMP (zeige MMP14 Antikörper) by mDia1 is likely important in breast cancer invasion through the expression of cancer stem cell genes.

  8. Loss-of-function variants in DIAPH1 is associated with syndromic microcephaly, blindness, and early onset seizures.

  9. functional complementation experiments and optogenetics to show that mDia1 cooperates with the Arp2 (zeige ACTR2 Antikörper)/3 complex in initiating lamellipodia and ruffles.

  10. Capping protein and dia1 (zeige CYB5R3 Antikörper) functionally coregulate filament barbed-end assembly.

DIAPH1 Antigen-Profil

Beschreibung des Gens

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DIAPH1

  • diaphanous homolog 1 (Drosophila) (DIAPH1) Antikörper
  • diaphanous-related formin 1 (DIAPH1) Antikörper
  • diaphanous-related formin 1 (diaph1) Antikörper
  • diaphanous-related formin 1 (Diaph1) Antikörper
  • diaphanous homolog 1 (Drosophila) (diaph1) Antikörper
  • diaphanous homolog 1 (Drosophila) (Diap1) Antikörper
  • D18Wsu154e Antikörper
  • DFNA1 Antikörper
  • DIA1 Antikörper
  • Diap1 Antikörper
  • Diaph1 Antikörper
  • DIAPH2 Antikörper
  • DRF1 Antikörper
  • hDIA1 Antikörper
  • LFHL1 Antikörper
  • mKIAA4062 Antikörper
  • p140mDia Antikörper

Bezeichner auf Proteinebene für DIAPH1

diaphanous homolog 1 (Drosophila) , diaphanous homolog 1 , diaphanous homolog 2 , protein diaphanous homolog 1 , protein diaphanous homolog 1-like , diaphanous-related formin-1 , mDIA1

100684883 Canis lupus familiaris
700918 Macaca mulatta
786565 Bos taurus
733754 Xenopus (Silurana) tropicalis
100072186 Equus caballus
374040 Gallus gallus
307483 Rattus norvegicus
100457442 Pongo abelii
100478130 Ailuropoda melanoleuca
100562222 Anolis carolinensis
13367 Mus musculus
1729 Homo sapiens
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